Product References
Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling.
PLoS pathogens
Ohnezeit D,Huang J,Westerkamp U,Brinschwitz V,Schmidt C,Günther T,Czech-Sioli M,Weißelberg S,Schlemeyer T,Nakel J,Mai J,Schreiner S,Schneider C,Friedel CC,Schwanke H,Brinkmann MM,Grundhoff A,Fischer N
300-02BC was used in Cell Culture to identify novel functions of early viral proteins by performing genome-wide transcriptome and chromatin studies in primary human fibroblasts.
Thu Aug 01 00:00:00 EDT 2024
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Nature communications
Linnerbauer M,Beyer T,Nirschl L,Farrenkopf D,Lößlein L,Vandrey O,Peter A,Tsaktanis T,Kebir H,Laplaud D,Oellinger R,Engleitner T,Alvarez JI,Rad R,Korn T,Hemmer B,Quintana FJ,Rothhammer V
300-02BC was used in Cell Culture to suggest the glial PD-L1/PD-1 axis as a potential therapeutic target for both acute and progressive MS stages.
Sat Sep 09 00:00:00 EDT 2023
IFN-γ Induces IL-15 Trans-Presentation by Epithelial Cells via IRF1.
Journal of immunology (Baltimore, Md. : 1950)
Kim TS,Rha MS,Shin EC
Sat Jan 15 00:00:00 EST 2022
JAK inhibitor blocks COVID-19 cytokine-induced JAK/STAT/APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids.
JCI insight
Nystrom SE,Li G,Datta S,Soldano KL,Silas D,Weins A,Hall G,Thomas DB,Olabisi OA
300-02BC was used in Cell Culture to investigate mechanisms of COVID-19 associated nephropathy.
Wed Jun 08 00:00:00 EDT 2022
Optogenetic-controlled immunotherapeutic designer cells for post-surgical cancer immunotherapy.
Nature communications
Yu Y,Wu X,Wang M,Liu W,Zhang L,Zhang Y,Hu Z,Zhou X,Jiang W,Zou Q,Cai F,Ye H
300-02BC was used in In vivo experiments to show that FLICs-loaded hydrogel implants placed at the surgical wound site achieve sustainable release of immunomodulatory cytokines, leading to prevention of tumor recurrence and increased animal survival.
Wed Oct 26 00:00:00 EDT 2022
Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas.
Immunity
Dersh D,Phelan JD,Gumina ME,Wang B,Arbuckle JH,Holly J,Kishton RJ,Markowitz TE,Seedhom MO,Fridlyand N,Wright GW,Huang DW,Ceribelli M,Thomas CJ,Lack JB,Restifo NP,Kristie TM,Staudt LM,Yewdell JW
Tue Jan 12 00:00:00 EST 2021
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
Signal transduction and targeted therapy
Zhang J,Huang F,Xia B,Yuan Y,Yu F,Wang G,Chen Q,Wang Q,Li Y,Li R,Song Z,Pan T,Chen J,Lu G,Zhang H
Wed May 12 00:00:00 EDT 2021
Differential immune responses in pregnant patients recovered from COVID-19.
Signal transduction and targeted therapy
Chen G,Zhang Y,Zhang Y,Ai J,Yang B,Cui M,Liao Q,Chen H,Bai H,Shang D,Chen J,Sun C,Liu H,Liu F,Mao B,Sun G,Chen L,Lin JW,Li K
Thu Jul 29 00:00:00 EDT 2021
Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response.
Cell host & microbe
Lin JW,Tang C,Wei HC,Du B,Chen C,Wang M,Zhou Y,Yu MX,Cheng L,Kuivanen S,Ogando NS,Levanov L,Zhao Y,Li CL,Zhou R,Li Z,Zhang Y,Sun K,Wang C,Chen L,Xiao X,Zheng X,Chen SS,Zhou Z,Yang R,Zhang D,Xu M,Song J,Wang D,Li Y,Lei S,Zeng W,Yang Q,He P,Zhang Y,Zhou L,Cao L,Luo F,Liu H,Wang L,Ye F,Zhang M,Li M,Fan W,Li X,Li K,Ke B,Xu J,Yang H,He S,Pan M,Yan Y,Zha Y,Jiang L,Yu C,Liu Y,Xu Z,Li Q,Jiang Y,Sun J,Hong W,Wei H,Lu G,Vapalahti O,Luo Y,Wei Y,Connor T,Tan W,Snijder EJ,Smura T,Li W,Geng J,Ying B,Chen L
Wed Mar 10 00:00:00 EST 2021
Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response.
Cell host & microbe
Lin JW,Tang C,Wei HC,Du B,Chen C,Wang M,Zhou Y,Yu MX,Cheng L,Kuivanen S,Ogando NS,Levanov L,Zhao Y,Li CL,Zhou R,Li Z,Zhang Y,Sun K,Wang C,Chen L,Xiao X,Zheng X,Chen SS,Zhou Z,Yang R,Zhang D,Xu M,Song J,Wang D,Li Y,Lei S,Zeng W,Yang Q,He P,Zhang Y,Zhou L,Cao L,Luo F,Liu H,Wang L,Ye F,Zhang M,Li M,Fan W,Li X,Li K,Ke B,Xu J,Yang H,He S,Pan M,Yan Y,Zha Y,Jiang L,Yu C,Liu Y,Xu Z,Li Q,Jiang Y,Sun J,Hong W,Wei H,Lu G,Vapalahti O,Luo Y,Wei Y,Connor T,Tan W,Snijder EJ,Smura T,Li W,Geng J,Ying B,Chen L
Wed Mar 10 00:00:00 EST 2021
Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly.
Cell stem cell
Krenn V,Bosone C,Burkard TR,Spanier J,Kalinke U,Calistri A,Salata C,Rilo Christoff R,Pestana Garcez P,Mirazimi A,Knoblich JA
Thu Aug 05 00:00:00 EDT 2021
Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro.
