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Invitrogen
Human GBP5 Synthetic Peptide
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Product Details
PEP-1584
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
50 µg
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human GBP5.
PEP-1584 can be used as a blocking peptide with polyclonal antibody PA5-34541. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37°C.
Target Information
The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GBP-5; GBP-TA antigen; GBP5; GTP-binding protein 5; Guanine nucleotide-binding protein 5; Guanylate-binding protein 5; tumor-specific antigen of cutaneous T-cell lymphoma; unnamed protein product
Gene Aliases: GBP-5; GBP5; UNQ2427/PRO4987
UniProt ID: (Human) Q96PP8
Entrez Gene ID: (Human) 115362
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