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Invitrogen
Human FAM9B (aa 121-184) Control Fragment Recombinant Protein
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Product Details
RP-95467
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
EEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSEL
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (44%), Rat (44%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57171. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The FAM9B gene, also known as Family With Sequence Similarity 9 Member B, is located on the X chromosome at Xp22.3. This gene is specifically expressed in the testes and is involved in meiotic processes crucial for gametogenesis. FAM9B encodes a protein that localizes to meiotic chromosome cores, playing a role in the regulation and stabilization of chromosome segregation during meiosis. Its expression pattern suggests a fundamental role in the generation of gametes, and defects in this gene could have implications for male fertility. The detailed mechanisms by which FAM9B functions are still under investigation, but its association with meiosis highlights its importance in reproductive biology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 9, member B; Protein FAM9B; testis expressed 39B
Gene Aliases: FAM9B; TEX39B
UniProt ID: (Human) Q8IZU0
Entrez Gene ID: (Human) 171483
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