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          • Home
          • › Search Tool
          • › Search Results
          • › Hs00174143_m1
          See other IFNG GE Assays ›
          Gene Symbol:
          IFNG
          Gene Name:
          interferon gamma
          Gene Aliases:
          IFG, IFI, IMD69
          Chromosome Location:
          Chr.12: 68154768 - 68159740 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs00174143_m1
          Size
          Availability Inventoried
          Catalog # 4331182
          Price 284.00
          Your Price
          Online offer: 266.65
          266.65
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (31)

          Genomic Map

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          Assay Details

          Gene Symbol: IFNG
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_000619.3 NP_000610.2 1 - 2 245 79
          GenBank mRNA AB451324.1 - 1 - 2 120 79
          AB451453.1 - 1 - 2 120 79
          AF506749.1 - 1 - 2 54 79
          AM903379.1 - 1 - 2 133 79
          AY044154.1 - 1 - 2 51 79
          AY255837.1 - 1 - 2 120 79
          AY255839.1 - 1 - 2 54 79
          BC070256.1 - 1 - 2 248 79
          V00543.1 - 1 - 2 211 79
          X13274.1 - 1 - 2 228 79
          X87308.1 - 1 - 2 60 79

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          More Information


          Updated Mapping Information

          This assay targets the same location as Clariom D transcript cluster(s) TC1200011177.hg.1
          This assay targets the same location as HTA transcript cluster(s) TC12001696.hg.1

          Set Membership:

          Ambion siRNA available Amplicon length between 71 and 85 Immune Tolerance Network Mammalian Gene Collection Homo sapiens Human Androgen Panel Human Chemokine Panel Human TGFB Panel Human Immune Response Human Alzheimer's Disease Human Diabetes Human Angiogenesis Inventoried Human_Immune Human_Angiogenesis Human_Androgen Human_Diabetes Human_Chemokine Human_TGFB Human_Alzheimer Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene IFNG

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          microglial cell activation
          positive regulation of cytokine production
          adaptive immune response
          macrophage activation involved in immune response
          positive regulation of T cell cytokine production
          apoptotic process
          immune response
          humoral immune response
          cell surface receptor signaling pathway
          JAK-STAT cascade
          positive regulation of cell proliferation
          response to virus
          positive regulation of autophagy
          positive regulation of gene expression
          negative regulation of gene expression
          positive regulation of epithelial cell migration
          macrophage differentiation
          negative regulation of epithelial cell differentiation
          positive regulation of protein complex assembly
          negative regulation of interleukin-17 production
          positive regulation of chemokine production
          positive regulation of interleukin-1 beta production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-23 production
          positive regulation of interleukin-6 production
          positive regulation of tumor necrosis factor production
          positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
          positive regulation of peptidyl-serine phosphorylation of STAT protein
          positive regulation of smooth muscle cell apoptotic process
          Fc-gamma receptor signaling pathway involved in phagocytosis
          interleukin-2-mediated signaling pathway
          type III interferon-mediated signaling pathway
          positive regulation of protein import into nucleus
          positive regulation of tyrosine phosphorylation of STAT protein
          positive regulation of MHC class II biosynthetic process
          positive regulation of nitric oxide biosynthetic process
          positive regulation of osteoclast differentiation
          positive regulation of cell adhesion
          positive regulation of glycolytic process
          negative regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          astrocyte activation
          negative regulation of smooth muscle cell proliferation
          positive regulation of inflammatory response
          positive regulation of phagocytosis
          positive regulation of neurogenesis
          regulation of insulin secretion
          positive regulation of membrane protein ectodomain proteolysis
          positive regulation of transport
          defense response to virus
          interferon-gamma-mediated signaling pathway
          positive regulation of fructose 1,6-bisphosphate metabolic process
          positive regulation of vitamin D biosynthetic process
          positive regulation of protein serine/threonine kinase activity
          positive regulation of protein deacetylation
          extrinsic apoptotic signaling pathway
          receptor signaling pathway via STAT
          cellular response to virus
          neuroinflammatory response
          negative regulation of beta-amyloid clearance
          positive regulation of glutamate receptor signaling pathway
          positive regulation of cellular respiration
          positive regulation of beta-amyloid formation
          positive regulation of protein localization to plasma membrane
          positive regulation of exosomal secretion
          positive regulation of iron ion import across plasma membrane
          positive regulation of core promoter binding
          positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
          cytokine activity
          interferon-gamma receptor binding
          protein binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Human Transcriptome Array 2.0 PSR12022636.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR12022636.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR12022636.hg.1 TC12001696.hg.1 HTA TC
          Affymetrix Human Transcriptome Array 2.0 PSR12022635.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR12022635.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR12022635.hg.1 TC12001696.hg.1 HTA TC
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay TC1200011177.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186694.hg.1 TC1200011177.hg.1 Clariom D TC
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186693.hg.1 TC1200011177.hg.1 Clariom D TC
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186690.hg.1 TC1200011177.hg.1 Clariom D TC
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 ENST00000229135.3 Ensembl
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 NM_000619.2 Refseq
          Affymetrix Human Clariom D Assay PSR1200186692.hg.1 TC1200011177.hg.1 Clariom D TC