Science translational medicine
Reyes M,Filbin MR,Bhattacharyya RP,Sonny A,Mehta A,Billman K,Kays KR,Pinilla-Vera M,Benson ME,Cosimi LA,Hung DT,Levy BD,Villani AC,Sade-Feldman M,Baron RM,Goldberg MB,Blainey PC,Hacohen N
Wed Jun 16 00:00:00 EDT 2021
Germline SAMD9L truncation variants trigger global translational repression.
The Journal of experimental medicine
Allenspach EJ,Soveg F,Finn LS,So L,Gorman JA,Rosen ABI,Skoda-Smith S,Wheeler MM,Barrow KA,Rich LM,Debley JS,Bamshad MJ,Nickerson DA,Savan R,Torgerson TR,Rawlings DJ
Mon May 03 00:00:00 EDT 2021
Combination of tumor necrosis factor-α and epidermal growth factor induces the adrenergic-to-mesenchymal transdifferentiation in SH-SY5Y neuroblastoma cells.
Cancer science
Huang Y,Tsubota S,Nishio N,Takahashi Y,Kadomatsu K
300-02BC was used in Cell Culture to propose a mechanism of neuroblastoma transdifferentiation induced by extracellular growth factors, which can be controlled in clinical situations, providing a new therapeutic possibility.
Mon Feb 01 00:00:00 EST 2021
Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo.
Molecular therapy oncolytics
Mukesh RK,Kalam AA,Nag J,Jaikumar VS,Kunnakkadan U,Kumar NA,Suma SM,Rajavelu A,Johnson JB
Fri Dec 17 00:00:00 EST 2021
PRL-3 induces a positive signaling circuit between glycolysis and activation of STAT1/2.
The FEBS journal
Vandsemb EN,Rye MB,Steiro IJ,Elsaadi S,Rø TB,Slørdahl TS,Sponaas AM,Børset M,Abdollahi P
Wed Dec 01 00:00:00 EST 2021
Scaffold compound L971 exhibits anti-inflammatory activities through inhibition of JAK/STAT and NFκB signalling pathways.
Journal of cellular and molecular medicine
Li M,Yan Y,Zhang X,Zhang Y,Xu X,Zhang L,Lu L,Wang J,Zhang Y,Song Q,Zhao C
Thu May 20 00:00:00 EDT 2021
The Effect of Interferons on Presentation of Defective Ribosomal Products as HLA Peptides.
Molecular & cellular proteomics : MCP
Komov L,Melamed Kadosh D,Barnea E,Admon A
Mon Mar 21 00:00:00 EDT 2022
Mitochondrial Damage-Induced Innate Immune Activation in Vascular Smooth Muscle Cells Promotes Chronic Kidney Disease-Associated Plaque Vulnerability.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Bi X,Du C,Wang X,Wang XY,Han W,Wang Y,Qiao Y,Zhu Y,Ran L,Liu Y,Xiong J,Huang Y,Liu M,Liu C,Zeng C,Wang J,Yang K,Zhao J
Mon Mar 01 00:00:00 EST 2021
Enterovirus 71 Antagonizes Antiviral Effects of Type III Interferon and Evades the Clearance of Intestinal Intraepithelial Lymphocytes.
Frontiers in microbiology
Dong Y,Liu J,Lu N,Zhang C
300-02BC was used in In vitro experiments to provide novel evasion mechanisms of EV71 from intestinal mucosal innate immunity and may give new insights into antiviral therapy.
Wed Feb 23 00:00:00 EST 2022
Robust COX-2-mediated prostaglandin response may drive arthralgia and bone destruction in patients with chronic inflammation post-chikungunya.
PLoS neglected tropical diseases
Bedoui Y,Septembre-Malaterre A,Giry C,Jaffar-Bandjee MC,Selambarom J,Guiraud P,Gasque P
300-02BC was used in Cell Culture to report novel histological and in vitro data arguing for a plausible role of a COX-2-mediated inflammatory response post-chikungunya virus (CHIKV).
Mon Feb 01 00:00:00 EST 2021
ETV7 regulates breast cancer stem-like cell features by repressing IFN-response genes.
Cell death & disease
Pezzè L,Meškytė EM,Forcato M,Pontalti S,Badowska KA,Rizzotto D,Skvortsova II,Bicciato S,Ciribilli Y
Tue Jul 27 00:00:00 EDT 2021
An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways.
Nature communications
Pardy RD,Valbon SF,Cordeiro B,Krawczyk CM,Richer MJ
Wed Jun 30 00:00:00 EDT 2021
Generation of a chemical genetic model for JAK3.
Scientific reports
Remenyi J,Naik RJ,Wang J,Razsolkov M,Verano A,Cai Q,Tan L,Toth R,Raggett S,Baillie C,Traynor R,Hastie CJ,Gray NS,Arthur JSC
Wed May 12 00:00:00 EDT 2021
A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling.
Nature communications
Banerjee D,Langberg K,Abbas S,Odermatt E,Yerramothu P,Volaric M,Reidenbach MA,Krentz KJ,Rubinstein CD,Brautigan DL,Abbas T,Gelfand BD,Ambati J,Kerur N
Wed Oct 27 00:00:00 EDT 2021
A non-canonical, interferon-independent signaling activity of cGAMP triggers DNA damage response signaling.
Nature communications
Banerjee D,Langberg K,Abbas S,Odermatt E,Yerramothu P,Volaric M,Reidenbach MA,Krentz KJ,Rubinstein CD,Brautigan DL,Abbas T,Gelfand BD,Ambati J,Kerur N
Wed Oct 27 00:00:00 EDT 2021
JAK inhibitors dampen activation of interferon-stimulated transcription of ACE2 isoforms in human airway epithelial cells.
