Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recombinant Human Epigen is a 7.9 kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF-homologous portion of the Epigen precursor.
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Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. It is produced in several tissues, including the testis, liver, and heart, as well as in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EPG; Epigen; Epithelial mitogen; epithelial mitogen homolog
Gene Aliases: ALGV3072; EPG; EPGN; PRO9904; UNQ3072/PRO9904
UniProt ID: (Human) Q6UW88
Entrez Gene ID: (Human) 255324
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