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This peptide corresponds to 15 amino acids near the amino terminus of human T-cadherin.
PEP-0277 can be used as a blocking peptide with polyclonal antibody PA5-20158.
The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: CAD13; cadherin 13, H-cadherin (heart); Cadherin-13; CD39-like 3; CD39L3; ecto-apyrase 3; ecto-ATPase 3; ecto-ATPDase 3; H-cadherin; H-cadherin (heart); Heart cadherin; heart-cadherin; NTPDase-3; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated cadherin; truncated-cadherin
Gene Aliases: CDH13; CDHH; P105
UniProt ID: (Human) P55290
Entrez Gene ID: (Human) 1012
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