Communications biology
Lee HK,Jung O,Hennighausen L
Wed Jun 02 00:00:00 EDT 2021
JAK inhibitors dampen activation of interferon-activated transcriptomes and the SARS-CoV-2 receptor ACE2 in human renal proximal tubules.
iScience
Jankowski J,Lee HK,Wilflingseder J,Hennighausen L
Fri Aug 20 00:00:00 EDT 2021
Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19.
Cell research
Liu Y,Lv J,Liu J,Li M,Xie J,Lv Q,Deng W,Zhou N,Zhou Y,Song J,Wang P,Qin C,Tong WM,Huang B
Tue Dec 01 00:00:00 EST 2020
Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection.
Immunity
Xiao J,Li W,Zheng X,Qi L,Wang H,Zhang C,Wan X,Zheng Y,Zhong R,Zhou X,Lu Y,Li Z,Qiu Y,Liu C,Zhang F,Zhang Y,Xu X,Yang Z,Chen H,Zhai Q,Wei B,Wang H
Tue Jan 14 00:00:00 EST 2020
Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins.
Nature immunology
Zhou QD,Chi X,Lee MS,Hsieh WY,Mkrtchyan JJ,Feng AC,He C,York AG,Bui VL,Kronenberger EB,Ferrari A,Xiao X,Daly AE,Tarling EJ,Damoiseaux R,Scumpia PO,Smale ST,Williams KJ,Tontonoz P,Bensinger SJ
300-02BC was used in Cell Culture to investigate how pathogens escape cholesterol-dependent cytolysins during infection.
Wed Jul 01 00:00:00 EDT 2020
Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response.
Cell stem cell
Purkayastha A,Sen C,Garcia G,Langerman J,Shia DW,Meneses LK,Vijayaraj P,Durra A,Koloff CR,Freund DR,Chi J,Rickabaugh TM,Mulay A,Konda B,Sim MS,Stripp BR,Plath K,Arumugaswami V,Gomperts BN
300-02BC was used in Cell Culture to show that acute cigarette smoke exposure allows for more severe airway epithelial disease from SARS-CoV-2 by reducing the innate immune response and airway basal stem cells proliferation.
Thu Dec 03 00:00:00 EST 2020
Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.
Cell stem cell
Katsura H,Sontake V,Tata A,Kobayashi Y,Edwards CE,Heaton BE,Konkimalla A,Asakura T,Mikami Y,Fritch EJ,Lee PJ,Heaton NS,Boucher RC,Randell SH,Baric RS,Tata PR
300-02BC was used in Cell Culture to report a feeder-free, scalable, chemically defined, and modular alveolosphere culture system for the propagation and differentiation of human alveolar type 2 cells/pneumocytes derived from primary lung tissue.
Thu Dec 03 00:00:00 EST 2020
SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response.
Cell stem cell
Huang J,Hume AJ,Abo KM,Werder RB,Villacorta-Martin C,Alysandratos KD,Beermann ML,Simone-Roach C,Lindstrom-Vautrin J,Olejnik J,Suder EL,Bullitt E,Hinds A,Sharma A,Bosmann M,Wang R,Hawkins F,Burks EJ,Saeed M,Wilson AA,Mühlberger E,Kotton DN
300-02BC was used in Cell Culture to reveal a model system with cell-intrinsic responses of a key lung target cell to SARS-CoV-2 infection which should facilitate drug development.
Thu Dec 03 00:00:00 EST 2020
Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation.
The Journal of experimental medicine
Zhan X,Guo S,Li Y,Ran H,Huang H,Mi L,Wu J,Wang X,Xiao D,Chen L,Li D,Zhang S,Yan X,Yu Y,Li T,Han Q,He K,Cui J,Li T,Zhou T,Rich JN,Bao S,Zhang X,Li A,Man J
Mon May 04 00:00:00 EDT 2020
Disrupting HIV-1 capsid formation causes cGAS sensing of viral DNA.
The EMBO journal
Sumner RP,Harrison L,Touizer E,Peacock TP,Spencer M,Zuliani-Alvarez L,Towers GJ
Thu Oct 15 00:00:00 EDT 2020
Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage.
The Journal of cell biology
Raso MC,Djoric N,Walser F,Hess S,Schmid FM,Burger S,Knobeloch KP,Penengo L
Mon Aug 03 00:00:00 EDT 2020
Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage.
The Journal of cell biology
Raso MC,Djoric N,Walser F,Hess S,Schmid FM,Burger S,Knobeloch KP,Penengo L
Mon Aug 03 00:00:00 EDT 2020
Annexin A3 in sepsis: novel perspectives from an exploration of public transcriptome data.
Immunology
Toufiq M,Roelands J,Alfaki M,Syed Ahamed Kabeer B,Saadaoui M,Lakshmanan AP,Bangarusamy DK,Murugesan S,Bedognetti D,Hendrickx W,Al Khodor S,Terranegra A,Rinchai D,Chaussabel D,Garand M
Tue Dec 01 00:00:00 EST 2020
Porcine Reproductive and Respiratory Syndrome Virus Enhances Self-Replication via AP-1-Dependent Induction of SOCS1.
Journal of immunology (Baltimore, Md. : 1950)
Luo X,Chen XX,Qiao S,Li R,Xie S,Zhou X,Deng R,Zhou EM,Zhang G
Wed Jan 15 00:00:00 EST 2020
ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity.
Nature communications
Alcalá S,Sancho P,Martinelli P,Navarro D,Pedrero C,Martín-Hijano L,Valle S,Earl J,Rodríguez-Serrano M,Ruiz-Cañas L,Rojas K,Carrato A,García-Bermejo L,Fernández-Moreno MÁ,Hermann PC,Sainz B
Fri May 29 00:00:00 EDT 2020
Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage.
