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Invitrogen
KCNE4 Polyclonal Antibody
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FIGURE: 1 / 1
KCNE4 Antibody (PA5-88404) in WB
Western blot analysis of KCNE4 in extracts of various cell lines. Samples were incubated with KCNE4 Polyclonal antibody (Product # PA5-88404) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-88404
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 108-221 of human KCNE4 (NP_5424023)
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Amount
150 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: YMKSKRREKK SSLLLLYKDE ERLWGEAMKP LPVVSGLRSV QVPLMLNMLQ ESVAPALSCT LCSMEGDSVS SESSSPDVHL TIQEEGADDE LEETSETPLN ESSEGSSENI HQNS; Positive Samples: 293T, LO2; Cellular Location: Membrane, Single-pass membrane protein
Target Information
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. May associate with KCNQ1/KVLTQ1 and inhibit potassium current.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac voltage-gated potassium channel accessory subunit 4; Minimum potassium ion channel-related peptide 3; MINK-related peptide 3; MIRP3; MiRP3; Isk-related subfamily; Potassium channel subunit beta MiRP3; potassium channel, voltage gated subfamily E regulatory beta subunit 4; Potassium voltage-gated channel subfamily E member 4; potassium voltage-gated channel, Isk-related family, member 4; unnamed protein product
Gene Aliases: KCNE4; MIRP3
UniProt ID: (Human) Q8WWG9
Entrez Gene ID: (Human) 23704
voltage-gated potassium channel activity
delayed rectifier potassium channel activity
potassium channel activity
protein binding
potassium channel regulator activity
potassium channel inhibitor activity
ion channel binding
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
ion transport
potassium ion transport
ion transmembrane transport
regulation of ventricular cardiac muscle cell membrane repolarization
potassium ion transmembrane transport
ventricular cardiac muscle cell action potential
membrane repolarization during action potential
regulation of heart rate by cardiac conduction
potassium ion export across plasma membrane
membrane repolarization during ventricular cardiac muscle cell action potential
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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