Product References
TRPV1 regulates ApoE4-disrupted intracellular lipid homeostasis and decreases synaptic phagocytosis by microglia.
Experimental & molecular medicine
Wang C,Lu J,Sha X,Qiu Y,Chen H,Yu Z
350-02 was used in Cell Culture to suggest that TRPV1 regulation of lipid metabolism could be a therapeutic approach to alleviate the consequences of the ApoE4 allele.
Wed Feb 01 00:00:00 EST 2023
Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets.
Molecular & cellular proteomics : MCP
Tshilenge KT,Aguirre CG,Bons J,Gerencser AA,Basisty N,Song S,Rose J,Lopez-Ramirez A,Naphade S,Loureiro A,Battistoni E,Milani M,Wehrfritz C,Holtz A,Hetz C,Mooney SD,Schilling B,Ellerby LM
350-02 was used in Cell Culture to define the proteome of human Huntington's disease patient-derived medium-spiny projection neurons.
Mon May 01 00:00:00 EDT 2023
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.
EMBO molecular medicine
Emmenegger M,De Cecco E,Hruska-Plochan M,Eninger T,Schneider MM,Barth M,Tantardini E,de Rossi P,Bacioglu M,Langston RG,Kaganovich A,Bengoa-Vergniory N,Gonzalez-Guerra A,Avar M,Heinzer D,Reimann R,Häsler LM,Herling TW,Matharu NS,Landeck N,Luk K,Melki R,Kahle PJ,Hornemann S,Knowles TPJ,Cookson MR,Polymenidou M,Jucker M,Aguzzi A
Tue Sep 07 00:00:00 EDT 2021
APOE4 Affects Basal and NMDAR-Mediated Protein Synthesis in Neurons by Perturbing Calcium Homeostasis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ramakrishna S,Jhaveri V,Konings SC,Nawalpuri B,Chakraborty S,Holst B,Schmid B,Gouras GK,Freude KK,Muddashetty RS
350-02 was used in In vitro experiments to show that the defective protein synthesis mediated by APOE4 is closely linked to the perturbation of calcium homeostasis caused by APOE4 in neurons.
Wed Oct 20 00:00:00 EDT 2021
Protective anti-prion antibodies in human immunoglobulin repertoires.
EMBO molecular medicine
Senatore A,Frontzek K,Emmenegger M,Chincisan A,Losa M,Reimann R,Horny G,Guo J,Fels S,Sorce S,Zhu C,George N,Ewert S,Pietzonka T,Hornemann S,Aguzzi A
Mon Sep 07 00:00:00 EDT 2020
Tailored Lipoprotein-Like miRNA Delivery Nanostructure Suppresses Glioma Stemness and Drug Resistance through Receptor-Stimulated Macropinocytosis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jiang G,Chen H,Huang J,Song Q,Chen Y,Gu X,Jiang Z,Huang Y,Lin Y,Feng J,Jiang J,Bao Y,Zheng G,Chen J,Chen H,Gao X
Sun Mar 01 00:00:00 EST 2020
Tailored Lipoprotein-Like miRNA Delivery Nanostructure Suppresses Glioma Stemness and Drug Resistance through Receptor-Stimulated Macropinocytosis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jiang G,Chen H,Huang J,Song Q,Chen Y,Gu X,Jiang Z,Huang Y,Lin Y,Feng J,Jiang J,Bao Y,Zheng G,Chen J,Chen H,Gao X
Sun Mar 01 00:00:00 EST 2020
Glycolaldehyde is an endogenous source of lysine N-pyrrolation.
The Journal of biological chemistry
Chikazawa M,Yoshitake J,Lim SY,Iwata S,Negishi L,Shibata T,Uchida K
Fri May 29 00:00:00 EDT 2020
Glycolaldehyde is an endogenous source of lysine N-pyrrolation.
The Journal of biological chemistry
Chikazawa M,Yoshitake J,Lim SY,Iwata S,Negishi L,Shibata T,Uchida K
Fri May 29 00:00:00 EDT 2020
Apolipoprotein E is a concentration-dependent pulmonary danger signal that activates the NLRP3 inflammasome and IL-1β secretion by bronchoalveolar fluid macrophages from asthmatic subjects.
The Journal of allergy and clinical immunology
Gordon EM,Yao X,Xu H,Karkowsky W,Kaler M,Kalchiem-Dekel O,Barochia AV,Gao M,Keeran KJ,Jeffries KR,Levine SJ
350-02 was used in In vitro experiments to investigate APOE regulation of IL-1β secretion.
Thu Aug 01 00:00:00 EDT 2019
ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance.
Journal of lipid research
Ramms B,Patel S,Nora C,Pessentheiner AR,Chang MW,Green CR,Golden GJ,Secrest P,Krauss RM,Metallo CM,Benner C,Alexander VJ,Witztum JL,Tsimikas S,Esko JD,Gordts PLSM
Thu Aug 01 00:00:00 EDT 2019