The Journal of biological chemistry
Jobin PG,Solis N,Machado Y,Bell PA,Rai SK,Kwon NH,Kim S,Overall CM,Butler GS
Fri Feb 21 00:00:00 EST 2020
Inhibition of mitochondrial oxidative metabolism attenuates EMCV replication and protects β-cells from virally mediated lysis.
The Journal of biological chemistry
Stafford JD,Shaheen ZR,Yeo CT,Corbett JA
Fri Dec 04 00:00:00 EST 2020
Sequential Interferon β-Cisplatin Treatment Enhances the Surface Exposure of Calreticulin in Cancer Cells via an Interferon Regulatory Factor 1-Dependent Manner.
Biomolecules
Yang PM,Hsieh YY,Du JL,Yen SC,Hung CF
300-02BC was used in Cell Culture to suggest that exogenous IFNβ may activate molecular determinants that convert cisplatin into an ICD inducer.
Tue Apr 21 00:00:00 EDT 2020
Sequential Interferon β-Cisplatin Treatment Enhances the Surface Exposure of Calreticulin in Cancer Cells via an Interferon Regulatory Factor 1-Dependent Manner.
Biomolecules
Yang PM,Hsieh YY,Du JL,Yen SC,Hung CF
300-02BC was used in Cell Culture to suggest that exogenous IFNβ may activate molecular determinants that convert cisplatin into an ICD inducer.
Tue Apr 21 00:00:00 EDT 2020
Respiratory infections regulated blood cells IFN-β-PD-L1 pathway in pediatric asthma.
Immunity, inflammation and disease
Kölle J,Haag P,Vuorinen T,Alexander K,Rauh M,Zimmermann T,Papadopoulos NG,Finotto S
Tue Sep 01 00:00:00 EDT 2020
The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription.
Microorganisms
Fabits M,Gonçalves Magalhães V,Chan B,Girault V,Elbasani E,Rossetti E,Saeland E,Messerle M,Pichlmair A,Lisnić VJ,Brinkmann MM
300-02BC was used in In vivo experiments to identify UL35 as the first HCMV protein to antagonize the type I IFN response at the level of TBK1, thereby enriching our understanding of how this important herpesvirus escapes host immune responses.
Tue May 26 00:00:00 EDT 2020
A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral Compounds.
Frontiers in immunology
Schöler L,Le-Trilling VTK,Eilbrecht M,Mennerich D,Anastasiou OE,Krawczyk A,Herrmann A,Dittmer U,Trilling M
300-02BC was used in Sample Preparation (ELISA) to demonstrate the SARS-CoV-2 icELISA test allows rapid and automated quantification of virus infection in cell culture to evaluate the efficacy of NAbs and antiviral drugs using reagents and equipment present in most routine diagnostics departments.
Mon Dec 07 00:00:00 EST 2020
EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer.
Nature cancer
Gong K,Guo G,Panchani N,Bender ME,Gerber DE,Minna JD,Fattah F,Gao B,Peyton M,Kernstine K,Mukherjee B,Burma S,Chiang CM,Zhang S,Amod Sathe A,Xing C,Dao KH,Zhao D,Akbay EA,Habib AA
300-02BC was used in Sample Preparation (WB) to investigate EGFR inhibition in non-small cell lung carcinoma.
Wed Apr 01 00:00:00 EDT 2020
Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages.
eLife
Dupont M,Souriant S,Balboa L,Vu Manh TP,Pingris K,Rousset S,Cougoule C,Rombouts Y,Poincloux R,Ben Neji M,Allers C,Kaushal D,Kuroda MJ,Benet S,Martinez-Picado J,Izquierdo-Useros N,Sasiain MDC,Maridonneau-Parini I,Neyrolles O,Vérollet C,Lugo-Villarino G
300-02BC was used in Cell Culture to uncover a deleterious role for Siglec-1 in TB-HIV-1 co-infection and open new avenues to understand TNT biology.
Mon Mar 30 00:00:00 EDT 2020
Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity.
Cell
Liu CX,Li X,Nan F,Jiang S,Gao X,Guo SK,Xue W,Cui Y,Dong K,Ding H,Qu B,Zhou Z,Shen N,Yang L,Chen LL
Thu May 02 00:00:00 EDT 2019
A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication.
Cell
Grandclaudon M,Perrot-Dockès M,Trichot C,Karpf L,Abouzid O,Chauvin C,Sirven P,Abou-Jaoudé W,Berger F,Hupé P,Thieffry D,Sansonnet L,Chiquet J,Lévy-Leduc C,Soumelis V
300-02BC was used in Sample Prep to describe an integrative approach involving protein-level measurement of multiple communication signals coupled to output responses in receiving cells and mathematical modeling to uncover input-output relationships and interactions between signals.
Thu Oct 03 00:00:00 EDT 2019
A Quantitative Multivariate Model of Human Dendritic Cell-T Helper Cell Communication.
Cell
Grandclaudon M,Perrot-Dockès M,Trichot C,Karpf L,Abouzid O,Chauvin C,Sirven P,Abou-Jaoudé W,Berger F,Hupé P,Thieffry D,Sansonnet L,Chiquet J,Lévy-Leduc C,Soumelis V
300-02BC was used in Sample Prep to describe an integrative approach involving protein-level measurement of multiple communication signals coupled to output responses in receiving cells and mathematical modeling to uncover input-output relationships and interactions between signals.
Thu Oct 03 00:00:00 EDT 2019
Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity.
Cell
Cadena C,Ahmad S,Xavier A,Willemsen J,Park S,Park JW,Oh SW,Fujita T,Hou F,Binder M,Hur S
Thu May 16 00:00:00 EDT 2019
The herpesviral antagonist m152 reveals differential activation of STING-dependent IRF and NF-κB signaling and STING's dual role during MCMV infection.
The EMBO journal
Stempel M,Chan B,Juranić Lisnić V,Krmpotić A,Hartung J,Paludan SR,Füllbrunn N,Lemmermann NA,Brinkmann MM
Fri Mar 01 00:00:00 EST 2019
Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 + subset.
