Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58032. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a member of the Rho guanine nucleotide exchange factor family. The encoded protein interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 190 kDa guanine nucleotide exchange factor; p190-RhoGEF; Rho guanine nucleotide exchange factor; Rho guanine nucleotide exchange factor (GEF) 28; Rho guanine nucleotide exchange factor 28; Rho interacting protein 2; rho-guanine nucleotide exchange factor
Gene Aliases: ARHGEF28; KIAA1998; p190RHOGEF; RGNEF; RIP2
UniProt ID: (Human) Q8N1W1
Entrez Gene ID: (Human) 64283
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