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          Citations (31)

          The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro.
          Authors
          Scholz H, Lund T, Dahle MK, Collins JL, Korsgren O, Wang JE, Foss A
          Journal
          Diabetologia - Page No 1352 (Wed Jul 01 00:00:00 UTC 2009)
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          52 (2009)
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          Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin.
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          Johansen C, Usher PA, Kjellerup RB, Lundsgaard D, Iversen L, Kragballe K
          Journal
          Br J Dermatol - Page No 319 (Sun Feb 01 00:00:00 UTC 2009)
          Volume (Year)
          160 (2009)
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          Effects of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on cytokine production by human decidual cells.
          Authors
          Evans KN, Nguyen L, Chan J, Innes BA, Bulmer JN, Kilby MD, Hewison M
          Journal
          Biol Reprod - Page No 816 (Fri Dec 01 00:00:00 UTC 2006)
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          75 (2006)
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          Intragraft expression of the IL-10 gene is up-regulated in renal protocol biopsies with early interstitial fibrosis, tubular atrophy, and subclinical rejection.
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          Hueso M, Navarro E, Moreso F, O'Valle F, Perez-Riba M, Del Moral RG, Grinyo JM, Seron D
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          Am J Pathol - Page No 1696 (Thu Apr 01 00:00:00 UTC 2010)
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          Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome.
          Authors
          Chetaille B, Bertucci F, Finetti P, Esterni B, Stamatoullas A, Picquenot JM, Copin MC, Morschhauser F, Casasnovas O, Petrella T, Molina T, Vekhoff A, Feugier P, Bouabdallah R, Birnbaum D, Olive D, Xerri L
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          Blood - Page No 2765 (Thu Mar 19 00:00:00 UTC 2009)
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          113 (2009)
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          Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells.
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          Ito T, Kanzler H, Duramad O, Cao W, Liu YJ
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          Blood - Page No 2423 (Wed Mar 15 00:00:00 UTC 2006)
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          Hypercytokinaemia accompanies HIV-tuberculosis immune reconstitution inflammatory syndrome.
          Authors
          Tadokera R, Meintjes G, Skolimowska KH, Wilkinson KA, Matthews K, Seldon R, Chegou NN, Maartens G, Rangaka MX, Rebe K, Walzl G, Wilkinson RJ
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          Gene expression profiles in psoriasis: analysis of impact of body site location and clinical severity.
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          Quekenborn-Trinquet V, Fogel P, Aldana-Jammayrac O, Ancian P, Demarchez M, Rossio P, Richards HL, Kirby B, Nguyen C, Voegel JJ, Griffiths CE
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          Br J Dermatol - Page No 489 (Tue Mar 01 00:00:00 UTC 2005)
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          152 (2005)
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          IL-21 induces in vivo immune activation of NK cells and CD8(+) T cells in patients with metastatic melanoma and renal cell carcinoma.
          Authors
          Frederiksen KS, Lundsgaard D, Freeman JA, Hughes SD, Holm TL, Skrumsager BK, Petri A, Hansen LT, McArthur GA, Davis ID, Skak K
          Journal
          Cancer Immunol Immunother - Page No 1439 (Wed Oct 01 00:00:00 UTC 2008)
          Volume (Year)
          57 (2008)
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          Altered expression of T cell immunoglobulin-mucin (TIM) molecules in bronchoalveolar lavage CD4+ T cells in sarcoidosis.
          Authors
          Idali F, Wahlstrom J, Dahlberg B, Khademi M, Olsson T, Eklund A, Grunewald J
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          Respir Res - Page No 42 (Thu Jan 01 00:00:00 UTC 2009)
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          10 (2009)
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          Evasion of the mucosal innate immune system by herpes simplex virus type 2.
          Authors
          Peng T, Zhu J, Klock A, Phasouk K, Huang ML, Koelle DM, Wald A, Corey L
