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Highest antigen sequence indentity to the following orthologs: Mouse (90%), Rat (90%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-110629. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoplasmic reticulum resident protein 44; endoplasmic reticulum resident protein 44 kDa; ER protein 44; OTTHUMP00000063799; protein disulfide isomerase family A, member 10; thioredoxin domain containing 4 (endoplasmic reticulum); Thioredoxin domain-containing protein 4
Gene Aliases: ERP44; KIAA0573; PDIA10; TXNDC4; UNQ532/PRO1075
UniProt ID: (Human) Q9BS26
Entrez Gene ID: (Human) 23071
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