Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (32%), Rat (32%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145161. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BNP-32; Brain natriuretic factor prohormone; brain type natriuretic peptide; Gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide precursor B; Natriuretic peptides B; natriuretic protein; preproBNP
Gene Aliases: BNP; NPPB
UniProt ID: (Human) P16860
Entrez Gene ID: (Human) 4879
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