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          • Proteins & Peptides ›
          • CCL8 (MCP2) Proteins
          The PeproTech website has now moved to Thermofisher.com. All orders for PeproTech products must be placed on thermofisher.com or offline via phone, fax, email, or distributor partner. For any questions, please contact PeproTech.CustomerService@thermofisher.com

          Gibco

          Human CCL8 (MCP-2) Recombinant Protein, PeproTech®

          21 References
          View all (4) CCL8 (MCP2) proteins
          Datasheet
          Tech Support
          Datasheet
          Tech Support

          Cite Human CCL8 (MCP-2) Recombinant Protein, PeproTech®

          • Testing Data (1)
          Human CCL8 (MCP-2) Protein in Functional Assay (Functional)
          Group 53 Created with Sketch.
          Human CCL8 (MCP-2) Protein in Functional Assay (Functional)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          Human CCL8 (MCP-2) Protein (300-15-100UG) in Functional

          Bioassay analysis of Human CCL8 (MCP-2) Recombinant Protein, PeproTech® (Product # 300-15-1MG). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Human CCL8 (MCP-2) Protein in Functional Assay (Functional)

          Product Details

          300-15-100UG

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          Assay-dependent
          -

          ELISA (ELISA)

          Assay-dependent
          View 3 publications 3 publications

          Functional Assay (Functional)

          Assay-dependent
          -

          In vitro Assay (IV)

          -
          View 16 publications 16 publications

          Miscellaneous PubMed (Misc)

          -
          View 2 publications 2 publications
          Product Specifications

          Species

          Human

          Published species

          Bacteria, Hamster, Human, Mouse

          Expression System

          E. coli

          Amino acid sequence

          QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP

          Molecular weight

          8.9 kDa

          Class

          Recombinant

          Type

          Protein

          Purity

          ≥ 98% by SDS-PAGE gel and HPLC analyses.

          Endotoxin concentration

          <1 EU/µg

          Activity

          Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng/ml.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Purification

          purified

          Contains

          no preservative

          Storage conditions

          -20°C

          Shipping conditions

          Ambient

          Product Specific Information

          Recombinant Human MCP-2 is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

          This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

          Target Information

          This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: C-C motif chemokine 8; chemokine (C-C motif) ligand 8; HC14; MCP-2; Monocyte chemoattractant protein 2; Monocyte chemotactic protein 2; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); Small-inducible cytokine A8

          View more View less

          Gene Aliases: CCL8; HC14; MCP-2; MCP2; SCYA10; SCYA8

          View more View less

          UniProt ID: (Human) P80075

          View more View less

          Entrez Gene ID: (Human) 6355

          View more View less

          It has to be done as per old AB suggested Products section.
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