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          • Proteins & Peptides ›
          • FGF10 Proteins

          Gibco

          Rat FGF-10 Recombinant Protein, PeproTech®

          View all (6) FGF10 proteins

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          Cite Rat FGF-10 Recombinant Protein, PeproTech®

          Additional Information:
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          Product Details

          400-42-100UG

          Applications
          Tested Dilution
          Publications

          Control (Ctrl)

          Assay-dependent
          -

          Bioactivity (Bioactivity)

          Assay-dependent
          -
          Product Specifications

          Species

          Rat

          Expression System

          E. coli

          Amino acid sequence

          MQALGQDMVS PEATNSSSSS SSSSSSSSFS SPSSAGRHVR SYNHLQGDVR WRKLFSFTKY FLKIEKNGKV SGTKKENCPY SILEITSVEI GVVAVKAINS NYYLAMNKKG KLYGSKEFNN DCKLKERIEE NGYNTYASFN WQHNGRQMYV ALNGKGAPRR GQKTRRKNTS AHFLPMVVHS

          Molecular weight

          20.2 kDa

          Class

          Recombinant

          Type

          Protein

          Purity

          ≥ 95% by SDS-PAGE gel and HPLC analyses.

          Endotoxin concentration

          <1 EU/µg

          Activity

          Assay 1: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8). Assay 2: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 1-5 ng/ml.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Purification

          purified

          Contains

          no preservative

          Storage conditions

          -20°C

          Shipping conditions

          Ambient

          Product Specific Information

          Recombinant Rat FGF-10 is a 20.2 kDa protein consisting of 180 amino acid residues.

          This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

          Target Information

          FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FGF; FGF-10; Fibroblast growth factor; Fibroblast growth factor 10

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          Gene Aliases: FGF-10; Fgf10

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          UniProt ID: (Rat) P70492

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          Entrez Gene ID: (Rat) 25443

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          It has to be done as per old AB suggested Products section.
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