Gibco

Human GDF-7 Recombinant Protein, PeproTech®

Human GDF-7 Protein in Functional Assay (FN)

FIGURE: 1 / 1

Human GDF-7 Protein (120-37-100UG) in FN

Bioassay analysis of Human GDF-7 Recombinant Protein, PeproTech® (Product # 120-37-1MG).

Product Image Gallery

Product Details

120-37-100UG

Applications

Tested Dilution

Publications

Functional Assay (FN)

Assay-dependent

In vitro Assay (IV)

View 4 publications 4 publications

Product Specifications

Species

Human

Published species

Human, Rat

Expression System

E. coli

Amino acid sequence

TALAGTRTAQ GSGGGAGRGH GRRGRSRCSR KPLHVDFKEL GWDDWIIAPL DYEAYHCEGL CDFPLRSHLE PTNHAIIQTL LNSMAPDAAP ASCCVPARLS PISILYIDAA NNVVYKQYED MVVEACGCR

Molecular weight

28 kDa

Class

Recombinant

Type

Protein

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin concentration

<1 EU/µg

Activity

Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient

Product Specific Information

Recombinant Human GDF-7 is a 28.0 kDa disulfide-linked homodimer containing two 129 amino acid residues.

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Target Information

This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Long Z,Nakagawa K,Wang Z,Amadio PC,Zhao C,Gingery A

120-37 was used in Cell Culture to explore the cellular differences found between young, mature, and aged rotator cuff enthesis cells and highlights the importance of using age-appropriate models, as well as provides a basis for further delineation of mechanisms and potential therapeutics for rotator cuff injuries.

Mon Aug 01 00:00:00 EDT 2022

CREB signaling activity correlates with differentiation and survival in medulloblastoma.

Scientific reports

Armandari I,Zomerman WW,Plasschaert SLA,Smit MJ,Martini TEI,de Camargo Magalhães ES,Hogeling SM,Rozema-Huizinga GC,Lourens HJ,Meeuwsen-de Boer TGJ,Scherpen FJG,de Bont ESJM,Bruggeman SWM

Mon Aug 09 00:00:00 EDT 2021

Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway.

Journal of cellular physiology

Wang Y,He G,Tang H,Shi Y,Zhu M,Kang X,Bian X,Lyu J,Zhou M,Yang M,Mu M,Chen W,Zhou B,Yuan C,Zhang J,Tang K

120-37 was used in In vitro experiments to find that aspirin promoted tenogenesis of TSCs.

Fri May 01 00:00:00 EDT 2020

The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells.