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Invitrogen
Human Bcl-B Synthetic Peptide
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Product Details
PEP-0353
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human LSD1.
PEP-0353 can be used as a blocking peptide with polyclonal antibody PA5-20234.
Target Information
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anti-apoptotic protein Boo; Anti-apoptotic protein NrH; Apoptosis regulator Bcl-B; Bcl-2-like protein 10; BCL2 family protein; Boo-like; Bcl2-L-10; BCL2-like 10 (apoptosis facilitator); death inducer binding to vBcl-2 and Apaf-1
Gene Aliases: BCL-B; bcl2-L-10; BCL2L10; BCLB; BOO; DIVA
UniProt ID: (Human) Q9HD36
Entrez Gene ID: (Human) 10017
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