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Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
c-FOS is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. It has a critical function in regulating the development of cells destined to form and maintain the skeleton, and is thought to have an important role in signal transduction, cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: activator protein 1; DKFZp686C0818; FBJ murine osteosarcoma viral oncogene homolog B; fos b; FOSB; FosB proto-oncogene, AP-1 trancription factor subunit; FosB proto-oncogene, AP-1 transcription factor subunit; G0/G1 switch regulatory protein 3; GOS3 is human homolog of mouse FOSB gene; MGC42291; oncogene FOS-B; Protein FosB; Transcription factor AP-1 subunit FosB; unnamed protein product
Gene Aliases: AP-1; FOSB; G0S3; GOS3; GOSB
UniProt ID: (Human) P53539
Entrez Gene ID: (Human) 2354
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