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Invitrogen
KCNK10 Polyclonal Antibody
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FIGURE: 1 / 1
KCNK10 Antibody (PA5-88217) in WB
Western blot analysis of KCNK10 in extracts of various cell lines. Samples were incubated with KCNK10 Polyclonal antibody (Product # PA5-88217) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-88217
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 384-543 of human KCNK10 (NP_6121911)
Conjugate
Form
Liquid
Concentration
1.37 mg/mL
Amount
137 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: RLGLDQRAHS LDMLSPEKRS VFAALDTGRF KASSQESINN RPNNLRLKGP EQLNKHGQGA SEDNIINKFG STSRLTKRKN KDLKKTLPED VQKIYKTFRN YSLDEEKKEE ETEKMCNSDN SSTAMLTDCI QQHAELENGM IPTDTKDREP ENNSLLEDRN; Positive Samples: U-87MG, HT-29; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
KCNK10 is one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is highly expressed in the kidney and pancreas. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. The protein is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Three transcript variants have been identified for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2P domain potassium channel TREK2; KCNK10; Outward rectifying potassium channel protein TREK-2; Potassium channel subfamily K member 10; potassium channel TREK-2; potassium channel, subfamily K, member 10; potassium channel, two pore domain subfamily K, member 10; protein phosphatase 1, regulatory subunit 97; TREK-2 K(+) channel subunit; TWIK-related K+ channel 2; two-pore-domain potassium channel subunit; unnamed protein product
Gene Aliases: K2p10.1; KCNK10; PPP1R97; TREK-2; TREK2
UniProt ID: (Human) P57789
Entrez Gene ID: (Human) 54207
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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