Product References
Receptor transfer between immune cells by autoantibody-enhanced, CD32-driven trogocytosis is hijacked by HIV-1 to infect resting CD4 T cells.
Cell reports. Medicine
Albanese M,Chen HR,Gapp M,Muenchhoff M,Yang HH,Peterhoff D,Hoffmann K,Xiao Q,Ruhle A,Ambiel I,Schneider S,Mejías-Pérez E,Stern M,Wratil PR,Hofmann K,Amann L,Jocham L,Fuchs T,Ulivi AF,Besson-Girard S,Weidlich S,Schneider J,Spinner CD,Sutter K,Dittmer U,Humpe A,Baumeister P,Wieser A,Rothenfusser S,Bogner J,Roider J,Knolle P,Hengel H,Wagner R,Laketa V,Fackler OT,Keppler OT
300-06 was used in Cell migration to report that surface receptors can be transferred from primary macrophages to CD4 T cells and identify the Fcγ receptor CD32 as driver and cargo of this trogocytotic transfer.
Tue Apr 16 00:00:00 EDT 2024
Ly6Chi Monocytes Are Metabolically Reprogrammed in the Blood during Inflammatory Stimulation and Require Intact OxPhos for Chemotaxis and Monocyte to Macrophage Differentiation.
Cells
Purvis GSD,McNeill E,Wright B,Channon KM,Greaves DR
300-06 was used in Cell Culture to investigate the origin and transcriptional reprogramming of monocytes using a model of acute inflammation, zymosan-induced peritonitis.
Sun May 26 00:00:00 EDT 2024
Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFα Receptors in Human Triple-Negative Breast Cancer.
Cancers
Baram T,Oren N,Erlichman N,Meshel T,Ben-Baruch A
300-06 was used in Enzyme-linked immunosorbent assay to suggest that in addition to its immune-suppressive activities, PD-L1 may promote disease course in TNBC by inhibiting the protective effects of sTNFR1 and sTNFR2.
Tue Jul 19 00:00:00 EDT 2022
Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes.
Cancers
Erlichman N,Baram T,Meshel T,Morein D,Da'adoosh B,Ben-Baruch A
300-06 was used in Enzyme-linked immunosorbent assay to investigate the role of WT-PD-L1 in triple-negative breast cancer.
Fri Feb 18 00:00:00 EST 2022
Selective targeting of ligand-dependent and -independent signaling by GPCR conformation-specific anti-US28 intrabodies.
Nature communications
De Groof TWM,Bergkamp ND,Heukers R,Giap T,Bebelman MP,Goeij-de Haas R,Piersma SR,Jimenez CR,Garcia KC,Ploegh HL,Siderius M,Smit MJ
Fri Jul 16 00:00:00 EDT 2021
TNF-α Regulated Endometrial Stroma Secretome Promotes Trophoblast Invasion.
Frontiers in immunology
You Y,Stelzl P,Joseph DN,Aldo PB,Maxwell AJ,Dekel N,Liao A,Whirledge S,Mor G
300-06 was used in In vitro experiments to provide a new insight into the complexity of the implantation process and reveal the importance of inflammation for embryo implantation.
Fri Dec 24 00:00:00 EST 2021
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators.
Nature communications
Gurusamy M,Tischner D,Shao J,Klatt S,Zukunft S,Bonnavion R,Günther S,Siebenbrodt K,Kestner RI,Kuhlmann T,Fleming I,Offermanns S,Wettschureck N
Tue Nov 23 00:00:00 EST 2021
Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration.
Nature communications
Ofir-Birin Y,Ben Ami Pilo H,Cruz Camacho A,Rudik A,Rivkin A,Revach OY,Nir N,Block Tamin T,Abou Karam P,Kiper E,Peleg Y,Nevo R,Solomon A,Havkin-Solomon T,Rojas A,Rotkopf R,Porat Z,Avni D,Schwartz E,Zillinger T,Hartmann G,Di Pizio A,Quashie NB,Dikstein R,Gerlic M,Torrecilhas AC,Levy C,Nolte-'t Hoen ENM,Bowie AG,Regev-Rudzki N
Wed Aug 11 00:00:00 EDT 2021
SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms.
Scientific reports
Wang Y,Mohseni M,Grauel A,Diez JE,Guan W,Liang S,Choi JE,Pu M,Chen D,Laszewski T,Schwartz S,Gu J,Mansur L,Burks T,Brodeur L,Velazquez R,Kovats S,Pant B,Buruzula G,Deng E,Chen JT,Sari-Sarraf F,Dornelas C,Varadarajan M,Yu H,Liu C,Lim J,Hao HX,Jiang X,Malamas A,LaMarche MJ,Geyer FC,McLaughlin M,Costa C,Wagner J,Ruddy D,Jayaraman P,Kirkpatrick ND,Zhang P,Iartchouk O,Aardalen K,Cremasco V,Dranoff G,Engelman JA,Silver S,Wang H,Hastings WD,Goldoni S
Thu Jan 14 00:00:00 EST 2021
Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer.
