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Invitrogen
Human GALR1 (aa 1-36) Control Fragment Recombinant Protein
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Product Details
RP-109415
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVT
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gal receptor 1; Gal-1 receptor; Gal-r1; GAL1-R; Galanin r1 receptor; Galanin receptor type 1; Galanin-1 receptor; Galn1r; GALR-1; Hugal 1-r
Gene Aliases: GALNR; GALNR1; GALR1
UniProt ID: (Human) P47211
Entrez Gene ID: (Human) 2587
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