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Invitrogen
Calpain S1 Polyclonal Antibody
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Product Details
PA5-82266
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CAPNS1. Recombinant protein control fragment (Product #RP-89222).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: THYSNIEANE SEEVRQFRRL FAQLAGDDME VSATELMNIL NKVVTRHPDL KTDGFGIDTC RSMVAVMDSD TTGKLGFEEF KYLWNNIKRW QAIYKQFDTD RSGTICSSEL PG
Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 94%.
Target Information
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 30K; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4; calpain 4, small subunit (30K); Calpain regulatory subunit; Calpain small subunit 1; calpain, small polypeptide; CANP small subunit; CDPS; CSS1; epididymis secretory sperm binding protein; small pol; unnamed protein product
Gene Aliases: CALPAIN4; CANP; CANPS; Capa-4; Capa4; CAPN4; CAPNS; CAPNS1; CDPS; CSS1; D7Ertd146e; PPH6
UniProt ID: (Human) P04632, (Mouse) O88456, (Rat) Q64537
Entrez Gene ID: (Human) 826, (Mouse) 12336, (Rat) 29156
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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