Search
OriGene
TRDMT1 Monoclonal Antibody (OTI8H10), TrueMAB™
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 2
TRDMT1 Antibody (TA811494) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRDMT1 (RC208363, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-TRDMT. Positive lysates LY401401 (100 µg) and LC401401 (20 µg) can be purchased separately from OriGene.
Product Details
TA811494
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI8H10
Immunogen
Human recombinant protein fragment corresponding to amino acids 84-293 of human TRDMT1 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DNA (cytosine-5)-methyltransferase-like protein 2; DNA cytosine-5 methyltransferase 2; DNA methyltransferase 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase homolog MmuIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNA MTase homolog MmuIIP; DNMT2; DNMT2b; DNMT2c; DNMT2d; DNMT2e; DNMT2f; homolog to yeast pmt1; M.HsaIIP; m.MmuIIP; Met-2; PuMet; RP11-406H21.1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase; unnamed protein product
Gene Aliases: DMNT2; DNMT2; Met2; MHSAIIP; PUMET; RNMT1; Rnmt2; TRDMT1
UniProt ID: (Human) O14717, (Mouse) O55055
Entrez Gene ID: (Human) 1787, (Mouse) 13434
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support