Nature communications
Wang W,Tang YA,Xiao Q,Lee WC,Cheng B,Niu Z,Oguz G,Feng M,Lee PL,Li B,Yang ZH,Chen YF,Lan P,Wu XJ,Yu Q
Wed Jul 21 00:00:00 EDT 2021
Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer.
Nature communications
Wang W,Tang YA,Xiao Q,Lee WC,Cheng B,Niu Z,Oguz G,Feng M,Lee PL,Li B,Yang ZH,Chen YF,Lan P,Wu XJ,Yu Q
Wed Jul 21 00:00:00 EDT 2021
CCL5 mediates target-kinase independent resistance to FLT3 inhibitors in FLT3-ITD-positive AML.
Molecular oncology
Waldeck S,Rassner M,Keye P,Follo M,Herchenbach D,Endres C,Charlet A,Andrieux G,Salzer U,Boerries M,Duyster J,von Bubnoff N
Wed Apr 01 00:00:00 EDT 2020
MOSPD2 is a therapeutic target for the treatment of CNS inflammation.
Clinical and experimental immunology
Yacov N,Kafri P,Salem Y,Propheta-Meiran O,Feldman B,Breitbart E,Mendel I
300-06 was used in In vitro experiments to study the therapeutic potential of MOSPD2 in central nervous system disease.
Sat Aug 01 00:00:00 EDT 2020
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Cell death & disease
Huang R,Wang S,Wang N,Zheng Y,Zhou J,Yang B,Wang X,Zhang J,Guo L,Wang S,Chen Z,Wang Z,Xiang S
Thu Apr 16 00:00:00 EDT 2020
Infiltrating CD4+ T cells attenuate chemotherapy sensitivity in prostate cancer via CCL5 signaling.
The Prostate
Xiang P,Jin S,Yang Y,Sheng J,He Q,Song Y,Yu W,Hu S,Jin J
Sat Jun 01 00:00:00 EDT 2019
Chemokines as the modulators of endometrial epithelial cells remodelling.
Scientific reports
Złotkowska A,Andronowska A
Tue Sep 10 00:00:00 EDT 2019
Chemokines as the modulators of endometrial epithelial cells remodelling.
Scientific reports
Złotkowska A,Andronowska A
Tue Sep 10 00:00:00 EDT 2019
Cell Type-Specific Interferon-γ-mediated Antagonism of KSHV Lytic Replication.
Scientific reports
Park MK,Cho H,Roh SW,Kim SJ,Myoung J
Wed Feb 20 00:00:00 EST 2019
Notch-Mediated Tumor-Stroma-Inflammation Networks Promote Invasive Properties and CXCL8 Expression in Triple-Negative Breast Cancer.
Frontiers in immunology
Liubomirski Y,Lerrer S,Meshel T,Morein D,Rubinstein-Achiasaf L,Sprinzak D,Wiemann S,Körner C,Ehrlich M,Ben-Baruch A
300-06 was used in Enzyme-linked immunosorbent assay to investigate pro-metastatic chemokines in triple-negative breast cancer.
Thu Oct 01 00:00:00 EDT 2020
Tumor-Stroma-Inflammation Networks Promote Pro-metastatic Chemokines and Aggressiveness Characteristics in Triple-Negative Breast Cancer.
Frontiers in immunology
Liubomirski Y,Lerrer S,Meshel T,Rubinstein-Achiasaf L,Morein D,Wiemann S,Körner C,Ben-Baruch A
300-06 was used in Enzyme-linked immunosorbent assay to study the impact of tumor-stroma-inflammation networks on pro-metastatic phenotypes in triple-negative breast cancer (TNBC) to identify a novel tumor-stroma-inflammation networks that may promote TNBC aggressiveness by increasing the pro-malignancy potential of the TME and of the tumor cells themselves, and reveal key roles for CXCL8 in mediating these metastasis-promoting activities.
Mon Aug 10 00:00:00 EDT 2020
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
The Journal of biological chemistry
Lee AW,Deruaz M,Lynch C,Davies G,Singh K,Alenazi Y,Eaton JRO,Kawamura A,Shaw J,Proudfoot AEI,Dias JM,Bhattacharya S
Fri Jul 19 00:00:00 EDT 2019
The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth.
