Product References
Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization.
Cellular oncology (Dordrecht, Netherlands)
McAloney CA,Makkawi R,Budhathoki Y,Cannon MV,Franz EM,Gross AC,Cam M,Vetter TA,Duhen R,Davies AE,Roberts RD
100-28 was used in In vitro experiments to develop therapeutic strategies that prevent and treat metastasis by identifying mechanisms that facilitate survival of disseminated tumour cells.
Thu Feb 01 00:00:00 EST 2024
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B.
The EMBO journal
Cinque L,De Leonibus C,Iavazzo M,Krahmer N,Intartaglia D,Salierno FG,De Cegli R,Di Malta C,Svelto M,Lanzara C,Maddaluno M,Wanderlingh LG,Huebner AK,Cesana M,Bonn F,Polishchuk E,Hübner CA,Conte I,Dikic I,Mann M,Ballabio A,Sacco F,Grumati P,Settembre C
Tue Sep 01 00:00:00 EDT 2020
FGF18-FGFR2 signaling triggers the activation of c-Jun-YAP1 axis to promote carcinogenesis in a subgroup of gastric cancer patients and indicates translational potential.
Oncogene
Zhang J,Wong CC,Leung KT,Wu F,Zhou Y,Tong JHM,Chan RCK,Li H,Wang Y,Yan H,Liu L,Wu WKK,Chan MWY,Cheng ASL,Yu J,Wong N,Lo KW,To KF,Kang W
Thu Oct 01 00:00:00 EDT 2020
Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes.
Scientific reports
Westphal S,Gantert T,Kless C,Hüttinger K,Klingenspor M,Fromme T
Tue Jun 11 00:00:00 EDT 2019
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes.
Scientific reports
Savchenko E,Teku GN,Boza-Serrano A,Russ K,Berns M,Deierborg T,Lamas NJ,Wichterle H,Rothstein J,Henderson CE,Vihinen M,Roybon L
Wed Jul 03 00:00:00 EDT 2019
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes.
Scientific reports
Savchenko E,Teku GN,Boza-Serrano A,Russ K,Berns M,Deierborg T,Lamas NJ,Wichterle H,Rothstein J,Henderson CE,Vihinen M,Roybon L
Wed Jul 03 00:00:00 EDT 2019
Striking a new path in reducing cartilage breakdown: combination of antioxidative therapy and chondroanabolic stimulation after blunt cartilage trauma.
Journal of cellular and molecular medicine
Riegger J,Joos H,Palm HG,Friemert B,Reichel H,Ignatius A,Brenner RE
Mon Jan 01 00:00:00 EST 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor.
eLife
Shuhaibar LC,Robinson JW,Vigone G,Shuhaibar NP,Egbert JR,Baena V,Uliasz TF,Kaback D,Yee SP,Feil R,Fisher MC,Dealy CN,Potter LR,Jaffe LA
Mon Dec 04 00:00:00 EST 2017
Hedgehog inhibits β-catenin activity in synovial joint development and osteoarthritis.
The Journal of clinical investigation
Rockel JS,Yu C,Whetstone H,Craft AM,Reilly K,Ma H,Tsushima H,Puviindran V,Al-Jazrawe M,Keller GM,Alman BA
Mon May 02 00:00:00 EDT 2016
Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis.
Arthritis & rheumatology (Hoboken, N.J.)
Shu CC,Jackson MT,Smith MM,Smith SM,Penm S,Lord MS,Whitelock JM,Little CB,Melrose J
Fri Apr 01 00:00:00 EDT 2016
A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia.
Science signaling
Xiao Z,Riccardi D,Velazquez HA,Chin AL,Yates CR,Carrick JD,Smith JC,Baudry J,Quarles LD
Tue Nov 22 00:00:00 EST 2016
Use of FGF-2 and FGF-18 to direct bone marrow stromal stem cells to chondrogenic and osteogenic lineages.
Future science OA
Shu C,Smith SM,Little CB,Melrose J
Thu Dec 01 00:00:00 EST 2016
A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development.
PLoS genetics
Xu J,Liu H,Lan Y,Aronow BJ,Kalinichenko VV,Jiang R
Fri Jan 01 00:00:00 EST 2016
Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells.
Molecular carcinogenesis
Koneczny I,Schulenburg A,Hudec X,Knöfler M,Holzmann K,Piazza G,Reynolds R,Valent P,Marian B
Tue Sep 01 00:00:00 EDT 2015
FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.
