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- Gene Symbol:
-
Top2a - Gene Name:
- topoisomerase (DNA) II alpha
- Gene Aliases:
- -
- Chromosome Location:
- Chr.10: 86901467 - 86930947 on Build Rnor_6.0
- Species:
- Rat
- Species Specific ID (Flybase ID):
- -
Genomic Map
Back To TopAssay Details
| Gene Symbol: Top2a | ||||||
|---|---|---|---|---|---|---|
| Interrogated Sequence | Translated Protein | Exon Boundary | Assay Location | IMAGE Clone ID | Amplicon Length | |
| RefSeq | NM_022183.2 | NP_071519.2 | 4 - 5 | 471 | 72 | |
| GenBank mRNA | Z19552.1 | - | 4 - 5 | 471 | 72 | |
Back To TopMore Information
Updated Mapping Information
This assay targets the same location as RTA transcript cluster(s) TC1000003726.rn.1Set Membership: |
Ambion siRNA available
Amplicon length between 71 and 85
Recommended Assay
Rattus norvegicus
1700
Inventoried
Probe spans exons
|
Matching Ambion siRNAs:
Panther Classification:
Gene Ontology Categories:
Function(s)
Process(es)
resolution of meiotic recombination intermediates
sister chromatid segregation
hematopoietic progenitor cell differentiation
DNA topological change
DNA ligation
DNA unwinding involved in DNA replication
mitotic recombination
cellular response to DNA damage stimulus
chromosome segregation
brain development
aging
cerebellar Purkinje cell differentiation
cerebellar granule cell differentiation
chromosome condensation
apoptotic chromosome condensation
embryonic cleavage
response to drug
regulation of circadian rhythm
positive regulation of apoptotic process
mitotic DNA integrity checkpoint
positive regulation of viral genome replication
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
response to parathyroid hormone
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
sequence-specific DNA binding
structure-specific DNA binding
poly(A) RNA binding
protein heterodimerization activity
resolution of meiotic recombination intermediates
sister chromatid segregation
hematopoietic progenitor cell differentiation
DNA topological change
DNA ligation
DNA unwinding involved in DNA replication
mitotic recombination
cellular response to DNA damage stimulus
chromosome segregation
brain development
aging
cerebellar Purkinje cell differentiation
cerebellar granule cell differentiation
chromosome condensation
apoptotic chromosome condensation
embryonic cleavage
response to drug
regulation of circadian rhythm
positive regulation of apoptotic process
mitotic DNA integrity checkpoint
positive regulation of viral genome replication
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
response to parathyroid hormone
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase activity
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
sequence-specific DNA binding
structure-specific DNA binding
poly(A) RNA binding
protein heterodimerization activity
MicroArray Probes:
Agilent
Affymetrix
ABI
| Array Name | Probe IDs | Targets | Target Type |
|---|---|---|---|
| Agilent Whole Rat Genome Microarray 4x44K v2 | A_44_P531770 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 58173 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 712013 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 484435 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 133694 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 837566 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 204078 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 735968 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 363142 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 541990 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 449871 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 266668 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 149274 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 799074 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 363578 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 10909 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 889061 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 949730 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 267366 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 319900 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 732730 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 114728 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 397317 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 1x1M | 389199 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 4x180K | 99759 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 4x180K | 34763 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 4x180K | 90939 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 4x180K | 145819 | - | - |
| Agilent SurePrint G3 Rat CGH Microarray 4x180K | 2091 | - | - |
| Agilent Whole Rat Genome Microarray 4x44K v3 | A_44_P531770 | - | - |
| Agilent Whole Rat Genome Microarray 4x44K v3 | A_44_P531770 | - | - |
| Agilent SurePrint G3 Rat GE 8x60K Microarray | A_44_P531770 | - | - |
| SurePrint G3 Rat Gene Expression Microarray G4131A | A_44_P531770 | - | - |
| SurePrint G3 Rat Gene Expression Microarray G4131A | A_43_P12148 | - | - |
| Agilent Rat Genome CGH Microarray 105A (G4436A) | 90276 | - | - |
| Agilent Rat Genome CGH Microarray 105A (G4436A) | 75771 | - | - |
| Agilent Rat Genome CGH Microarray 105A (G4436A) | 86747 | - | - |
| Array Name | Probe IDs | Targets | Target Type |
|---|---|---|---|
| Affymetrix Rat Gene 1.0 ST Array | 10746999 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747007 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746980 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746994 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746993 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746990 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746988 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746981 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746986 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747009 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747002 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747005 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746992 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746982 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747010 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746996 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746995 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747006 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746991 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746983 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747004 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747003 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746985 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746997 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747001 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746987 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747008 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746989 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10747000 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746978 | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746977 | - | - |
| Affymetrix Rat Gene 1.1 ST Array | 10746976 | - | - |
| Rat Genome 230 2.0 Array | 1372186_a_at | - | - |
| Rat Genome 230 2.0 Array | 1388650_at | - | - |
| Rat Genome 230 2.0 Array | 1369990_at | - | - |
| Rat Genome 230 2.0 Array | 1369990_PM_at | - | - |
| Rat Genome 230 2.0 Array | 1388650_PM_at | - | - |
| Rat Genome 230 2.0 Array | 1372186_PM_a_at | - | - |
| Affymetrix HT Rat Focus Array | 1369990_PM_at | - | - |
| Affymetrix HT Rat Focus Array | 1388650_PM_at | - | - |
| Affymetrix HT Rat Focus Array | 1372186_a_at | - | - |
| Affymetrix HT Rat Focus Array | 1372186_PM_a_at | - | - |
| Affymetrix HT Rat Focus Array | 1388650_at | - | - |
| Affymetrix HT Rat Focus Array | 1369990_at | - | - |
| Affymetrix Rat Clariom S Assay | PSR1000033367.rn.1 | TC1000003726.rn.1 | RTA TC |
| Rat Expression Set 230 | 1388650_PM_at | - | - |
| Rat Expression Set 230 | 1369990_at | - | - |
| Rat Expression Set 230 | 1369990_PM_at | - | - |
| Rat Expression Set 230 | 1388650_at | - | - |
| Rat Expression Set 230 | 1372186_PM_a_at | - | - |
| Rat Expression Set 230 | 1372186_a_at | - | - |
| Affymetrix Rat Gene 1.0 ST Array | 10746976 | - | - |
| Rat Genome U34 Set | rc_AA899854_at | - | - |
| Rat Genome U34 Set | Z19552cds_at | - | - |
| Rat Genome U34 Set | D14045_s_at | - | - |
| Rat Genome U34 Set | Z19552cds_at | - | - |
| Rat Genome U34 Set | D14045_s_at | - | - |
| Rat Genome U34 Set | rc_AA899854_at | - | - |
| Array Name | Probe IDs | Targets | Target Type |
|---|---|---|---|
| ABI Rat Genome Survey Microarray | 21135736 | - | - |
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