Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 18 amino acid peptide near the amino terminus of human RBM35A.
PEP-1223 can be used as a blocking peptide with polyclonal antibody PA5-21109.
RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.
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Protein Aliases: Epithelial splicing regulatory protein 1; RNA binding motif protein 35A; RNA-binding motif protein 35A; RNA-binding protein 35A
Gene Aliases: ESRP1; RBM35A; RMB35A
UniProt ID: (Human) Q6NXG1
Entrez Gene ID: (Human) 54845
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