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Gibco
Human GRO-gamma (CXCL3) Recombinant Protein, PeproTech®
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Product Details
300-40-10UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Published species
Bacteria,
Hamster,
Human,
Mouse,
Protozoa
Expression System
E. coli
Amino acid sequence
ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN
Molecular weight
7.9 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/ml.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Human GRO-gamma is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
CXCL3 may play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 3; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 3; CXC; CXC motif chemokine; CXCL; gro gamma; GRO-gamma; GRO-gamma(1-73); GRO3 oncogene; Growth-regulated protein gamma; Macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; MGSA gamma; MIP2-beta
Gene Aliases: CINC-2b; CXCL3; GRO3; GROG; MIP-2b; MIP2B; SCYB3
UniProt ID: (Human) P19876
Entrez Gene ID: (Human) 2921
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