Aging cell
Martini H,Iacovoni JS,Maggiorani D,Dutaur M,Marsal DJ,Roncalli J,Itier R,Dambrin C,Pizzinat N,Mialet-Perez J,Cussac D,Parini A,Lefevre L,Douin-Echinard V
Tue Oct 01 00:00:00 EDT 2019
Interferon-regulated suprabasin is essential for stress-induced stem-like cell conversion and therapy resistance of human malignancies.
Molecular oncology
Hubackova S,Pribyl M,Kyjacova L,Moudra A,Dzijak R,Salovska B,Strnad H,Tambor V,Imrichova T,Svec J,Vodicka P,Vaclavikova R,Rob L,Bartek J,Hodny Z
Mon Jul 01 00:00:00 EDT 2019
Multiple Pathways To Avoid Beta Interferon Sensitivity of HIV-1 by Mutations in Capsid.
Journal of virology
Sultana T,Mamede JI,Saito A,Ode H,Nohata K,Cohen R,Nakayama EE,Iwatani Y,Yamashita M,Hope TJ,Shioda T
300-02BC was used in In vitro experiments to investigate type I interferons in HIV-1 replication.
Sun Dec 01 00:00:00 EST 2019
The interferon stimulated gene viperin, restricts Shigella. flexneri in vitro.
Scientific reports
Helbig KJ,Teh MY,Crosse KM,Monson EA,Smith M,Tran EN,Standish AJ,Morona R,Beard MR
Wed Oct 30 00:00:00 EDT 2019
Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase.
The Journal of biological chemistry
Jobin PG,Solis N,Machado Y,Bell PA,Kwon NH,Kim S,Overall CM,Butler GS
Fri Aug 30 00:00:00 EDT 2019
IL-1β/TNF-α/IL-6 inflammatory cytokines promote STAT1-dependent induction of CH25H in Zika virus-infected human macrophages.
The Journal of biological chemistry
Magoro T,Dandekar A,Jennelle LT,Bajaj R,Lipkowitz G,Angelucci AR,Bessong PO,Hahn YS
Fri Oct 04 00:00:00 EDT 2019
IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation.
Nature communications
Kumaran Satyanarayanan S,El Kebir D,Soboh S,Butenko S,Sekheri M,Saadi J,Peled N,Assi S,Othman A,Schif-Zuck S,Feuermann Y,Barkan D,Sher N,Filep JG,Ariel A
Fri Aug 02 00:00:00 EDT 2019
IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation.
Nature communications
Kumaran Satyanarayanan S,El Kebir D,Soboh S,Butenko S,Sekheri M,Saadi J,Peled N,Assi S,Othman A,Schif-Zuck S,Feuermann Y,Barkan D,Sher N,Filep JG,Ariel A
Fri Aug 02 00:00:00 EDT 2019
IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation.
Nature communications
Kumaran Satyanarayanan S,El Kebir D,Soboh S,Butenko S,Sekheri M,Saadi J,Peled N,Assi S,Othman A,Schif-Zuck S,Feuermann Y,Barkan D,Sher N,Filep JG,Ariel A
Fri Aug 02 00:00:00 EDT 2019
iRGD synergizes with PD-1 knockout immunotherapy by enhancing lymphocyte infiltration in gastric cancer.
Nature communications
Ding N,Zou Z,Sha H,Su S,Qian H,Meng F,Chen F,Du S,Zhou S,Chen H,Zhang L,Yang J,Wei J,Liu B
Fri Mar 22 00:00:00 EDT 2019
Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure.
Cell death & disease
Bittel M,Kremer AE,Stürzl M,Wirtz S,Stolzer I,Neurath MF,Ballon G,Günther C
Thu Nov 21 00:00:00 EST 2019
Production Strategies for Pentamer-Positive Subviral Dense Bodies as a Safe Human Cytomegalovirus Vaccine.
Vaccines
Gogesch P,Penner I,Krauter S,Büscher N,Grode L,Aydin I,Plachter B
300-02BC was used in In vitro experiments to investigate development of a vaccine against human cytomegalovirus in children.
Sun Sep 01 00:00:00 EDT 2019
FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.
Nature
Meng X,Liu X,Guo X,Jiang S,Chen T,Hu Z,Liu H,Bai Y,Xue M,Hu R,Sun SC,Liu X,Zhou P,Huang X,Wei L,Yang W,Xu C
Sat Dec 01 00:00:00 EST 2018
FBXO38 mediates PD-1 ubiquitination and regulates anti-tumour immunity of T cells.
Nature
Meng X,Liu X,Guo X,Jiang S,Chen T,Hu Z,Liu H,Bai Y,Xue M,Hu R,Sun SC,Liu X,Zhou P,Huang X,Wei L,Yang W,Xu C
Sat Dec 01 00:00:00 EST 2018
Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation.
Cell
Ahmad S,Mu X,Yang F,Greenwald E,Park JW,Jacob E,Zhang CZ,Hur S
Thu Feb 08 00:00:00 EST 2018
Intrinsic Immunity Shapes Viral Resistance of Stem Cells.
Cell
Wu X,Dao Thi VL,Huang Y,Billerbeck E,Saha D,Hoffmann HH,Wang Y,Silva LAV,Sarbanes S,Sun T,Andrus L,Yu Y,Quirk C,Li M,MacDonald MR,Schneider WM,An X,Rosenberg BR,Rice CM
Thu Jan 25 00:00:00 EST 2018
Innate-like Cytotoxic Function of Bystander-Activated CD8+ T Cells Is Associated with Liver Injury in Acute Hepatitis A.
