Assay Details

Gene Symbol: Ifng
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_008337.3	NP_032363.1	1 - 2	222		101
GenBank mRNA	AK089574.1	-	1 - 2	223		101
	AY423847.1	-	1 - 2	71		101
	BC119063.1	-	1 - 2	151	8733812	101
	BC119065.1	-	1 - 2	151	8733814	101
	EF423643.1	-	1 - 2	114		101
	FJ617514.1	-	1 - 2	180		101
	FJ617515.1	-	1 - 2	180		101
	FJ617516.1	-	1 - 2	180		101
	K00083.1	-	1 - 2	183		101
	M28621.1	-	1 - 2	224		101

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC1000001452.mm.1

Set Membership:

Ambion siRNA available

Amplicon length greater than or equal to 101

Apoptosis

Mammalian Gene Collection

Mus musculus

Mouse Androgen Panel

Mouse Chemokine Panel

Mouse Tumor Metastasis Panel

Mouse Immune Response

Mouse Alzheimer's Disease

Inventoried

Mouse_Immune_Response

Mouse_Alzheimer

Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Ifng

Panther Classification:

Molecular Function -

cytokine

interferon superfamily

intercellular signal molecule

Gene Ontology Categories:

Function(s) Process(es)

MicroArray Probes:

Affymetrix

Citations (50)

TLR9 signaling is essential for the innate NK cell response in murine cutaneous leishmaniasis.

Authors: Liese J, Schleicher U, Bogdan C
Journal: Eur J Immunol - Page No 3424 (Sat Dec 01 00:00:00 EST 2007)
Volume (Year): 37 (2007)
Product Usage: -

Combined stimulation with interleukin-18 and CpG induces murine natural killer dendritic cells to produce IFN-gamma and inhibit tumor growth.

Authors: Chaudhry UI, Kingham TP, Plitas G, Katz SC, Raab JR, DeMatteo RP
Journal: Cancer Res - Page No 10497 (Wed Nov 01 00:00:00 EST 2006)
Volume (Year): 66 (2006)
Product Usage: -

Critical role for the chemokine receptor CXCR6 in homeostasis and activation of CD1d-restricted NKT cells.

Authors: Germanov E, Veinotte L, Cullen R, Chamberlain E, Butcher EC, Johnston B
Journal: J Immunol - Page No 81 (Tue Jul 01 00:00:00 EDT 2008)
Volume (Year): 181 (2008)
Product Usage: -

Systemic PPARgamma ligation inhibits allergic immune response in the skin.

Authors: Dahten A, Koch C, Ernst D, Schnoller C, Hartmann S, Worm M
Journal: J Invest Dermatol - Page No 2211 (Mon Sep 01 00:00:00 EDT 2008)
Volume (Year): 128 (2008)
Product Usage: -

Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease.

Authors: Johswich K, Martin M, Bleich A, Kracht M, Dittrich-Breiholz O, Gessner JE, Suerbaum S, Wende E, Rheinheimer C, Klos A
Journal: Inflamm Bowel Dis - Page No 1812 (Thu Aug 27 00:00:00 EDT 2009)
Volume (Year): 15 (2009)
Product Usage: -

IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons.

Authors: Curtis MM, Way SS, Wilson CB
Journal: J Immunol - Page No 381 (Wed Jul 01 00:00:00 EDT 2009)
Volume (Year): 183 (2009)
Product Usage: -

Cytokines, signaling pathways, and effector molecules required for the control of Leishmania (Viannia) braziliensis in mice.

Authors: Rocha FJ, Schleicher U, Mattner J, Alber G, Bogdan C
Journal: Infect Immun - Page No 3823 (Wed Aug 01 00:00:00 EDT 2007)
Volume (Year): 75 (2007)
Product Usage: -

Foxa2 programs Th2 cell-mediated innate immunity in the developing lung.

Authors: Chen G, Wan H, Luo F, Zhang L, Xu Y, Lewkowich I, Wills-Karp M, Whitsett JA
Journal: J Immunol - Page No 6133 (Tue Jun 01 00:00:00 EDT 2010)
Volume (Year): 184 (2010)
Product Usage: -

Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume.

