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Gibco
Human Nesfatin-1 Recombinant Protein, PeproTech®
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Product Details
300-67-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
VPIDIDKTKV QNIHPVESAK IEPPDTGLYY DEYLKQVIDV LETDKHFREK LQKADIEEIK SGRLSKELDL VSHHVRTKLD EL
Molecular weight
9.7 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by an in vivo assay using healthy wild type male mice (C57BL/6J). Mice were treated via intraperitoneal injection once at a dose of 4ug Nesfatin-1/gm of body weight. Significant effects on body weight and food consumption were observed relative to saline-treated controls.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
300-67-1MG will be provided as 10 x 100 µg (300-67-100UG).
300-67-200UG will be provided as 2 x 100 µg (300-67-100UG).
300-67-500UG will be provided as 5 x 100 µg (300-67-100UG).
Recombinant Human Nesfatin-1 is a 9.7 kDa protein containing 82 amino acid residues.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
NUCB2 was initially identified as calcium-binding protein EF hand motif-containing protein that could bind with Necdin, a growth suppressor expressed primarily in postmitotic neurons. NUC2 is a secreted protein that is cleaved into three major peptide products, Nesfatin-1, Nesfatin-2, and Nesfatin-3, of which Nesfatin-1 has been found to cause the suppression of food intake in a leptin-independent manner. Other studies have suggested that NUCB2/Nesfatin-1 may also play roles in energy homeostasis and closely related neuroendocrine functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA-binding protein NEFA; Epididymis secretory protein Li 109; Gastric cancer antigen Zg4; nesfatin 1; nesfatin-1; Nucleobindin-2; Nucleobindin-2/Nesfatin-1; nucleobinding 2; prepronefastin; Prepronesfatin
Gene Aliases: HEL-S-109; NEFA; NUCB2
UniProt ID: (Human) P80303
Entrez Gene ID: (Human) 4925
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