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Gibco
Human INSL5/INSL7 Recombinant Protein, PeproTech®
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Product Details
130-05-500UG
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
A-Chain: QDLQTLCCTD GCSMTDLSAL C B-Chain: RAAPYGVRLC GREFIRAVIF TCGGSRW
Molecular weight
5.2 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Conjugate
Form
Lyophilized
Amount
500 µg
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Human INSL5/INSL7 hybrid is a heterodimeric, 5.2 kDa protein consisting of a 27 amino acid beta-chain linked to a 21 amino acid alpha-chain by two disulfide bonds.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an insulin-like heterodimeric structure of two polypeptide chains held together by two inter-chain disulfide bonds. The INSL5/INSL7 hybrid contains the beta-chain of INSL7 (Relaxin-3), linked to the alpha-chain of INSL5. The INSL5/INSL7 hybrid protein can specifically activate the G protein-coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Insulin-like peptide 5; Insulin-like peptide 7; Insulin-like peptide INSL5; Insulin-like peptide INSL7; prepro-INSL5; Prorelaxin H3; Relaxin-3; zins4; similar to insulin
Gene Aliases: H3; INSL5; INSL7; PRO182; RLN3; RXN3; UNQ156; UNQ156/PRO182; UNQ6188/PRO20213; ZINS4
UniProt ID: (Human) Q9Y5Q6, (Human) Q8WXF3
Entrez Gene ID: (Human) 10022, (Human) 117579
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