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Invitrogen
Human Cripto-1 His-tag Recombinant Protein
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Product Details
RP-87818
Product Specifications
Expression System
HEK293 cells
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
25 µg
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Carrier-Free
Stock solutions can also be prepared at 50 - 100 µg/mL in appropriate sterile buffer, carrier protein such as 0.2 - 1% BSA or HSA can be added when preparing the stock solution.
Target Information
Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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