Search
Abnova
COL3A1 Recombinant Rabbit Monoclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 2
COL3A1 Antibody (RAB02484) in ICC/IF
Immunofluorescent analysis of HeLa cells with Collagen 3 alpha 1 recombinant monoclonal antibody (Product # RAB02484). Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humified chamber. Cells were washed with PBST and incubated with a AF488-conjugated secondary antibody (green) in PBS at room temperature in the dark.
Product Details
RAB02484
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
50mM tris glycine, pH 7.4, with 0.05% BSA, 150mM NaCl, 50% glycerol
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in th gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: alpha-1 type III collagen; alpha-1(III) procollagen; alpha1 (III) collagen; COL 3; COL3; COL3 alpha 1; Collagen 3; Collagen alpha-1(III) chain; collagen, fetal; collagen, type III, alpha 1; Collagen3; Ehlers-Danlos syndrome type IV, autosomal dominant; FLJ34534; MGC93704; minisatellite 10w detected by probe MMS10; procollagen, type III, alpha 1; unnamed protein product
Gene Aliases: AW550625; Col3a-1; COL3A1; EDS4A; EDSVASC; mKIAA4231; MMS10-W; Ms10w; PMGEDSV
UniProt ID: (Human) P02461, (Mouse) P08121, (Rat) P13941
Entrez Gene ID: (Human) 1281, (Mouse) 12825, (Rat) 84032
blood vessel development
in utero embryonic development
neuron migration
tissue homeostasis
chondrocyte differentiation
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
heart development
response to radiation
gene expression
peptide cross-linking
layer formation in cerebral cortex
cerebral cortex development
platelet activation
extracellular matrix organization
collagen fibril organization
lung development
transforming growth factor beta1 production
response to cytokine
positive regulation of Rho protein signal transduction
multicellular organism growth
aorta development
limb joint morphogenesis
wound healing
skin development
fibroblast proliferation
elastic fiber assembly
animal organ development
digestive tract development
system development
negative regulation of immune response
cartilage development
endochondral bone morphogenesis
aorta smooth muscle tissue morphogenesis
cellular response to amino acid stimulus
basement membrane organization
fibril organization
response to angiotensin
negative regulation of neuron migration
extracellular fibril organization
skeletal system development
aging
response to mechanical stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support