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          • Home
          • › Search Tool
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          • › Rn04244524_m1
          See other PTPN11 GE Assays ›
          Gene Symbol:
          Ptpn11
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 11
          Gene Aliases:
          Shp2
          Chromosome Location:
          Chr.12: 40895515 - 40955999 on Build Rnor_6.0
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          Assay ID Rn04244524_m1
          Best Coverage
          Size
          Availability Inventoried
          Catalog # 4331182
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: Ptpn11
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_001177593.1 NP_001171064.1 2 - 3 317 71
          NM_013088.2 NP_037220.2 2 - 3 317 71
          GenBank mRNA U05963.1 - 2 - 3 248 71
          U09307.1 - 2 - 3 242 71

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          More Information


          Updated Mapping Information

          This assay targets the same location as RTA transcript cluster(s) TC1200000673.rn.1

          Set Membership:

          Ambion siRNA available Amplicon length between 71 and 85 Protein Phosphatase Recommended Assay Rattus norvegicus Inventoried Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Ptpn11

          Panther Classification:

          Molecular Function -

          protein phosphatase

          Gene Ontology Categories:

          Function(s) Process(es)

          DNA damage checkpoint
          activation of MAPK activity
          protein dephosphorylation
          lipid metabolic process
          triglyceride metabolic process
          epidermal growth factor receptor signaling pathway
          integrin-mediated signaling pathway
          axonogenesis
          brain development
          heart development
          hormone-mediated signaling pathway
          positive regulation of signal transduction
          dephosphorylation
          platelet formation
          microvillus organization
          abortive mitotic cell cycle
          regulation of cell adhesion mediated by integrin
          negative regulation of cell adhesion mediated by integrin
          multicellular organism growth
          organ growth
          peptidyl-tyrosine dephosphorylation
          megakaryocyte development
          atrioventricular canal development
          ERBB signaling pathway
          regulation of multicellular organism growth
          hormone metabolic process
          glucose homeostasis
          positive regulation of mitotic cell cycle
          negative regulation of insulin secretion
          regulation of protein export from nucleus
          positive regulation of hormone secretion
          negative regulation of hormone secretion
          platelet-derived growth factor receptor signaling pathway
          neurotrophin TRK receptor signaling pathway
          ephrin receptor signaling pathway
          multicellular organismal reproductive process
          genitalia development
          inner ear development
          homeostasis of number of cells within a tissue
          negative regulation of cortisol secretion
          negative regulation of growth hormone secretion
          face morphogenesis
          intestinal epithelial cell migration
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of glucose import in response to insulin stimulus
          phosphoprotein phosphatase activity
          protein tyrosine phosphatase activity
          non-membrane spanning protein tyrosine phosphatase activity
          SH3/SH2 adaptor activity
          insulin receptor binding
          protein binding
          protein domain specific binding
          receptor tyrosine kinase binding
          D1 dopamine receptor binding
          phospholipase binding
          insulin receptor substrate binding
          peptide hormone receptor binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Rat Clariom S Assay PSR1200006106.rn.1 TC1200000673.rn.1 RTA TC
          Affymetrix Rat Clariom S Assay PSR1200006107.rn.1 TC1200000673.rn.1 RTA TC
          Affymetrix Rat Clariom S Assay PSR1200006108.rn.1 TC1200000673.rn.1 RTA TC

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