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Gibco
Human TMIGD2/CD28H Fc Recombinant Protein, PeproTech®
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Product Details
310-42-250UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
CHO cells
Amino acid sequence
LSVQQGPNLL QVRQGSQATL VCQVDQATAW ERLRVKWTKD GAILCQPYIT NGSLSLGVCG PQGRLSWQAP SHLTLQLDPV SLNHSGAYVC WAAVEIPELE EAEGNITRLF VDPDDPTQNR NRIASFPGGG PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K
Tag
Fc-tag
Molecular weight
40.1 kDa
Class
Recombinant
Type
Protein
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to bind recombinant human B7-H7 protein in a functional ELISA.
Conjugate
Form
Lyophilized
Amount
250 µg
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
CHO cell-derived Recombinant Human TMGID2/CD28H Fc is a glycosylated, disulfide-linked homodimer of 361-amino-acid-residues whose monomer consists of the 128-amino-acid extracellular domain fused to the 231-amino-acid length Fc portion of human IgG1 by two glycine residues. The calculated molecular weight of monomeric Recombinant TMIGD2/CD28H Fc is 40.1kDa; however, due to glycosylation, it migrates at an apparent molecular weight of approximately 55-60 kDa by SDS-PAGE analysis under reducing conditions.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
TMIGD2 (transmembrane and immunoglobulin domain containing 1), also known as immunoglobulin-containing and proline-rich receptor 1 (IGPR1), is novel adhesion molecule that is expressed in multiple tissues, primarily in cells of epithelium and endothelium origins. TMIGD2 is thought to be involved in angiogenesis and regulates cellular morphology, homophilic cell aggregation, and cell-cell interaction. TMIGD2 activity also modulates actin stress fiber formation and focal adhesion and reduces cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD28 homolog; CD28 homologue; IGPR-1; Immunoglobulin and proline-rich receptor 1; immunoglobulin-containing and proline-rich receptor 1; TMIGD2; Transmembrane and immunoglobulin domain-containing protein 2
Gene Aliases: CD28H; IGPR-1; IGPR1; TMIGD2; UNQ3059/PRO9879
UniProt ID: (Human) Q96BF3
Entrez Gene ID: (Human) 126259
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