Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57263. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a Rho-like GTPase that switches between the active state and inactive state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy, also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cdc42 guanine nucleotide exchange factor (GEF) 9; Collybistin; hPEM-2 collybistin; PEM-2 homolog; Rac/Cdc42 guanine nucleotide exchange factor 9; Rho guanine nucleotide exchange factor 9
Gene Aliases: ARHDH9; ARHGEF9; COLLYBISTIN; EIEE8; HPEM-2; KIAA0424; PEM-2; PEM2
UniProt ID: (Human) O43307
Entrez Gene ID: (Human) 23229
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