Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (67%), Rat (67%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-81923. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Factor I, a serine protease, is a regulatory component of both the alternative and the classical complement pathway. Factor I is synthesized as a single chain precursor of 88 kDa, processed to yield the active form, composed of two disulfide-linked chains, the a-chain (50 kDa) and the b-chain (38 kDa). Plasma concentration is 35 µg/mL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C3b-inactivator; C3B/C4B inactivator; complement component I; complement control protein factor I; Complement factor I; complement factor I heavy chain; factor i; Konglutinogen-activating factor; light chain of factor I
Gene Aliases: AHUS3; ARMD13; C3b-INA; C3BINA; CFI; FI; IF; KAF
UniProt ID: (Human) P05156
Entrez Gene ID: (Human) 3426
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