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Invitrogen
Carbonic Anhydrase II Polyclonal Antibody
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FIGURE: 1 / 9
Carbonic Anhydrase II Antibody (PA5-78897) in IHC (P)
Immunohistochemistry analysis of Carbonic Anhydrase II on paraffin-embedded human gastric cancer tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with Carbonic Anhydrase II polyclonal antibody (Product# PA5-78897) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-... View More
Product Details
PA5-78897
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human CA2 recombinant protein (Position: S2-K260).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human 293T whole cell, human THP-1 whole cell, human HEL whole cell, rat kidney tissue, rat stomach tissue, mouse kidney tissue, mouse stomach tissue. IHC: human gastric cancer tissue, human liver cancer tissue. Flow: HT-29 cell, SW480 cell.
Target Information
CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CA II; CA-II; CA2; CAC; Carbonate dehydratase II; Carbonic anhydrase 2; carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; carbonic dehydratase; Cyanamide hydratase CA2; epididymis luminal protein 76; epididymis secretory protein Li 282; unnamed protein product
Gene Aliases: AI131712; CA-II; CA2; CAC; CAII; Car-2; Car2; HEL-76; HEL-S-282; Ltw-5; Lvtw-5
UniProt ID: (Human) P00918, (Mouse) P00920, (Rat) P27139
Entrez Gene ID: (Human) 760, (Mouse) 12349, (Rat) 54231
morphogenesis of an epithelium
one-carbon metabolic process
regulation of pH
carbon dioxide transport
positive regulation of synaptic transmission, GABAergic
positive regulation of cellular pH reduction
angiotensin-activated signaling pathway
regulation of anion transport
positive regulation of osteoclast differentiation
positive regulation of bone resorption
secretion
regulation of intracellular pH
positive regulation of dipeptide transmembrane transport
regulation of chloride transport
neuron cellular homeostasis
kidney development
response to pH
response to organic substance
response to zinc ion
osteoclast differentiation
regulation of cellular pH
odontogenesis of dentin-containing tooth
response to estrogen
regulation of bone resorption
response to steroid hormone
cellular response to fluid shear stress
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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