Immunity
Kim J,Chang DY,Lee HW,Lee H,Kim JH,Sung PS,Kim KH,Hong SH,Kang W,Lee J,Shin SY,Yu HT,You S,Choi YS,Oh I,Lee DH,Lee DH,Jung MK,Suh KS,Hwang S,Kim W,Park SH,Kim HJ,Shin EC
Tue Jan 16 00:00:00 EST 2018
Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection.
Cell host & microbe
Johnson JS,Lucas SY,Amon LM,Skelton S,Nazitto R,Carbonetti S,Sather DN,Littman DR,Aderem A
300-02BC was used in Cell Culture to study how dendritic cells (DCs) detect HIV-1 in distinct phases, before and after virus integration in response to reverse transcription.
Wed Mar 14 00:00:00 EDT 2018
STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells.
The Journal of clinical investigation
Liu Y,Lv J,Liu J,Liang X,Jin X,Xie J,Zhang L,Chen D,Fiskesund R,Tang K,Ma J,Zhang H,Dong W,Mo S,Zhang T,Cheng F,Zhou Y,Jia Q,Zhu B,Kong Y,Guo J,Zhang H,Hu ZW,Cao X,Qin FX,Huang B
Thu Mar 01 00:00:00 EST 2018
Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection.
Proceedings of the National Academy of Sciences of the United States of America
Zimmer B,Ewaleifoh O,Harschnitz O,Lee YS,Peneau C,McAlpine JL,Liu B,Tchieu J,Steinbeck JA,Lafaille F,Volpi S,Notarangelo LD,Casanova JL,Zhang SY,Smith GA,Studer L
Tue Sep 11 00:00:00 EDT 2018
IL-12+IL-18 Cosignaling in Human Macrophages and Lung Epithelial Cells Activates Cathelicidin and Autophagy, Inhibiting Intracellular Mycobacterial Growth.
Journal of immunology (Baltimore, Md. : 1950)
Yang R,Yang E,Shen L,Modlin RL,Shen H,Chen ZW
Sun Apr 01 00:00:00 EDT 2018
IFITM proteins inhibit HIV-1 protein synthesis.
Scientific reports
Lee WJ,Fu RM,Liang C,Sloan RD
Fri Sep 28 00:00:00 EDT 2018
TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis.
Nature communications
Zhang HX,Xu ZS,Lin H,Li M,Xia T,Cui K,Wang SY,Li Y,Shu HB,Wang YY
Fri Aug 24 00:00:00 EDT 2018
Compound heterozygous TYK2 mutations underlie primary immunodeficiency with T-cell lymphopenia.
Scientific reports
Nemoto M,Hattori H,Maeda N,Akita N,Muramatsu H,Moritani S,Kawasaki T,Maejima M,Ode H,Hachiya A,Sugiura W,Yokomaku Y,Horibe K,Iwatani Y
Thu May 03 00:00:00 EDT 2018
Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop.
Nature communications
Liu Z,Qin Q,Wu C,Li H,Shou J,Yang Y,Gu M,Ma C,Lin W,Zou Y,Zhang Y,Ma F,Sun J,Wang X
Tue Jul 17 00:00:00 EDT 2018
Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity.
Cell
Chen K,Liu J,Liu S,Xia M,Zhang X,Han D,Jiang Y,Wang C,Cao X
300-02BC was used in In vitro experiments to identify STAT1 methylation on K525 catalyzed by the methyltransferase SETD2 as an essential signaling event for IFNα-dependent antiviral immunity and indicates potential of SETD2 in controlling viral infections.
Thu Jul 27 00:00:00 EDT 2017
Detection of interferon alpha protein reveals differential levels and cellular sources in disease.
The Journal of experimental medicine
Rodero MP,Decalf J,Bondet V,Hunt D,Rice GI,Werneke S,McGlasson SL,Alyanakian MA,Bader-Meunier B,Barnerias C,Bellon N,Belot A,Bodemer C,Briggs TA,Desguerre I,Frémond ML,Hully M,van den Maagdenberg AMJM,Melki I,Meyts I,Musset L,Pelzer N,Quartier P,Terwindt GM,Wardlaw J,Wiseman S,Rieux-Laucat F,Rose Y,Neven B,Hertel C,Hayday A,Albert ML,Rozenberg F,Crow YJ,Duffy D
Mon May 01 00:00:00 EDT 2017
Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-γ.
European journal of immunology
Dixon KO,O'Flynn J,Klar-Mohamad N,Daha MR,van Kooten C
Wed Mar 01 00:00:00 EST 2017
The STAT4/MLL1 Epigenetic Axis Regulates the Antimicrobial Functions of Murine Macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Carson WF,Cavassani KA,Soares EM,Hirai S,Kittan NA,Schaller MA,Scola MM,Joshi A,Matsukawa A,Aronoff DM,Johnson CN,Dou Y,Gallagher KA,Kunkel SL
Fri Sep 01 00:00:00 EDT 2017
Type III IFNs Are Commonly Induced by Bacteria-Sensing TLRs and Reinforce Epithelial Barriers during Infection.
Journal of immunology (Baltimore, Md. : 1950)
Odendall C,Voak AA,Kagan JC
Wed Nov 01 00:00:00 EDT 2017
Type I interferons drive inflammasome-independent emergency monocytopoiesis during endotoxemia.
Scientific reports
Lasseaux C,Fourmaux MP,Chamaillard M,Poulin LF
Tue Dec 05 00:00:00 EST 2017
Innate immune recognition of double-stranded RNA triggers increased expression of NKG2D ligands after virus infection.
The Journal of biological chemistry
Esteso G,Guerra S,Valés-Gómez M,Reyburn HT
Fri Dec 15 00:00:00 EST 2017
Enterovirus 71 suppresses interferon responses by blocking Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling through inducing karyopherin-α1 degradation.
The Journal of biological chemistry
Wang C,Sun M,Yuan X,Ji L,Jin Y,Cardona CJ,Xing Z
Fri Jun 16 00:00:00 EDT 2017
Hypoxia triggers IFN-I production in muscle: Implications in dermatomyositis.