Authors: Zeidler-Erdely PC, Kashon ML, Battelli LA, Young SH, Erdely A, Roberts JR, Reynolds SH, Antonini JM
Journal: Part Fibre Toxicol - Page No 12 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year): 5 (2008)
Product Usage: -

The proteasome inhibitor bortezomib aggravates renal ischemia-reperfusion injury.

Authors: Huber JM, Tagwerker A, Heininger D, Mayer G, Rosenkranz AR, Eller K
Journal: Am J Physiol Renal Physiol - Page No F451 (Sat Aug 01 00:00:00 EDT 2009)
Volume (Year): 297 (2009)
Product Usage: -

Increased expression of cathepsins and obesity-induced proinflammatory cytokines in lacrimal glands of male NOD mouse.

Authors: Li X, Wu K, Edman M, Schenke-Layland K, MacVeigh-Aloni M, Janga SR, Schulz B, Hamm-Alvarez SF
Journal: Invest Ophthalmol Vis Sci - Page No 5019 (Fri Oct 01 00:00:00 EDT 2010)
Volume (Year): 51 (2010)
Product Usage: -

Central administration of lipopolysaccharide induces depressive-like behavior in vivo and activates brain indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures.

Authors: Fu X, Zunich SM, O'Connor JC, Kavelaars A, Dantzer R, Kelley KW
Journal: J Neuroinflammation - Page No 43 (Fri Jan 01 00:00:00 EST 2010)
Volume (Year): 7 (2010)
Product Usage: -

Interleukin-17 promotes early allograft inflammation.

Authors: Gorbacheva V, Fan R, Li X, Valujskikh A
Journal: Am J Pathol - Page No 1265 (Wed Sep 01 00:00:00 EDT 2010)
Volume (Year): 177 (2010)
Product Usage: -

IL-21 administration into the nostril alleviates murine allergic rhinitis.

Authors: Hiromura Y, Kishida T, Nakano H, Hama T, Imanishi J, Hisa Y, Mazda O
Journal: J Immunol - Page No 7157 (Thu Nov 15 00:00:00 EST 2007)
Volume (Year): 179 (2007)
Product Usage: -

Differential effects of rapamycin in anti-GBM glomerulonephritis.

Authors: Hochegger K, Jansky GL, Soleiman A, Wolf AM, Tagwerker A, Seger C, Griesmacher A, Mayer G, Rosenkranz AR
Journal: J Am Soc Nephrol - Page No 1520 (Fri Aug 01 00:00:00 EDT 2008)
Volume (Year): 19 (2008)
Product Usage: -

Effect of HeNe laser irradiation on extracellular matrix deposition and expression of cytokines and chemokines in paracoccidioidomycotic lesions.

Authors: Nagib PR, Gameiro J, da Costa TA, Di Gangi R, Ribeiro Jda S, Paulino LC, Verinaud L
Journal: Photochem Photobiol - Page No 920 (Thu Jul 01 00:00:00 EDT 2010)
Volume (Year): 86 (2010)
Product Usage: -

The effects of targeted deletion of cannabinoid receptors CB1 and CB2 on intranasal sensitization and challenge with adjuvant-free ovalbumin.

Authors: Kaplan BL, Lawver JE, Karmaus PW, Ngaotepprutaram T, Birmingham NP, Harkema JR, Kaminski NE
Journal: Toxicol Pathol - Page No 382 (Fri Jan 01 00:00:00 EST 2010)
Volume (Year): 38 (2010)
Product Usage: -

Interferon-gamma and tumor necrosis factor-alpha mediate the upregulation of indoleamine 2,3-dioxygenase and the induction of depressive-like behavior in mice in response to bacillus Calmette-Guerin.

Authors: O'Connor JC, Andre C, Wang Y, Lawson MA, Szegedi SS, Lestage J, Castanon N, Kelley KW, Dantzer R
Journal: J Neurosci - Page No 4200 (Wed Apr 01 00:00:00 EDT 2009)
Volume (Year): 29 (2009)
Product Usage: -

Induction of IDO by bacille Calmette-Guerin is responsible for development of murine depressive-like behavior.

Authors: O'Connor JC, Lawson MA, Andre C, Briley EM, Szegedi SS, Lestage J, Castanon N, Herkenham M, Dantzer R, Kelley KW
Journal: J Immunol - Page No 3202 (Sun Mar 01 00:00:00 EST 2009)
Volume (Year): 182 (2009)
Product Usage: -

Bradykinin inducible receptor is essential to lipopolysaccharide-induced acute lung injury in mice.