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          J Virol - Page No 12559 (Tue Dec 01 00:00:00 UTC 2009)
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          Inflammatory and microRNA Gene Expression as Prognostic Classifiers of Barrett's Associated Esophageal Adenocarcinoma.
          Authors
          Nguyen GH, Schetter AJ, Chou DB, Bowman ED, Zhao R, Hawkes JE, Mathe E, Kumamoto K, Zhao Y, Budhu A, Hagiwara N, Wang XW, Miyashita M, Casson AG, Harris CC
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          Clin Cancer Res - Page No (Mon Oct 25 00:00:00 UTC 2010)
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          Comparing microarray versus RT-PCR assessment of renal allograft biopsies: similar performance despite different dynamic ranges.
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          Allanach K, Mengel M, Einecke G, Sis B, Hidalgo LG, Mueller T, Halloran PF
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          Am J Transplant - Page No 1006 (Thu May 01 00:00:00 UTC 2008)
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          8 (2008)
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          New means to monitor the effect of glucocorticoid therapy in children.
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          Rintamaki H, Salo HM, Vaarala O, Kolho KL
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          World J Gastroenterol - Page No 1104 (Sun Mar 07 00:00:00 UTC 2010)
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          T helper 2 biased de novo immune response to Keyhole Limpet Hemocyanin in humans.
          Authors
          Spazierer D, Skvara H, Dawid M, Fallahi N, Gruber K, Rose K, Lloyd P, Heuerding S, Stingl G, Jung T
          Journal
          Clin Exp Allergy - Page No 999 (Wed Jul 01 00:00:00 UTC 2009)
          Volume (Year)
          39 (2009)
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          Prospective monitoring of tumor necrosis factor alpha and interferon gamma to predict the onset of acute and chronic graft-versus-host disease after allogeneic stem cell transplantation.
          Authors
          Ritchie D, Seconi J, Wood C, Walton J, Watt V
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          Biol Blood Marrow Transplant - Page No 706 (Thu Sep 01 00:00:00 UTC 2005)
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          11 (2005)
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          Regulation of the tonsil cytokine milieu favors HIV susceptibility.
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          Moutsopoulos NM, Vazquez N, Greenwell-Wild T, Ecevit I, Horn J, Orenstein J, Wahl SM
          Journal
          J Leukoc Biol - Page No 1145 (Wed Nov 01 00:00:00 UTC 2006)
          Volume (Year)
          80 (2006)
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          Anti-CD25 treatment and FOXP3-positive regulatory T cells in heart transplantation.
          Authors
          Vlad G, Ho EK, Vasilescu ER, Fan J, Liu Z, Cai JW, Jin Z, Burke E, Deng M, Cadeiras M, Cortesini R, Itescu S, Marboe C, Mancini D, Suciu-Foca N
          Journal
          Transpl Immunol - Page No 13 (Sun Jul 01 00:00:00 UTC 2007)
          Volume (Year)
          18 (2007)
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          Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone.
          Authors
          Sandig H, McDonald J, Gilmour J, Arno M, Lee TH, Cousins DJ
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          Proc Natl Acad Sci U S A - Page No 12440 (Tue Jul 24 00:00:00 UTC 2007)
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          104 (2007)
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          Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions.
          Authors
          Simon D, Lindberg RL, Kozlowski E, Braathen LR, Simon HU
          Journal
          Exp Dermatol - Page No 441 (Thu Jun 01 00:00:00 UTC 2006)
          Volume (Year)
          15 (2006)
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          Soluble Ig-like transcript 3 inhibits tumor allograft rejection in humanized SCID mice and T cell responses in cancer patients.
          Authors
          Suciu-Foca N, Feirt N, Zhang QY, Vlad G, Liu Z, Lin H, Chang CC, Ho EK, Colovai AI, Kaufman H, D'Agati VD, Thaker HM, Remotti H, Galluzzo S, Cinti P, Rabitti C, Allendorf J, Chabot J, Caricato M, Coppola R, Berloco P, Cortesini R
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          J Immunol - Page No 7432 (Fri Jun 01 00:00:00 UTC 2007)
          Volume (Year)
          178 (2007)