Oncogene
Heukers R,Fan TS,de Wit RH,van Senten JR,De Groof TWM,Bebelman MP,Lagerweij T,Vieira J,de Munnik SM,Smits-de Vries L,van Offenbeek J,Rahbar A,van Hoorick D,Söderberg-Naucler C,Würdinger T,Leurs R,Siderius M,Vischer HF,Smit MJ
Sun Jul 01 00:00:00 EDT 2018
Soluble PD-1 ligands regulate T-cell function in Waldenstrom macroglobulinemia.
Blood advances
Jalali S,Price-Troska T,Paludo J,Villasboas J,Kim HJ,Yang ZZ,Novak AJ,Ansell SM
Tue Aug 14 00:00:00 EDT 2018
Novel Anti-Inflammatory Peptides Based on Chemokine-Glycosaminoglycan Interactions Reduce Leukocyte Migration and Disease Severity in a Model of Rheumatoid Arthritis.
Journal of immunology (Baltimore, Md. : 1950)
McNaughton EF,Eustace AD,King S,Sessions RB,Kay A,Farris M,Broadbridge R,Kehoe O,Kungl AJ,Middleton J
Tue May 01 00:00:00 EDT 2018
Modulation of double-stranded RNA pattern recognition receptor signaling in ovarian cancer cells promotes inflammatory queues.
Oncotarget
Muccioli M,Nandigam H,Loftus T,Singh M,Venkatesh A,Wright J,Pate M,McCall K,Benencia F
300-06 was used in Enzyme-linked immunosorbent assay to investigate the potential of mouse and human ovarian cancer cells to produce inflammatory factors in response to pathogen recognition receptor signalling.
Fri Nov 30 00:00:00 EST 2018
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
Scientific reports
Alenazi Y,Singh K,Davies G,Eaton JRO,Elders P,Kawamura A,Bhattacharya S
Fri Apr 20 00:00:00 EDT 2018
Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets.
Journal of cellular physiology
Buskermolen JK,Roffel S,Gibbs S
Wed Nov 01 00:00:00 EDT 2017
A new antagonist for CCR4 attenuates allergic lung inflammation in a mouse model of asthma.
Scientific reports
Zhang Y,Wu Y,Qi H,Xiao J,Gong H,Zhang Y,Xu E,Li S,Ma D,Wang Y,Li W,Shen H
Wed Nov 08 00:00:00 EST 2017
Dual Function of Ccr5 during Langat Virus Encephalitis: Reduction in Neutrophil-Mediated Central Nervous System Inflammation and Increase in T Cell-Mediated Viral Clearance.
Journal of immunology (Baltimore, Md. : 1950)
Michlmayr D,Bardina SV,Rodriguez CA,Pletnev AG,Lim JK
Wed Jun 01 00:00:00 EDT 2016
NAP-2 Secreted by Human NK Cells Can Stimulate Mesenchymal Stem/Stromal Cell Recruitment.
Stem cell reports
Almeida CR,Caires HR,Vasconcelos DP,Barbosa MA
Tue Apr 12 00:00:00 EDT 2016
CCR5/CD4/CXCR4 oligomerization prevents HIV-1 gp120IIIB binding to the cell surface.
Proceedings of the National Academy of Sciences of the United States of America
Martínez-Muñoz L,Barroso R,Dyrhaug SY,Navarro G,Lucas P,Soriano SF,Vega B,Costas C,Muñoz-Fernández MÁ,Santiago C,Rodríguez Frade JM,Franco R,Mellado M
Tue May 13 00:00:00 EDT 2014
Eosinophils regulate peripheral B cell numbers in both mice and humans.
Journal of immunology (Baltimore, Md. : 1950)
Wong TW,Doyle AD,Lee JJ,Jelinek DF
Tue Apr 15 00:00:00 EDT 2014
Synaptic release of CCL5 storage vesicles triggers CXCR4 surface expression promoting CTL migration in response to CXCL12.
Journal of immunology (Baltimore, Md. : 1950)
Franciszkiewicz K,Boutet M,Gauthier L,Vergnon I,Peeters K,Duc O,Besse B,de Saint Basile G,Chouaib S,Mami-Chouaib F
Sat Nov 15 00:00:00 EST 2014
PC3-secreted microprotein is a novel chemoattractant protein and functions as a high-affinity ligand for CC chemokine receptor 2.
Journal of immunology (Baltimore, Md. : 1950)
Pei X,Sun Q,Zhang Y,Wang P,Peng X,Guo C,Xu E,Zheng Y,Mo X,Ma J,Chen D,Zhang Y,Zhang Y,Song Q,Guo S,Shi T,Zhang Z,Ma D,Wang Y
Sat Feb 15 00:00:00 EST 2014
Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry.
