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Highest antigen sequence indentity to the following orthologs: Mouse (68%), Rat (68%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55529. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Autoantigen NGP-1; guanine nucleotide binding protein-like 2 (nucleolar); novel nucleolar guanosine 5'-triphosphate binding protein autoantigen; nucleolar G-protein gene 1; Nucleolar GTP-binding protein 2; nucleolar GTPase; nucleostemin-2
Gene Aliases: GNL2; HUMAUANTIG; Ngp-1; NGP1; Nog2; Nug2
UniProt ID: (Human) Q13823
Entrez Gene ID: (Human) 29889
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