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Product Details
PEP-0254
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Dry ice
Product Specific Information
This peptide corresponds to 15 amino acids near the center of human GFR-Alpha-2.
PEP-0254 can be used as a blocking peptide with polyclonal antibody PA5-19874.
Target Information
GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDNF family receptor alpha-2; GDNF re; GDNF receptor alpha-2; GDNF receptor beta; GDNFR-alpha-2; GDNFR-beta; GFR-alpha 2; GFR-alpha-2; glial cell line derived neurotrophic factor receptor, beta; HpV18gp1; Neurturin receptor alpha; NRTNR-alpha; NTNR-alpha; PI-linked cell-surface accessory protein; RET ligand 2; TGF-beta-related neurotrophic factor receptor 2; TRN receptor, GPI-anchored
Gene Aliases: GDNFRB; GFRA2; NRTNR-ALPHA; NTNRA; RETL2; TRNR2
UniProt ID: (Human) O00451
Entrez Gene ID: (Human) 2675
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