The Journal of biological chemistry
Jin J,Colin P,Staropoli I,Lima-Fernandes E,Ferret C,Demir A,Rogée S,Hartley O,Randriamampita C,Scott MG,Marullo S,Sauvonnet N,Arenzana-Seisdedos F,Lagane B,Brelot A
Fri Jul 04 00:00:00 EDT 2014
Regulation of T cell proliferation by JMJD6 and PDGF-BB during chronic hepatitis B infection.
Scientific reports
Chen CF,Feng X,Liao HY,Jin WJ,Zhang J,Wang Y,Gong LL,Liu JJ,Yuan XH,Zhao BB,Zhang D,Chen GF,Wan Y,Guo J,Yan HP,He YW
Mon Sep 15 00:00:00 EDT 2014
Adam8 limits the development of allergic airway inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950)
Knolle MD,Nakajima T,Hergrueter A,Gupta K,Polverino F,Craig VJ,Fyfe SE,Zahid M,Permaul P,Cernadas M,Montano G,Tesfaigzi Y,Sholl L,Kobzik L,Israel E,Owen CA
Sat Jun 15 00:00:00 EDT 2013
A chemokine self-presentation mechanism involving formation of endothelial surface microstructures.
Journal of immunology (Baltimore, Md. : 1950)
Whittall C,Kehoe O,King S,Rot A,Patterson A,Middleton J
Fri Feb 15 00:00:00 EST 2013
Glucagon-like peptide-1(9-36) inhibits chemokine-induced migration of human CD4-positive lymphocytes.
PloS one
Liberman A,Esser M,Marx N,Burgmaier M
Tue Aug 27 00:00:00 EDT 2013
Mesenchymal stem cells enhance ovarian cancer cell infiltration through IL6 secretion in an amniochorionic membrane based 3D model.
Journal of translational medicine
Touboul C,Lis R,Al Farsi H,Raynaud CM,Warfa M,Althawadi H,Mery E,Mirshahi M,Rafii A
Thu Jan 31 00:00:00 EST 2013
Biased and constitutive signaling in the CC-chemokine receptor CCR5 by manipulating the interface between transmembrane helices 6 and 7.
The Journal of biological chemistry
Steen A,Thiele S,Guo D,Hansen LS,Frimurer TM,Rosenkilde MM
Fri May 03 00:00:00 EDT 2013
Neutralizing nanobodies targeting diverse chemokines effectively inhibit chemokine function.
The Journal of biological chemistry
Blanchetot C,Verzijl D,Mujić-Delić A,Bosch L,Rem L,Leurs R,Verrips CT,Saunders M,de Haard H,Smit MJ
Fri Aug 30 00:00:00 EDT 2013
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
The Journal of experimental medicine
Yang D,Postnikov YV,Li Y,Tewary P,de la Rosa G,Wei F,Klinman D,Gioannini T,Weiss JP,Furusawa T,Bustin M,Oppenheim JJ
Mon Jan 16 00:00:00 EST 2012
A role for microRNA-155 modulation in the anti-HIV-1 effects of Toll-like receptor 3 stimulation in macrophages.
PLoS pathogens
Swaminathan G,Rossi F,Sierra LJ,Gupta A,Navas-Martín S,Martín-García J
Sat Sep 01 00:00:00 EDT 2012
Downregulation of the AU-rich RNA-binding protein ZFP36 in chronic HBV patients: implications for anti-inflammatory therapy.
PloS one
Jin WJ,Chen CF,Liao HY,Gong LL,Yuan XH,Zhao BB,Zhang D,Feng X,Liu JJ,Wang Y,Chen GF,Yan HP,He YW
Mon Aug 20 00:00:00 EDT 2012
CCL5 and CCR5 interaction promotes cell motility in human osteosarcoma.
PloS one
Wang SW,Wu HH,Liu SC,Wang PC,Ou WC,Chou WY,Shen YS,Tang CH
Wed Oct 17 00:00:00 EDT 2012
US28 is a potent activator of phospholipase C during HCMV infection of clinically relevant target cells.
PloS one
Miller WE,Zagorski WA,Brenneman JD,Avery D,Miller JL,O'Connor CM
Wed May 22 00:00:00 EDT 2013
US28 is a potent activator of phospholipase C during HCMV infection of clinically relevant target cells.
PloS one
Miller WE,Zagorski WA,Brenneman JD,Avery D,Miller JL,O'Connor CM
Wed May 22 00:00:00 EDT 2013
Chemoattractant-induced signaling via the Ras-ERK and PI3K-Akt networks, along with leukotriene C4 release, is dependent on the tyrosine kinase Lyn in IL-5- and IL-3-primed human blood eosinophils.
Journal of immunology (Baltimore, Md. : 1950)
Zhu Y,Bertics PJ
Sat Jan 01 00:00:00 EST 2011
Sequence similarity between the erythrocyte binding domain 1 of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV-1 strain MN reveals binding residues for the Duffy Antigen Receptor for Chemokines.
Virology journal
Bolton MJ,Garry RF
Mon Jan 31 00:00:00 EST 2011
Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin.
PloS one
Greene TA,Alarcon S,Thomas A,Berdougo E,Doranz BJ,Breslin PA,Rucker JB
Fri Sep 23 00:00:00 EDT 2011
Host chemokines bind to Staphylococcus aureus and stimulate protein A release.
The Journal of biological chemistry
Yung SC,Parenti D,Murphy PM
Fri Feb 18 00:00:00 EST 2011
GLI2 transcription factor mediates cytokine cross-talk in the tumor microenvironment.
The Journal of biological chemistry
Elsawa SF,Almada LL,Ziesmer SC,Novak AJ,Witzig TE,Ansell SM,Fernandez-Zapico ME
Fri Jun 17 00:00:00 EDT 2011
Why CCR2 and CCR5 blockade failed and why CCR1 blockade might still be effective in the treatment of rheumatoid arthritis.
PloS one
Lebre MC,Vergunst CE,Choi IY,Aarrass S,Oliveira AS,Wyant T,Horuk R,Reedquist KA,Tak PP
Fri Nov 04 00:00:00 EDT 2011
Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach.
The Journal of biological chemistry
Thiele S,Steen A,Jensen PC,Mokrosinski J,Frimurer TM,Rosenkilde MM
Fri Oct 28 00:00:00 EDT 2011
Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.
Blood
Tewary P,Yang D,de la Rosa G,Li Y,Finn MW,Krensky AM,Clayberger C,Oppenheim JJ
Thu Nov 04 00:00:00 EDT 2010
Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection.
PLoS pathogens
Crawford MA,Burdick MD,Glomski IJ,Boyer AE,Barr JR,Mehrad B,Strieter RM,Hughes MA
Thu Nov 18 00:00:00 EST 2010
PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection.
PLoS pathogens
Hanley TM,Blay Puryear W,Gummuluru S,Viglianti GA
Thu Jul 01 00:00:00 EDT 2010
Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.
Journal of immunology (Baltimore, Md. : 1950)
Rius C,Abu-Taha M,Hermenegildo C,Piqueras L,Cerda-Nicolas JM,Issekutz AC,Estañ L,Cortijo J,Morcillo EJ,Orallo F,Sanz MJ
Wed Sep 15 00:00:00 EDT 2010
Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.
Journal of immunology (Baltimore, Md. : 1950)
Rius C,Abu-Taha M,Hermenegildo C,Piqueras L,Cerda-Nicolas JM,Issekutz AC,Estañ L,Cortijo J,Morcillo EJ,Orallo F,Sanz MJ
Wed Sep 15 00:00:00 EDT 2010
Pan-CC chemokine neutralization restricts splenocyte egress and reduces inflammation in a model of arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Buatois V,Fagète S,Magistrelli G,Chatel L,Fischer N,Kosco-Vilbois MH,Ferlin WG
Sun Aug 15 00:00:00 EDT 2010
Role of the CXCR4/CXCL12 axis in lymphangioleiomyomatosis and angiomyolipoma.
Journal of immunology (Baltimore, Md. : 1950)
Clements D,Markwick LJ,Puri N,Johnson SR
Sun Aug 01 00:00:00 EDT 2010
Chemokine scavenger D6 is expressed by trophoblasts and aids the survival of mouse embryos transferred into allogeneic recipients.
Journal of immunology (Baltimore, Md. : 1950)
Madigan J,Freeman DJ,Menzies F,Forrow S,Nelson SM,Young A,Sharkey A,Moffett A,Graham GJ,Greer IA,Rot A,Nibbs RJ
Mon Mar 15 00:00:00 EDT 2010
Neurokinin-1 receptor (NK1-R) expression in the brains of SIV-infected rhesus macaques: implications for substance P in NK1-R immune cell trafficking into the CNS.
The American journal of pathology
Vinet-Oliphant H,Alvarez X,Buza E,Borda JT,Mohan M,Aye PP,Tuluc F,Douglas SD,Lackner AA
300-06 was used in Cell migration to demonstrate that treatment of monocytes with SP elicited changes in cell-surface expression for CCR5 and NK1-R in a dose-dependent manner.
Wed Sep 01 00:00:00 EDT 2010
Dynamic interaction networks in a hierarchically organized tissue.
Molecular systems biology
Kirouac DC,Ito C,Csaszar E,Roch A,Yu M,Sykes EA,Bader GD,Zandstra PW
Tue Oct 05 00:00:00 EDT 2010
Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice.
Nature medicine
Koenen RR,von Hundelshausen P,Nesmelova IV,Zernecke A,Liehn EA,Sarabi A,Kramp BK,Piccinini AM,Paludan SR,Kowalska MA,Kungl AJ,Hackeng TM,Mayo KH,Weber C
Thu Jan 01 00:00:00 EST 2009
HIV-1 gp120-induced migration of dendritic cells is regulated by a novel kinase cascade involving Pyk2, p38 MAP kinase, and LSP1.
Blood
Anand AR,Prasad A,Bradley RR,Deol YS,Nagaraja T,Ren X,Terwilliger EF,Ganju RK
Thu Oct 22 00:00:00 EDT 2009
HIV-1 Tat and heparan sulfate proteoglycan interaction: a novel mechanism of lymphocyte adhesion and migration across the endothelium.
Blood
Urbinati C,Nicoli S,Giacca M,David G,Fiorentini S,Caruso A,Alfano M,Cassetta L,Presta M,Rusnati M
Thu Oct 08 00:00:00 EDT 2009
Substance P (SP) enhances CCL5-induced chemotaxis and intracellular signaling in human monocytes, which express the truncated neurokinin-1 receptor (NK1R).
Journal of leukocyte biology
Chernova I,Lai JP,Li H,Schwartz L,Tuluc F,Korchak HM,Douglas SD,Kilpatrick LE
300-06 was used in In vitro experiments to identify an interaction among SP, NK1R, and HIV viral strains that use the chemokine receptor CCR5 as a coreceptor, suggesting crosstalk between NK1R and CCR5.
Thu Jan 01 00:00:00 EST 2009
Menopause and ovariectomy cause a low grade of systemic inflammation that may be prevented by chronic treatment with low doses of estrogen or losartan.
Journal of immunology (Baltimore, Md. : 1950)
Abu-Taha M,Rius C,Hermenegildo C,Noguera I,Cerda-Nicolas JM,Issekutz AC,Jose PJ,Cortijo J,Morcillo EJ,Sanz MJ
Wed Jul 15 00:00:00 EDT 2009
Significance of N-terminal proteolysis of CCL14a to activity on the chemokine receptors CCR1 and CCR5 and the human cytomegalovirus-encoded chemokine receptor US28.
Journal of immunology (Baltimore, Md. : 1950)
Richter R,Casarosa P,Ständker L,Münch J,Springael JY,Nijmeijer S,Forssmann WG,Vischer HF,Vakili J,Detheux M,Parmentier M,Leurs R,Smit MJ
Wed Jul 15 00:00:00 EDT 2009
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 EDT 2009
Streptococcus agalactiae CspA is a serine protease that inactivates chemokines.
Journal of bacteriology
Bryan JD,Shelver DW
Sun Mar 01 00:00:00 EST 2009
SpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.
PloS one
Egesten A,Olin AI,Linge HM,Yadav M,Mörgelin M,Karlsson A,Collin M
Mon Jun 15 00:00:00 EDT 2009
CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis.
Blood
Truman LA,Ford CA,Pasikowska M,Pound JD,Wilkinson SJ,Dumitriu IE,Melville L,Melrose LA,Ogden CA,Nibbs R,Graham G,Combadiere C,Gregory CD
Mon Dec 15 00:00:00 EST 2008
CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis.
Blood
Truman LA,Ford CA,Pasikowska M,Pound JD,Wilkinson SJ,Dumitriu IE,Melville L,Melrose LA,Ogden CA,Nibbs R,Graham G,Combadiere C,Gregory CD
Mon Dec 15 00:00:00 EST 2008
Bone marrow-derived dendritic cells generated in the presence of resolvin E1 induce apoptosis of activated CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Vassiliou EK,Kesler OM,Tadros JH,Ganea D
Wed Oct 01 00:00:00 EDT 2008
XCL1 enhances regulatory activities of CD4+ CD25(high) CD127(low/-) T cells in human allergic asthma.
Journal of immunology (Baltimore, Md. : 1950)
Nguyen KD,Fohner A,Booker JD,Dong C,Krensky AM,Nadeau KC
Wed Oct 15 00:00:00 EDT 2008
A critical role for TNFalpha in the selective attachment of mononuclear leukocytes to angiotensin-II-stimulated arterioles.
Blood
Mateo T,Naim Abu Nabah Y,Losada M,Estellés R,Company C,Bedrina B,Cerdá-Nicolás JM,Poole S,Jose PJ,Cortijo J,Morcillo EJ,Sanz MJ
Sat Sep 15 00:00:00 EDT 2007
CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration.
Arteriosclerosis, thrombosis, and vascular biology
Abu Nabah YN,Losada M,Estellés R,Mateo T,Company C,Piqueras L,Lopez-Gines C,Sarau H,Cortijo J,Morcillo EJ,Jose PJ,Sanz MJ
Thu Nov 01 00:00:00 EDT 2007
CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration.
