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Invitrogen
Human IFN-omega Recombinant Protein
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Product Details
113951
Product Specifications
Species
Human
Expression System
E. coli
Molecular weight
20 kDa
Class
Recombinant
Type
Protein
Purity
>95%
Endotoxin concentration
<1 EU/µg
Activity
EC50 ~ 1 U/mL; determined by use of the cytopathic effect inhibition assay described in [Rubinstein, S. et al. (1981). J. Virol. 37, 755-758]; [Familletti, P.C. et al. (1981). Methods in Enzymology, Vol. 78, 387-394]. The units are determined with respect to the international reference standard for human interferon alpha A (Hu-IFN-alpha-A) provided by the National Institutes of Health [see Pestka, S. (1986). Methods in Enzymology, Academic Press, New York 119, 14-23]. Unit of activity measured on bovine MDBK cells with vesicular stomatitis virus (VSV).SV).
Conjugate
Form
Liquid
Concentration
Lot-specific
Purification
purified
Storage buffer
PBS with 2% BSA
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice (domestic); Wet or Dry ice (international)
Product Specific Information
Store at -20°C or below for retention of full activity. Thaw product vial by incubation in cold tap water until just thawed. Aliquot and refreeze unused contents to minimize effects of freeze thawing. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of product should be in buffers containing protein such as 0.1% BSA or tissue culture media with serum.
Target Information
IFN-omega is a type I interferon that can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-alpha, IFN-beta, and IFN-omega, signal through the IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-omega exhibits about 75% sequence homology with IFN-alpha, and contains two conserved disulfide bonds that are necessary for full biological activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IFN o; IFN ω; IFN-omega 1, interferon omega-1; IFNo; IFNomega; IFNW; IFNω; Interferon; Interferon alpha-II-1; Interferon o; Interferon OMEGA; Interferon omega-1; Interferon ω; interferon, omega 1
Gene Aliases: IFNW1
UniProt ID: (Human) P05000
Entrez Gene ID: (Human) 3467
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