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          • Home
          • › Search Tool
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          • › Hs00169258_m1
          See other F2R GE Assays ›
          Gene Symbol:
          F2R
          Gene Name:
          coagulation factor II thrombin receptor
          Gene Aliases:
          CF2R, HTR, PAR-1, PAR1, TR
          Chromosome Location:
          Chr.5: 76716043 - 76735780 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs00169258_m1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price 284.00
          Your Price
          Online offer: 266.65
          266.65
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (1)

          Genomic Map

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          Assay Details

          Gene Symbol: F2R
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_001992.4 NP_001983.2 1 - 2 355 74
          GenBank mRNA AK308169.1 - 1 - 2 355 74
          AK314202.1 - 1 - 2 278 74
          BC002464.2 - 1 - 2 270 3343051 74
          BC051909.1 - 1 - 2 276 6172703 74
          BT007279.1 - 1 - 2 90 74
          M62424.1 - 1 - 2 314 74

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          More Information


          Updated Mapping Information

          This assay targets the same location as Clariom D transcript cluster(s) TC0500007831.hg.1
          This assay targets the same location as HTA transcript cluster(s) TC05000370.hg.1

          Set Membership:

          Ambion siRNA available Amplicon length between 71 and 85 G-protein coupled receptor Immune Tolerance Network Mammalian Gene Collection Homo sapiens HUMAN THROMBIN SIGNALING 1700 Inventoried Human_Thrombin_Signaling Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene F2R

          Panther Classification:

          Molecular Function -

          G-protein coupled receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPKK activity
          connective tissue replacement involved in inflammatory response wound healing
          negative regulation of glomerular filtration
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          inflammatory response
          G-protein coupled receptor signaling pathway
          phospholipase C-activating G-protein coupled receptor signaling pathway
          positive regulation of cytosolic calcium ion concentration
          protein kinase C-activating G-protein coupled receptor signaling pathway
          tyrosine phosphorylation of STAT protein
          STAT protein import into nucleus
          establishment of synaptic specificity at neuromuscular junction
          blood coagulation
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          response to wounding
          anatomical structure morphogenesis
          positive regulation of phosphatidylinositol 3-kinase signaling
          platelet activation
          regulation of blood coagulation
          positive regulation of blood coagulation
          positive regulation of cell migration
          response to lipopolysaccharide
          regulation of interleukin-1 beta production
          positive regulation of collagen biosynthetic process
          positive regulation of Rho protein signal transduction
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
          positive regulation of MAPK cascade
          negative regulation of neuron apoptotic process
          positive regulation of transcription, DNA-templated
          positive regulation of vasoconstriction
          positive regulation of smooth muscle contraction
          positive regulation of JAK-STAT cascade
          homeostasis of number of cells within a tissue
          release of sequestered calcium ion into cytosol
          positive regulation of release of sequestered calcium ion into cytosol
          positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
          positive regulation of calcium ion transport
          regulation of sensory perception of pain
          platelet dense granule organization
          positive regulation of ERK1 and ERK2 cascade
          thrombin receptor signaling pathway
          negative regulation of renin secretion into blood stream
          positive regulation of interleukin-8 secretion
          positive regulation of interleukin-6 secretion
          G-protein alpha-subunit binding
          G-protein coupled receptor activity
          receptor binding
          protein binding
          thrombin receptor activity
          G-protein beta-subunit binding

          MicroArray Probes:

          Affymetrix ABI

          Array Name Probe IDs Targets Target Type
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000319211.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000319211.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000319211.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000319211.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000319211.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000319211.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000319211.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000319211.4 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000505600.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000505600.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 ENST00000505600.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001311313.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001311313.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001311313.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001311313.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001311313.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001311313.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001311313.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001311313.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001311313.1 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001992.4 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001992.4 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001992.4 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001992.4 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001992.4 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001992.4 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001992.4 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500007831.hg.1 NM_001992.4 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC0500011195.hg.1 ENST00000507514.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500011195.hg.1 ENST00000507514.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500011195.hg.1 ENST00000507514.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC0500011195.hg.1 ENST00000507514.1 Ensembl
          Affymetrix Human Clariom D Assay TC0500011195.hg.1 ENST00000507514.1 Ensembl
          Affymetrix Human Clariom D Assay TC0500011195.hg.1 ENST00000507514.1 Ensembl
          Affymetrix Human Clariom D Assay TC0500011195.hg.1 ENST00000507514.1 Ensembl
          Affymetrix Human Clariom D Assay TC0500011195.hg.1 ENST00000507514.1 Ensembl
          Array Name Probe IDs Targets Target Type
          ABI Human Genome Survey Microarray Version 2.0 158262 - -

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          Citations (1)

          Coagulation factor Xa stimulates interleukin-8 release in endothelial cells and mononuclear leukocytes: implications in acute myocardial infarction.
          Authors
          Busch G, Seitz I, Steppich B, Hess S, Eckl R, Schomig A, Ott I
          Journal
          Arterioscler Thromb Vasc Biol - Page No 461 (Tue Feb 01 00:00:00 EST 2005)
          Volume (Year)
          25 (2005)
          Product Usage
          -

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