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Invitrogen
Human GZF1 Synthetic Peptide
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Product Details
PEP-1418
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Amount
50 µg
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
This peptide corresponds to 18 amino acid peptide near the carboxy terminus of human GZF1.
PEP-1418 can be used as a blocking peptide with polyclonal antibody PA5-34375.
Target Information
The GDNF-inducible zinc finger protein 1 (GZF1) is a sequence-specific transcriptional repressor with a BTB/POZ domain and ten zinc finger motifs whose expression is required for renal branching morphogenesis during kidney development. GZF1 binds to the 5'regulatory region of the homeodomain protein HOXA10, suggesting that GZF1 may play a role in morphogenesis other than kidney development. Recent experiments have indicated that GZF1 associates with nucleolin and this association is mediated by the first four zinc finger motifs of GZF1. It is thought that Nucleolin modulates the subcellular localization of GZF1 as well as its transcriptional repressor activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDNF-inducible zinc finger protein 1; unnamed protein product; Zinc finger and BTB domain-containing protein 23; Zinc finger protein 336
Gene Aliases: GZF1; JLSM; ZBTB23; ZNF336
UniProt ID: (Human) Q9H116
Entrez Gene ID: (Human) 64412
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