Scientific reports
De Luna N,Suárez-Calvet X,Lleixà C,Diaz-Manera J,Olivé M,Illa I,Gallardo E
Thu Aug 17 00:00:00 EDT 2017
Human rhinovirus-induced inflammatory responses are inhibited by phosphatidylserine containing liposomes.
Mucosal immunology
Stokes CA,Kaur R,Edwards MR,Mondhe M,Robinson D,Prestwich EC,Hume RD,Marshall CA,Perrie Y,O'Donnell VB,Harwood JL,Sabroe I,Parker LC
Thu Sep 01 00:00:00 EDT 2016
TRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A protein.
Scientific reports
Wang S,Chen Y,Li C,Wu Y,Guo L,Peng C,Huang Y,Cheng G,Qin FX
Wed Aug 31 00:00:00 EDT 2016
Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency.
The Journal of clinical investigation
Walter JE,Rosen LB,Csomos K,Rosenberg JM,Mathew D,Keszei M,Ujhazi B,Chen K,Lee YN,Tirosh I,Dobbs K,Al-Herz W,Cowan MJ,Puck J,Bleesing JJ,Grimley MS,Malech H,De Ravin SS,Gennery AR,Abraham RS,Joshi AY,Boyce TG,Butte MJ,Nadeau KC,Balboni I,Sullivan KE,Akhter J,Adeli M,El-Feky RA,El-Ghoneimy DH,Dbaibo G,Wakim R,Azzari C,Palma P,Cancrini C,Capuder K,Condino-Neto A,Costa-Carvalho BT,Oliveira JB,Roifman C,Buchbinder D,Kumanovics A,Franco JL,Niehues T,Schuetz C,Kuijpers T,Yee C,Chou J,Masaad MJ,Geha R,Uzel G,Gelman R,Holland SM,Recher M,Utz PJ,Browne SK,Notarangelo LD
Mon Nov 02 00:00:00 EST 2015
Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome.
The Journal of experimental medicine
Kreins AY,Ciancanelli MJ,Okada S,Kong XF,Ramírez-Alejo N,Kilic SS,El Baghdadi J,Nonoyama S,Mahdaviani SA,Ailal F,Bousfiha A,Mansouri D,Nievas E,Ma CS,Rao G,Bernasconi A,Sun Kuehn H,Niemela J,Stoddard J,Deveau P,Cobat A,El Azbaoui S,Sabri A,Lim CK,Sundin M,Avery DT,Halwani R,Grant AV,Boisson B,Bogunovic D,Itan Y,Moncada-Velez M,Martinez-Barricarte R,Migaud M,Deswarte C,Alsina L,Kotlarz D,Klein C,Muller-Fleckenstein I,Fleckenstein B,Cormier-Daire V,Rose-John S,Picard C,Hammarstrom L,Puel A,Al-Muhsen S,Abel L,Chaussabel D,Rosenzweig SD,Minegishi Y,Tangye SG,Bustamante J,Casanova JL,Boisson-Dupuis S
Mon Sep 21 00:00:00 EDT 2015
Porcine bocavirus NP1 negatively regulates interferon signaling pathway by targeting the DNA-binding domain of IRF9.
Virology
Zhang R,Fang L,Wang D,Cai K,Zhang H,Xie L,Li Y,Chen H,Xiao S
300-02BC was used in In vitro experiments to screen the structural and non-structural proteins encoded by porcine bocavirus (PBoV) to demonstrate that the non-structural protein NP1 significantly suppresses IFN-stimulated response element (ISRE) activity and subsequent IFN-stimulated gene (ISG) expression.
Sun Nov 01 00:00:00 EDT 2015
Activation of vascular endothelial growth factor receptor-3 in macrophages restrains TLR4-NF-κB signaling and protects against endotoxin shock.
Immunity
Zhang Y,Lu Y,Ma L,Cao X,Xiao J,Chen J,Jiao S,Gao Y,Liu C,Duan Z,Li D,He Y,Wei B,Wang H
Thu Apr 17 00:00:00 EDT 2014
A CD8 T cell/indoleamine 2,3-dioxygenase axis is required for mesenchymal stem cell suppression of human systemic lupus erythematosus.
Arthritis & rheumatology (Hoboken, N.J.)
Wang D,Feng X,Lu L,Konkel JE,Zhang H,Chen Z,Li X,Gao X,Lu L,Shi S,Chen W,Sun L
Fri Aug 01 00:00:00 EDT 2014
Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival.
Journal of immunology (Baltimore, Md. : 1950)
Kis-Toth K,Tsokos GC
Thu May 01 00:00:00 EDT 2014
Regulation of activation-associated microRNA accumulation rates during monocyte-to-macrophage differentiation.
The Journal of biological chemistry
Eigsti RL,Sudan B,Wilson ME,Graff JW
Fri Oct 10 00:00:00 EDT 2014
Tumor progression locus 2-dependent oxidative burst drives phosphorylation of extracellular signal-regulated kinase during TLR3 and 9 signaling.
The Journal of biological chemistry
Kuriakose T,Rada B,Watford WT
Fri Dec 26 00:00:00 EST 2014
Antiviral responses in mouse embryonic stem cells: differential development of cellular mechanisms in type I interferon production and response.
The Journal of biological chemistry
Wang R,Wang J,Acharya D,Paul AM,Bai F,Huang F,Guo YL
Fri Sep 05 00:00:00 EDT 2014
Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines.
Immunity
Obermoser G,Presnell S,Domico K,Xu H,Wang Y,Anguiano E,Thompson-Snipes L,Ranganathan R,Zeitner B,Bjork A,Anderson D,Speake C,Ruchaud E,Skinner J,Alsina L,Sharma M,Dutartre H,Cepika A,Israelsson E,Nguyen P,Nguyen QA,Harrod AC,Zurawski SM,Pascual V,Ueno H,Nepom GT,Quinn C,Blankenship D,Palucka K,Banchereau J,Chaussabel D
Thu Apr 18 00:00:00 EDT 2013
Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis.