Arteriosclerosis, thrombosis, and vascular biology
Abu Nabah YN,Losada M,Estellés R,Mateo T,Company C,Piqueras L,Lopez-Gines C,Sarau H,Cortijo J,Morcillo EJ,Jose PJ,Sanz MJ
Thu Nov 01 00:00:00 EDT 2007
The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.
Stem cells (Dayton, Ohio)
Ponte AL,Marais E,Gallay N,Langonné A,Delorme B,Hérault O,Charbord P,Domenech J
Sun Jul 01 00:00:00 EDT 2007
CCR5-dependent homing of naturally occurring CD4+ regulatory T cells to sites of Leishmania major infection favors pathogen persistence.
The Journal of experimental medicine
Yurchenko E,Tritt M,Hay V,Shevach EM,Belkaid Y,Piccirillo CA
Mon Oct 30 00:00:00 EST 2006
Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors.
Stem cells (Dayton, Ohio)
Honczarenko M,Le Y,Swierkowski M,Ghiran I,Glodek AM,Silberstein LE
Sat Apr 01 00:00:00 EST 2006
Human herpesvirus 7 open reading frames U12 and U51 encode functional beta-chemokine receptors.
Journal of virology
Tadagaki K,Nakano K,Yamanishi K
Wed Jun 01 00:00:00 EDT 2005
Human tumor antigen MUC1 is chemotactic for immature dendritic cells and elicits maturation but does not promote Th1 type immunity.
Journal of immunology (Baltimore, Md. : 1950)
Carlos CA,Dong HF,Howard OM,Oppenheim JJ,Hanisch FG,Finn OJ
Mon Aug 01 00:00:00 EDT 2005
GRO family chemokines are specialized for monocyte arrest from flow.
American journal of physiology. Heart and circulatory physiology
Smith DF,Galkina E,Ley K,Huo Y
Tue Nov 01 00:00:00 EST 2005
MCP-1 is induced by receptor activator of nuclear factor-{kappa}B ligand, promotes human osteoclast fusion, and rescues granulocyte macrophage colony-stimulating factor suppression of osteoclast formation.
The Journal of biological chemistry
Kim MS,Day CJ,Morrison NA
Fri Apr 22 00:00:00 EDT 2005
Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas.
Blood
Trentin L,Cabrelle A,Facco M,Carollo D,Miorin M,Tosoni A,Pizzo P,Binotto G,Nicolardi L,Zambello R,Adami F,Agostini C,Semenzato G
Thu Jul 15 00:00:00 EDT 2004
Blocking HIV-1 infection via CCR5 and CXCR4 receptors by acting in trans on the CCR2 chemokine receptor.
The EMBO journal
Rodríguez-Frade JM,del Real G,Serrano A,Hernanz-Falcón P,Soriano SF,Vila-Coro AJ,de Ana AM,Lucas P,Prieto I,Martínez-A C,Mellado M
Wed Jan 14 00:00:00 EST 2004
Human P-selectin glycoprotein ligand-1 (PSGL-1) interacts with the skin-associated chemokine CCL27 via sulfated tyrosines at the PSGL-1 amino terminus.
The Journal of biological chemistry
Hirata T,Furukawa Y,Yang BG,Hieshima K,Fukuda M,Kannagi R,Yoshie O,Miyasaka M
Fri Dec 10 00:00:00 EST 2004
CCR5-binding chemokines modulate CXCL12 (SDF-1)-induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor.
Blood
Honczarenko M,Le Y,Glodek AM,Majka M,Campbell JJ,Ratajczak MZ,Silberstein LE
Tue Oct 01 00:00:00 EDT 2002
The CC chemokine RANTES in breast carcinoma progression: regulation of expression and potential mechanisms of promalignant activity.
Cancer research
Azenshtein E,Luboshits G,Shina S,Neumark E,Shahbazian D,Weil M,Wigler N,Keydar I,Ben-Baruch A
Fri Feb 15 00:00:00 EST 2002
Functional expression and characterization of macaque C-C chemokine receptor 3 (CCR3) and generation of potent antagonistic anti-macaque CCR3 monoclonal antibodies.
The Journal of biological chemistry
Zhang L,Soares MP,Guan Y,Matheravidathu S,Wnek R,Johnson KE,Meisher A,Iliff SA,Mudgett JS,Springer MS,Daugherty BL
Fri Sep 13 00:00:00 EDT 2002
Amyloid-beta induces chemotaxis and oxidant stress by acting at formylpeptide receptor 2, a G protein-coupled receptor expressed in phagocytes and brain.
