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Gibco
Rat IL-5 Recombinant Protein, PeproTech®
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Product Details
400-05-1MG
Applications
Tested Dilution
Publications
Product Specifications
Published species
Rat
Expression System
E. coli
Class
Recombinant
Type
Protein
Conjugate
Form
Lyophilized
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
400-05-1MG will be provided as 5 x 200 µg (400-05-200UG).
400-05-500UG will be provided as multiple 100 µg (400-05-100UG) and 200 µg (400-05-200UG) vials.
Recombinant Rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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