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This peptide corresponds to 18 amino acid peptide near the carboxy terminus of human Requiem.
PEP-1193 can be used as a blocking peptide with polyclonal antibody PA5-21079.
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
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Protein Aliases: Apoptosis response zinc finger protein; BAF45D; BRG1-associated factor 45D; D4, zinc and double PHD fingers family 2; Protein requiem; requiem; requiem, apoptosis response zinc finger; Zinc finger protein ubi-d4
Gene Aliases: BAF45D; DPF2; REQ; ubi-d4; UBID4
UniProt ID: (Human) Q92785
Entrez Gene ID: (Human) 5977
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