Journal of immunology (Baltimore, Md. : 1950)
Hou L,Jie Z,Desai M,Liang Y,Soong L,Wang T,Sun J
Tue Jan 15 00:00:00 EST 2013
FoxO1 negatively regulates cellular antiviral response by promoting degradation of IRF3.
The Journal of biological chemistry
Lei CQ,Zhang Y,Xia T,Jiang LQ,Zhong B,Shu HB
Fri May 03 00:00:00 EDT 2013
Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response.
Proceedings of the National Academy of Sciences of the United States of America
Perona-Wright G,Kohlmeier JE,Bassity E,Freitas TC,Mohrs K,Cookenham T,Situ H,Pearce EJ,Woodland DL,Mohrs M
Tue Nov 06 00:00:00 EST 2012
SAM-pointed domain ETS factor mediates epithelial cell-intrinsic innate immune signaling during airway mucous metaplasia.
Proceedings of the National Academy of Sciences of the United States of America
Korfhagen TR,Kitzmiller J,Chen G,Sridharan A,Haitchi HM,Hegde RS,Divanovic S,Karp CL,Whitsett JA
Tue Oct 09 00:00:00 EDT 2012
Type I interferon induces CX3CL1 (fractalkine) and CCL5 (RANTES) production in human pulmonary vascular endothelial cells.
Clinical and experimental immunology
Nakano M,Fujii T,Hashimoto M,Yukawa N,Yoshifuji H,Ohmura K,Nakaizumi A,Mimori T
Mon Oct 01 00:00:00 EDT 2012
Involvement of heat shock protein 27 in the susceptibility of KT human breast cancer cells to UVC and interferon lethality.
Experimental and therapeutic medicine
Tong XB,Kita K,Chen SP,Jiang X,Sugaya S,Jing WL,Zhang SF,Suzuki N
Thu Nov 01 00:00:00 EDT 2012
Triggering of the dsRNA sensors TLR3, MDA5, and RIG-I induces CD55 expression in synovial fibroblasts.
PloS one
Karpus ON,Heutinck KM,Wijnker PJ,Tak PP,Hamann J
Wed Sep 19 00:00:00 EDT 2012
Covalent protein modification with ISG15 via a conserved cysteine in the hinge region.
PloS one
Bade VN,Nickels J,Keusekotten K,Praefcke GJ
Tue Oct 02 00:00:00 EDT 2012
Type I interferon inhibits interleukin-1 production and inflammasome activation.
Immunity
Guarda G,Braun M,Staehli F,Tardivel A,Mattmann C,Förster I,Farlik M,Decker T,Du Pasquier RA,Romero P,Tschopp J
Fri Feb 25 00:00:00 EST 2011
Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection.
Immunity
Mayer-Barber KD,Andrade BB,Barber DL,Hieny S,Feng CG,Caspar P,Oland S,Gordon S,Sher A
Fri Dec 23 00:00:00 EST 2011
Severe impairment of IFN-γ and IFN-α responses in cells of a patient with a novel STAT1 splicing mutation.
Blood
Vairo D,Tassone L,Tabellini G,Tamassia N,Gasperini S,Bazzoni F,Plebani A,Porta F,Notarangelo LD,Parolini S,Giliani S,Badolato R
Thu Aug 18 00:00:00 EDT 2011
Control of bone formation by the serpentine receptor Frizzled-9.
The Journal of cell biology
Albers J,Schulze J,Beil FT,Gebauer M,Baranowsky A,Keller J,Marshall RP,Wintges K,Friedrich FW,Priemel M,Schilling AF,Rueger JM,Cornils K,Fehse B,Streichert T,Sauter G,Jakob F,Insogna KL,Pober B,Knobeloch KP,Francke U,Amling M,Schinke T
Mon Mar 21 00:00:00 EDT 2011
Protection from RNA and DNA viruses by IL-32.
Journal of immunology (Baltimore, Md. : 1950)
Zepp JA,Nold-Petry CA,Dinarello CA,Nold MF
Fri Apr 01 00:00:00 EDT 2011
Impairment of plasmacytoid dendritic cells for IFN production by the ligand for immunoglobulin-like transcript 7 expressed on human cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Tsukamoto N,Okada S,Onami Y,Sasaki Y,Umezawa K,Kawakami Y
Tue Sep 15 00:00:00 EDT 2009
Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.
Journal of immunology (Baltimore, Md. : 1950)
Ablasser A,Poeck H,Anz D,Berger M,Schlee M,Kim S,Bourquin C,Goutagny N,Jiang Z,Fitzgerald KA,Rothenfusser S,Endres S,Hartmann G,Hornung V
Mon Jun 01 00:00:00 EDT 2009
Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway.
Journal of immunology (Baltimore, Md. : 1950)
Scutera S,Fraone T,Musso T,Cappello P,Rossi S,Pierobon D,Orinska Z,Paus R,Bulfone-Paus S,Giovarelli M
Tue Sep 01 00:00:00 EDT 2009
Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance.
Journal of immunology (Baltimore, Md. : 1950)
Biswas SK,Bist P,Dhillon MK,Kajiji T,Del Fresno C,Yamamoto M,Lopez-Collazo E,Akira S,Tergaonkar V
Sat Sep 15 00:00:00 EDT 2007
STAT6-dependent differentiation and production of IL-5 and IL-13 in murine NK2 cells.
Journal of immunology (Baltimore, Md. : 1950)
Katsumoto T,Kimura M,Yamashita M,Hosokawa H,Hashimoto K,Hasegawa A,Omori M,Miyamoto T,Taniguchi M,Nakayama T
Fri Oct 15 00:00:00 EDT 2004
