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Invitrogen
Bovine Factor V Native Protein
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Product Details
RP-43127
Product Specifications
Species
Bovine
Molecular weight
330 kDa
Class
Native
Type
Protein
Conjugate
Form
Liquid
Purification
SDS-PAGE
Storage buffer
50% water with 50% glycerol
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
RP-43127 contains native bovine Factor V protein.
RP-43127 may be used as a positive control in many immunological assays.
Target Information
Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activated protein C cofactor; Coagulation factor V; coagulation factor V (proaccelerin, labile factor); Factor 5; Factor5
Gene Aliases: F5
UniProt ID: (Bovine) Q28107
Entrez Gene ID: (Bovine) 280687
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