Authors: Campanholle G, Landgraf RG, Borducchi E, Semedo P, Wang PH, Amano MT, Russo M, Pacheco-Silva A, Jancar S, Camara NO
Journal: Eur J Pharmacol - Page No 132 (Tue May 25 00:00:00 EDT 2010)
Volume (Year): 634 (2010)
Product Usage: -

Psychological stress suppresses innate IFN-gamma production via glucocorticoid receptor activation: reversal by the anxiolytic chlordiazepoxide.

Authors: Curtin NM, Boyle NT, Mills KH, Connor TJ
Journal: Brain Behav Immun - Page No 535 (Fri May 01 00:00:00 EDT 2009)
Volume (Year): 23 (2009)
Product Usage: -

Orally administered lactoperoxidase ameliorates dextran sulfate sodium-induced colitis in mice by up-regulating colonic interleukin-10 and maintaining peripheral regulatory T cells.

Authors: Shin K, Horigome A, Yamauchi K, Yaeshima T, Iwatsuki K
Journal: Int Immunopharmacol - Page No 1387 (Sun Nov 01 00:00:00 EDT 2009)
Volume (Year): 9 (2009)
Product Usage: -

Role of alpha/beta and gamma/delta T cells in renal ischemia-reperfusion injury.

Authors: Hochegger K, Schatz T, Eller P, Tagwerker A, Heininger D, Mayer G, Rosenkranz AR
Journal: Am J Physiol Renal Physiol - Page No F741 (Sat Sep 01 00:00:00 EDT 2007)
Volume (Year): 293 (2007)
Product Usage: -

Both TLR2 and TLR4 are required for the effective immune response in Staphylococcus aureus-induced experimental murine brain abscess.

Authors: Stenzel W, Soltek S, Sanchez-Ruiz M, Akira S, Miletic H, Schluter D, Deckert M
Journal: Am J Pathol - Page No 132 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year): 172 (2008)
Product Usage: -

Interleukin-10 overexpression promotes Fas-ligand-dependent chronic macrophage-mediated demyelinating polyneuropathy.

Authors: Dace DS, Khan AA, Stark JL, Kelly J, Cross AH, Apte RS
Journal: Plos One - Page No e7121 (Thu Jan 01 00:00:00 EST 2009)
Volume (Year): 4 (2009)
Product Usage: -

Topical delivery of silver nanoparticles promotes wound healing.

Authors: Tian J, Wong KK, Ho CM, Lok CN, Yu WY, Che CM, Chiu JF, Tam PK
Journal: Chemmedchem - Page No 129 (Mon Jan 01 00:00:00 EST 2007)
Volume (Year): 2 (2007)
Product Usage: -

Early rise in inflammation and microcirculatory disorder determine the development of autoimmune pancreatitis in the MRL/Mp-mouse.

Authors: Sorg H, Lorch B, Jaster R, Fitzner B, Ibrahim S, Holzhueter SA, Nizze H, Vollmar B
Journal: Am J Physiol Gastrointest Liver Physiol - Page No G1274 (Mon Dec 01 00:00:00 EST 2008)
Volume (Year): 295 (2008)
Product Usage: -

Psychological stress reactivates dextran sulfate sodium-induced chronic colitis in mice.

Authors: Melgar S, Engstrom K, Jagervall A, Martinez V
Journal: Stress - Page No 348 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year): 11 (2008)
Product Usage: -

Bacterial lipopeptide triggers massive albuminuria in murine lupus nephritis by activating Toll-like receptor 2 at the glomerular filtration barrier.

Authors: Pawar RD, Castrezana-Lopez L, Allam R, Kulkarni OP, Segerer S, Radomska E, Meyer TN, Schwesinger CM, Akis N, Grone HJ, Anders HJ
Journal: Immunology - Page No e206 (Tue Sep 01 00:00:00 EDT 2009)
Volume (Year): 128 (2009)
Product Usage: -

Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function.

