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Invitrogen
hnRNP DL Polyclonal Antibody
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Product Details
PA5-88026
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 261-420 of human HNRNPDL (NP_1127401)
Conjugate
Form
Liquid
Concentration
1.38 mg/mL
Amount
138 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NIELPMDTKT NERRGFCFIT YTDEEPVKKL LESRYHQIGS GKCEIKVAQP KEVYRQQQQQ QKGGRGAAAG GRGGTRGRGR GQGQNWNQGF NNYYDQGYGN YNSAYGGDQN YSGYGGYDYT GYNYGNYGYG QGYADYSGQQ STYGKASRGG GNHQNNYQPY; Positive Samples: Jurkat, SW620, HepG2, Mouse brain, Mouse testis, Rat brain; Cellular Location: Cytoplasm, Nucleus
Target Information
hnRNP DL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A+U-rich element RNA binding factor; AU-rich element RNA-binding factor; Heterogeneous nuclear ribonucleoprotein D-like; hnRNP D-like; hnRNP DL; hnRNP JKTBP; hnRNP-DL; hnRPD-like protein; HNRPDL; JKT41-binding protein; limb girdle muscular dystrophy 1G (autosomal dominant); Protein laAUF1; transcription factor; unnamed protein product
Gene Aliases: AA407431; AA959857; D5Ertd650e; D5Wsu145e; HNRNP; hnRNP DL; hnRNP-DL; HNRNPDL; Hnrnpdl1; HNRPDL; JKTBP; JKTBP2; laAUF1; LGMD1G; LGMDD3
UniProt ID: (Human) O14979, (Rat) Q3SWU3
Entrez Gene ID: (Human) 9987, (Rat) 305178, (Mouse) 50926
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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