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          Postmenopausal expression changes of immune system-related genes in human bone tissue.
          Authors
          Kosa JP, Balla B, Kiss J, Podani J, Takacs I, Lazary A, Nagy Z, Bacsi K, Karsai A, Speer G, Lakatos P
          Journal
          J Clin Immunol - Page No 761 (Sun Nov 01 00:00:00 UTC 2009)
          Volume (Year)
          29 (2009)
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          Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability.
          Authors
          Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Kitazume MT, Takayama T, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T
          Journal
          J Immunol - Page No 1724 (Sat Aug 01 00:00:00 UTC 2009)
          Volume (Year)
          183 (2009)
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          Characterization of the innate immune signalling pathways in hepatocyte cell lines.
          Authors
          Preiss S, Thompson A, Chen X, Rodgers S, Markovska V, Desmond P, Visvanathan K, Li K, Locarnini S, Revill P
          Journal
          J Viral Hepat - Page No 888 (Mon Dec 01 00:00:00 UTC 2008)
          Volume (Year)
          15 (2008)
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          Interferon-gamma expression is an independent prognostic factor in ovarian cancer.
          Authors
          Marth C, Fiegl H, Zeimet AG, Muller-Holzner E, Deibl M, Doppler W, Daxenbichler G
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          Am J Obstet Gynecol - Page No 1598 (Mon Nov 01 00:00:00 UTC 2004)
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          191 (2004)
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          Using distinct molecular signatures of human monocytes and dendritic cells to predict adjuvant activity and pyrogenicity of TLR agonists.
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          Kamgang RK, Ramos I, Rodrigues Duarte L, Ghielmetti M, Freudenberg M, Dahinden C, Padovan E
          Journal
          Med Microbiol Immunol - Page No 369 (Mon Dec 01 00:00:00 UTC 2008)
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          197 (2008)
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          Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators.
          Authors
          Duffaut C, Zakaroff-Girard A, Bourlier V, Decaunes P, Maumus M, Chiotasso P, Sengenes C, Lafontan M, Galitzky J, Bouloumie A
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          Arterioscler Thromb Vasc Biol - Page No 1608 (Thu Oct 01 00:00:00 UTC 2009)
          Volume (Year)
          29 (2009)
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          The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.
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          Wolf D, Wolf AM, Rumpold H, Fiegl H, Zeimet AG, Muller-Holzner E, Deibl M, Gastl G, Gunsilius E, Marth C
          Journal
          Clin Cancer Res - Page No 8326 (Thu Dec 01 00:00:00 UTC 2005)
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          11 (2005)
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          Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide.
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          Barksby HE, Nile CJ, Jaedicke KM, Taylor JJ, Preshaw PM
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          Clin Exp Immunol - Page No 479 (Mon Jun 01 00:00:00 UTC 2009)
          Volume (Year)
          156 (2009)
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          Local and systemic cytokine and chemokine responses after parenteral influenza vaccination.
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          Eriksson JC, Cox RJ, Szyszko E, Davidsson A, Brokstad KA
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          Influenza Other Respi Viruses - Page No 139 (Sun Jul 01 00:00:00 UTC 2007)
          Volume (Year)
          1 (2007)
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          Phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, potentiates innate immune activation and induces apoptosis in human monocytes.
          Authors
          Cruz AR, Moore MW, La Vake CJ, Eggers CH, Salazar JC, Radolf JD
          Journal
          Infect Immun - Page No 56 (Tue Jan 01 00:00:00 UTC 2008)
          Volume (Year)
          76 (2008)
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          Host server : magellan-search-green-7b6576f7bc-knt4q:80/100.66.75.14:80.
          git-commit: 6d309ebe7a31b2ceadeb87f43b473eebab110cf3
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.46.0-2026.03.11-1.0