Authors: Morales-Tirado V, Sojka DK, Katzman SD, Lazarski CA, Finkelman FD, Urban JF, Fowell DJ
Journal: Blood - Page No 3498 (Thu Apr 29 00:00:00 EDT 2010)
Volume (Year): 115 (2010)
Product Usage: -

IL-17- and IFN-{gamma}-Secreting Foxp3+ T Cells Infiltrate the Target Tissue in Experimental Autoimmunity.

Authors: Esposito M, Ruffini F, Bergami A, Garzetti L, Borsellino G, Battistini L, Martino G, Furlan R
Journal: J Immunol - Page No 7467 (Wed Dec 15 00:00:00 EST 2010)
Volume (Year): 185 (2010)
Product Usage: -

Tumor necrosis factor-alpha: alternative role as an inhibitor of osteoclast formation in vitro.

Authors: Balga R, Wetterwald A, Portenier J, Dolder S, Mueller C, Hofstetter W
Journal: Bone - Page No 325 (Tue Aug 01 00:00:00 EDT 2006)
Volume (Year): 39 (2006)
Product Usage: -

Intravenous administration of MIP-1alpha with intra-tumor injection of P. acnes shows potent anti-tumor effect.

Authors: Nakano A, Yoneyama H, Ueha S, Kitabatake M, Ishikawa S, Kawase I, Sugiyama H, Matsushima K
Journal: Int Immunopharmacol - Page No 845 (Fri Jun 01 00:00:00 EDT 2007)
Volume (Year): 7 (2007)
Product Usage: -

CD4(+)CD25 (+) Regulatory T Cells Suppress Th17-Responses in an Experimental Colitis Model.

Authors: Ogino H, Nakamura K, Ihara E, Akiho H, Takayanagi R
Journal: Dig Dis Sci - Page No (Thu Jun 03 00:00:00 EDT 2010)
Volume (Year): (2010)
Product Usage: -

Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens.

Authors: Lech M, Kulkarni OP, Pfeiffer S, Savarese E, Krug A, Garlanda C, Mantovani A, Anders HJ
Journal: J Exp Med - Page No 1879 (Mon Aug 04 00:00:00 EDT 2008)
Volume (Year): 205 (2008)
Product Usage: -

Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses.

Authors: Allam R, Pawar RD, Kulkarni OP, Hornung V, Hartmann G, Segerer S, Akira S, Endres S, Anders HJ
Journal: Eur J Immunol - Page No 3487 (Mon Dec 01 00:00:00 EST 2008)
Volume (Year): 38 (2008)
Product Usage: -

Spatio-temporal differences in the profile of murine brain expression of proinflammatory cytokines and indoleamine 2,3-dioxygenase in response to peripheral lipopolysaccharide administration.

Authors: Andre C, O'Connor JC, Kelley KW, Lestage J, Dantzer R, Castanon N
Journal: J Neuroimmunol - Page No 90 (Sat Aug 30 00:00:00 EDT 2008)
Volume (Year): 200 (2008)
Product Usage: -

CD8 T cells producing IL-17 and IFN-gamma initiate the innate immune response required for responses to antigen skin challenge.

Authors: Kish DD, Li X, Fairchild RL
Journal: J Immunol - Page No 5949 (Fri May 15 00:00:00 EDT 2009)
Volume (Year): 182 (2009)
Product Usage: -

Beneficial effect of brewers' yeast extract on daily activity in a murine model of chronic fatigue syndrome.

Authors: Takahashi T, Yu F, Zhu SJ, Moriya J, Sumino H, Morimoto S, Yamaguchi N, Kanda T
Journal: Evid Based Complement Alternat Med - Page No 109 (Wed Mar 01 00:00:00 EST 2006)
Volume (Year): 3 (2006)
Product Usage: -

Differential roles of estrogen receptors alpha and beta in control of B cell maturation and selection(1).

Authors: Hill L, Venkatesh J, Chinnasamy P, Grimaldi C, Diamond B
Journal: Mol Med - Page No (Mon Nov 22 00:00:00 EST 2010)
Volume (Year): (2010)
Product Usage: -

CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-gamma-induced chemokines.

Authors: Van den Steen PE, Deroost K, Van Aelst I, Geurts N, Martens E, Struyf S, Nie CQ, Hansen DS, Matthys P, Van Damme J, Opdenakker G
Journal: Eur J Immunol - Page No 1082 (Tue Apr 01 00:00:00 EDT 2008)
Volume (Year): 38 (2008)
Product Usage: -

Topical omega-3 and omega-6 fatty acids for treatment of dry eye.

