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Gibco
Human MD-2/LY96 Recombinant Protein, PeproTech®
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Product Details
160-07-50UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
HEK293 cells
Amino acid sequence
QKQYWVCNSS DASISYTYCD KMQYPISINV NPCIELKGSK GLLHIFYIPR RDLKQLYFNL YITVNTMNLP KRKEVICRGS DDDYSFCRAL KGETVNTTIS FSFKGIKFSK GKYKCVVEAI SGSPEEMLFC LEFVILHQPN SNHHHHHH
Tag
His-tag
Molecular weight
17.2 kDa
Class
Recombinant
Type
Protein
Purity
≥ 90% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Human MD-2/LY96 demonstrates concentration-dependent ability to immobilize rhTLR4 in a functional ELISA
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
PeproTech's HEK293 cell-derived Recombinant Human MD-2/LY96 is a disulfide-linked homodimer whose monomer contains 148 amino acid residues, including a C-terminal His tag, and has a calculated molecular weight of 17.2 kDa.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
MD-2 is a gene that encodes a protein involved in the recognition of bacterial lipopolysaccharides (LPS) by the immune system. It is located on chromosome 8 and is part of a larger family of genes that encode for similar proteins. The MD-2 protein forms a complex with Toll-like receptor 4 (TLR4) to recognize and respond to LPS, triggering an immune response. Mutations or variations in the MD-2 gene have been associated with various diseases and conditions, including sepsis and inflammatory disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ESOP-1; Ly-96; Lymphocyte antigen 96; myeloid differentiation protein-2; Protein MD-2
Gene Aliases: ESOP-1; ESOP1; ly-96; LY96; MD-2; MD2
UniProt ID: (Human) Q9Y6Y9
Entrez Gene ID: (Human) 23643
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