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Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144725. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Arf-GAP domain and FG repeat-containing protein 2; arf-GAP domain and FG repeats-containing protein 2; HIV-1 Rev-binding protein-like protein; nucleoporin; RAB-R; Rev/Rex activation domain binding protein-related; Rev/Rex activation domain-binding protein related
Gene Aliases: AGFG2; HRBL; RABR
UniProt ID: (Human) O95081
Entrez Gene ID: (Human) 3268
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