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          • Home
          • › Search Tool
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          • › Mm00477784_m1
          See other NFE2L2 GE Assays ›
          Gene Symbol:
          Nfe2l2
          Gene Name:
          nuclear factor, erythroid derived 2, like 2
          Gene Aliases:
          AI194320, Nrf2
          Chromosome Location:
          Chr.2: 75675519 - 75704641 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00477784_m1
          Best Coverage
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
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          Online offer:
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (1)

          Genomic Map

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          Assay Details

          Gene Symbol: Nfe2l2
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_010902.3 NP_035032.1 1 - 2 279 61
          GenBank mRNA AK142347.1 - 1 - 2 181 61
          AK144247.1 - 1 - 2 153 61
          BC003340.1 - 1 - 2 135 61
          BC026943.1 - 1 - 2 220 3663276 61
          BY792550.1 - 1 - 2 279 61

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC0200003791.mm.1

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Mammalian Gene Collection Recommended Assay Mus musculus Inventoried Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Nfe2l2

          Panther Classification:

          Molecular Function -

          basic leucine zipper transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          transcription, DNA-templated
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          inflammatory response
          proteasomal ubiquitin-independent protein catabolic process
          positive regulation of gene expression
          protein ubiquitination
          positive regulation of blood coagulation
          endoplasmic reticulum unfolded protein response
          cellular response to oxidative stress
          response to endoplasmic reticulum stress
          cellular response to drug
          positive regulation of transcription from RNA polymerase II promoter in response to stress
          positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
          PERK-mediated unfolded protein response
          cellular response to glucose starvation
          proteasome-mediated ubiquitin-dependent protein catabolic process
          cell redox homeostasis
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          regulation of embryonic development
          negative regulation of cell death
          cellular response to hydrogen peroxide
          cellular response to tumor necrosis factor
          cellular response to fluid shear stress
          cellular response to laminar fluid shear stress
          negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
          negative regulation of hydrogen peroxide-induced cell death
          positive regulation of glutathione biosynthetic process
          regulation of removal of superoxide radicals
          negative regulation of endothelial cell apoptotic process
          positive regulation of reactive oxygen species metabolic process
          transcription regulatory region sequence-specific DNA binding
          RNA polymerase II distal enhancer sequence-specific DNA binding
          RNA polymerase II activating transcription factor binding
          transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
          transcription cofactor binding
          DNA binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          protein domain specific binding
          sequence-specific DNA binding
          protein heterodimerization activity

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Mouse Clariom S Array PSR0200032405.mm.1 NM_010902.4 Refseq
          Affymetrix Mouse Clariom S Array PSR0200032405.mm.1 TC0200003791.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0200032407.mm.1 NM_010902.4 Refseq
          Affymetrix Mouse Clariom S Array PSR0200032407.mm.1 TC0200003791.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0200032409.mm.1 NM_010902.4 Refseq
          Affymetrix Mouse Clariom S Array PSR0200032409.mm.1 TC0200003791.mm.1 MTA TC
          Affymetrix Mouse Clariom S Array PSR0200032408.mm.1 NM_010902.4 Refseq
          Affymetrix Mouse Clariom S Array PSR0200032408.mm.1 TC0200003791.mm.1 MTA TC

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          Citations (1)

          An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance.
          Authors
          Kaspar JW, Jaiswal AK
          Journal
          J Biol Chem - Page No 21349 (Fri Jul 09 00:00:00 EDT 2010)
          Volume (Year)
          285 (2010)
          Product Usage
          -

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