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Product Details
PEP-1026
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Dry ice
Product Specific Information
This peptide corresponds to 18 amino acids near the carboxy terminus of human CAZIP.
PEP-1026 can be used as a blocking peptide with polyclonal antibody PA5-20912.
Target Information
CAZIP, also known as TIP150, contains a leucine-zipper domain at the C-terminus and has at least three isoforms. CAZIP is expressed in heart during early cardiac development and in parts of the nervous system in later embryonic development. It is thought to bind microtubules and facilitate the end-binding protein 1 (EB1)-dependent loading of MCAK onto microtubules plus ends and orchestrates the dynamics at the plus end of microtubules. CAZIP may regulate the dynamics of microtubules at their growing distal tip.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: +TIP of 150 kDa; Cardiac zipper protein; Microtubule plus-end tracking protein TIP150; Microtubule-associated tumor suppressor candidate 2; RP11-274A8.2; Tracking protein of 150 kDa
Gene Aliases: CAZIP; ICIS; KIAA0774; MTUS2; TIP150
UniProt ID: (Human) Q5JR59
Entrez Gene ID: (Human) 23281
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