The Journal of biological chemistry
Tiffany HL,Lavigne MC,Cui YH,Wang JM,Leto TL,Gao JL,Murphy PM
Fri Jun 29 00:00:00 EDT 2001
CCR5 provides a signal for microbial induced production of IL-12 by CD8 alpha+ dendritic cells.
Nature immunology
Aliberti J,Reis e Sousa C,Schito M,Hieny S,Wells T,Huffnagle GB,Sher A
Sat Jul 01 00:00:00 EDT 2000
The role of HIV-related chemokine receptors and chemokines in human erythropoiesis in vitro.
Stem cells (Dayton, Ohio)
Majka M,Ratajczak J,Lee B,Honczarenko M,Douglas R,Kowalska MA,Silberstein L,Gewirtz AM,Ratajczak MZ
Mon Jun 26 00:00:00 EDT 2000
CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines.
The Journal of biological chemistry
Schweickart VL,Epp A,Raport CJ,Gray PW
Fri Mar 31 00:00:00 EST 2000
Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma.
Cancer research
Luboshits G,Shina S,Kaplan O,Engelberg S,Nass D,Lifshitz-Mercer B,Chaitchik S,Keydar I,Ben-Baruch A
Wed Sep 15 00:00:00 EDT 1999
CD26/dipeptidyl-peptidase IV down-regulates the eosinophil chemotactic potency, but not the anti-HIV activity of human eotaxin by affecting its interaction with CC chemokine receptor 3.
Journal of immunology (Baltimore, Md. : 1950)
Struyf S,Proost P,Schols D,De Clercq E,Opdenakker G,Lenaerts JP,Detheux M,Parmentier M,De Meester I,Scharpé S,Van Damme J
Thu Apr 15 00:00:00 EDT 1999
Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways.
Journal of immunology (Baltimore, Md. : 1950)
Sabroe I,Hartnell A,Jopling LA,Bel S,Ponath PD,Pease JE,Collins PD,Williams TJ
Mon Mar 01 00:00:00 EST 1999
Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.
The Journal of biological chemistry
Oppermann M,Mack M,Proudfoot AE,Olbrich H
Fri Mar 26 00:00:00 EST 1999
Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3.
The Journal of biological chemistry
Kitaura M,Suzuki N,Imai T,Takagi S,Suzuki R,Nakajima T,Hirai K,Nomiyama H,Yoshie O
Fri Sep 24 00:00:00 EDT 1999
Chemokines and the arrest of lymphocytes rolling under flow conditions.
Science (New York, N.Y.)
Campbell JJ,Hedrick J,Zlotnik A,Siani MA,Thompson DA,Butcher EC
Fri Jan 16 00:00:00 EST 1998
Chemokine sequestration by viral chemoreceptors as a novel viral escape strategy: withdrawal of chemokines from the environment of cytomegalovirus-infected cells.
The Journal of experimental medicine
Bodaghi B,Jones TR,Zipeto D,Vita C,Sun L,Laurent L,Arenzana-Seisdedos F,Virelizier JL,Michelson S
Mon Sep 07 00:00:00 EDT 1998
HIV-1 envelope gp120 inhibits the monocyte response to chemokines through CD4 signal-dependent chemokine receptor down-regulation.
Journal of immunology (Baltimore, Md. : 1950)
Wang JM,Ueda H,Howard OM,Grimm MC,Chertov O,Gong X,Gong W,Resau JH,Broder CC,Evans G,Arthur LO,Ruscetti FW,Oppenheim JJ
Thu Oct 15 00:00:00 EDT 1998
Type I IFNs enhance the terminal differentiation of dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Luft T,Pang KC,Thomas E,Hertzog P,Hart DN,Trapani J,Cebon J
Sat Aug 15 00:00:00 EDT 1998
Identification of single C motif-1/lymphotactin receptor XCR1.
The Journal of biological chemistry
Yoshida T,Imai T,Kakizaki M,Nishimura M,Takagi S,Yoshie O
Fri Jun 26 00:00:00 EDT 1998
Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309.
The Journal of experimental medicine
Tiffany HL,Lautens LL,Gao JL,Pease J,Locati M,Combadiere C,Modi W,Bonner TI,Murphy PM
Mon Jul 07 00:00:00 EDT 1997
Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309.
The Journal of experimental medicine
Tiffany HL,Lautens LL,Gao JL,Pease J,Locati M,Combadiere C,Modi W,Bonner TI,Murphy PM
Mon Jul 07 00:00:00 EDT 1997
Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage.
The Journal of experimental medicine
Oravecz T,Pall M,Roderiquez G,Gorrell MD,Ditto M,Nguyen NY,Boykins R,Unsworth E,Norcross MA
Mon Dec 01 00:00:00 EST 1997