PLoS genetics
Zhou S,Xie Y,Tang J,Huang J,Huang Q,Xu W,Wang Z,Luo F,Wang Q,Chen H,Du X,Shen Y,Chen D,Chen L
Mon Jun 01 00:00:00 EDT 2015
Possible association of IL-4 VNTR polymorphism with susceptibility to preeclampsia.
BioMed research international
Salimi S,Mohammadoo-Khorasani M,Yaghmaei M,Mokhtari M,Moossavi M
Thu Feb 12 00:00:00 EST 2015
Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling.
Nature
Yang W,Wang J,Moore DC,Liang H,Dooner M,Wu Q,Terek R,Chen Q,Ehrlich MG,Quesenberry PJ,Neel BG
Thu Jul 25 00:00:00 EDT 2013
Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix.
Proceedings of the National Academy of Sciences of the United States of America
Martino MM,Briquez PS,Ranga A,Lutolf MP,Hubbell JA
Tue Mar 19 00:00:00 EDT 2013
Fibroblast growth factor 2 drives changes in gene expression following injury to murine cartilage in vitro and in vivo.
Arthritis and rheumatism
Chong KW,Chanalaris A,Burleigh A,Jin H,Watt FE,Saklatvala J,Vincent TL
Sun Sep 01 00:00:00 EDT 2013
Bent bone dysplasia-FGFR2 type, a distinct skeletal disorder, has deficient canonical FGF signaling.
American journal of human genetics
Merrill AE,Sarukhanov A,Krejci P,Idoni B,Camacho N,Estrada KD,Lyons KM,Deixler H,Robinson H,Chitayat D,Curry CJ,Lachman RS,Wilcox WR,Krakow D
Fri Mar 09 00:00:00 EST 2012
Fibroblast growth factor receptor 3 effects on proliferation and telomerase activity in sheep growth plate chondrocytes.
Journal of animal science and biotechnology
Smith LB,Belanger JM,Oberbauer AM
Fri Dec 07 00:00:00 EST 2012
Species-specific biological effects of FGF-2 in articular cartilage: implication for distinct roles within the FGF receptor family.
Journal of cellular biochemistry
Li X,Ellman MB,Kroin JS,Chen D,Yan D,Mikecz K,Ranjan KC,Xiao G,Stein GS,Kim SG,Cole B,van Wijnen AJ,Im HJ
Sun Jul 01 00:00:00 EDT 2012
Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes.
Arthritis research & therapy
Yan D,Chen D,Cool SM,van Wijnen AJ,Mikecz K,Murphy G,Im HJ
Thu Aug 11 00:00:00 EDT 2011
Action of fibroblast growth factor-2 on the intervertebral disc.
Arthritis research & therapy
Li X,An HS,Ellman M,Phillips F,Thonar EJ,Park DK,Udayakumar RK,Im HJ
Tue Sep 23 00:00:00 EDT 2008
Human immortalized chondrocytes carrying heterozygous FGFR3 mutations: an in vitro model to study chondrodysplasias.
FEBS letters
Benoist-Lasselin C,Gibbs L,Heuertz S,Odent T,Munnich A,Legeai-Mallet L
Tue Jun 12 00:00:00 EDT 2007
FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate.
Developmental biology
Liu Z,Lavine KJ,Hung IH,Ornitz DM
Thu Feb 01 00:00:00 EST 2007
Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.
The Journal of biological chemistry
Zhang X,Ibrahimi OA,Olsen SK,Umemori H,Mohammadi M,Ornitz DM
Fri Jun 09 00:00:00 EDT 2006
FGF-18 is upregulated in the postnatal rat lung and enhances elastogenesis in myofibroblasts.
American journal of physiology. Lung cellular and molecular physiology
Chailley-Heu B,Boucherat O,Barlier-Mur AM,Bourbon JR
Sat Jan 01 00:00:00 EST 2005
Fibroblast growth factor (FGF) 18 signals through FGF receptor 3 to promote chondrogenesis.
The Journal of biological chemistry
Davidson D,Blanc A,Filion D,Wang H,Plut P,Pfeffer G,Buschmann MD,Henderson JE
Fri May 27 00:00:00 EDT 2005
FGF18 represses noggin expression and is induced by calcineurin.
The Journal of biological chemistry
Reinhold MI,Abe M,Kapadia RM,Liao Z,Naski MC
Fri Sep 10 00:00:00 EDT 2004
BMP4 modulates fibroblast growth factor-mediated induction of proximal and distal lung differentiation in mouse embryonic tracheal epithelium in mesenchyme-free culture.
Developmental dynamics : an official publication of the American Association of Anatomists
Hyatt BA,Shangguan X,Shannon JM
Tue Oct 01 00:00:00 EDT 2002