Authors: Rashid S, Jin Y, Ecoiffier T, Barabino S, Schaumberg DA, Dana MR
Journal: Arch Ophthalmol - Page No 219 (Fri Feb 01 00:00:00 EST 2008)
Volume (Year): 126 (2008)
Product Usage: -

IL-9 Production by Regulatory T Cells Recruits Mast Cells That Are Essential for Regulatory T Cell-Induced Immune Suppression.

Authors: Eller K, Wolf D, Huber JM, Metz M, Mayer G, McKenzie AN, Maurer M, Rosenkranz AR, Wolf AM
Journal: J Immunol - Page No (Mon Nov 29 00:00:00 EST 2010)
Volume (Year): (2010)
Product Usage: -

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins.

Authors: Veldhoen M, Hirota K, Westendorf AM, Buer J, Dumoutier L, Renauld JC, Stockinger B
Journal: Nature - Page No 106 (Thu May 01 00:00:00 EDT 2008)
Volume (Year): 453 (2008)
Product Usage: -

Impact of systemic histamine deficiency on the crosstalk between mammary adenocarcinoma and T cells.

Authors: Hegyesi H, Colombo L, Pallinger E, Toth S, Boer K, Molnar V, Falus A
Journal: J Pharmacol Sci - Page No 66 (Sat Sep 01 00:00:00 EDT 2007)
Volume (Year): 105 (2007)
Product Usage: -

IL-4(-/-) mice with lethal Mesocestoides corti infections--reduced Th2 cytokines and alternatively activated macrophages.

Authors: O'Connell AE, Kerepesi LA, Vandergrift GL, Herbert DR, VAN Winkle TJ, Hooper DC, Pearce EJ, Abraham D
Journal: Parasite Immunol - Page No 741 (Tue Dec 01 00:00:00 EST 2009)
Volume (Year): 31 (2009)
Product Usage: -

Suppression of proinflammatory cytokine production in macrophages by lansoprazole.

Authors: Hinoki A, Yoshimura K, Fujita K, Akita M, Ikeda R, Nagashima M, Nomura M, Satomi A
Journal: Pediatr Surg Int - Page No 915 (Wed Nov 01 00:00:00 EST 2006)
Volume (Year): 22 (2006)
Product Usage: -

Novel model of TH2-polarized chronic ileitis: the SAMP1 mouse.

Authors: McNamee EN, Wermers JD, Masterson JC, Collins CB, Lebsack MD, Fillon S, Robinson ZD, Grenawalt J, Lee JJ, Jedlicka P, Furuta GT, Rivera-Nieves J
Journal: Inflamm Bowel Dis - Page No 743 (Sat May 01 00:00:00 EDT 2010)
Volume (Year): 16 (2010)
Product Usage: -

The antidepressant venlafaxine ameliorates murine experimental autoimmune encephalomyelitis by suppression of pro-inflammatory cytokines.

Authors: Vollmar P, Nessler S, Kalluri SR, Hartung HP, Hemmer B
Journal: Int J Neuropsychopharmacol - Page No 525 (Fri May 01 00:00:00 EDT 2009)
Volume (Year): 12 (2009)
Product Usage: -

Vitamin D deficiency in mice impairs colonic antibacterial activity and predisposes to colitis.

Authors: Lagishetty V, Misharin AV, Liu NQ, Lisse TS, Chun RF, Ouyang Y, McLachlan SM, Adams JS, Hewison M
Journal: Endocrinology - Page No 2423 (Tue Jun 01 00:00:00 EDT 2010)
Volume (Year): 151 (2010)
Product Usage: -

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Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR1000010353.mm.1	NM_008337.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1000010353.mm.1	TC1000001452.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1000010355.mm.1	NM_008337.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1000010355.mm.1	TC1000001452.mm.1	MTA TC
Affymetrix Mouse Clariom S Array	PSR1000010354.mm.1	NM_008337.4	Refseq
Affymetrix Mouse Clariom S Array	PSR1000010354.mm.1	TC1000001452.mm.1	MTA TC

System Message

Genomic Map