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Invitrogen
Human Cathelicidin Synthetic Peptide
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Product Details
GSC00002P
Product Specifications
Class
Synthetic
Type
Peptide
Conjugate
Form
Lyophilized
Amount
50 µg
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
GSC00002P is the immunizing peptide for the rabbit antibody to human CAP-18 (OSC00009W,OSC00028G)
GSC00002P may be used as a control in various immunology applications.
Reconstitute with PBS or distilled water.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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