Product References
Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B.
The Journal of clinical investigation
Azad P,Zhou D,Tu HC,Villafuerte FC,Traver D,Rana TM,Haddad GG
200-11 was used in In vitro experiments to conclude that HIKER regulates erythropoiesis in Monge's disease and acts through at least one specific target, CSNK2B, a casein kinase.
Thu Jun 01 00:00:00 EDT 2023
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
Developmental cell
Ma Y,Liu S,Gao J,Chen C,Zhang X,Yuan H,Chen Z,Yin X,Sun C,Mao Y,Zhou F,Shao Y,Liu Q,Xu J,Cheng L,Yu D,Li P,Yi P,He J,Geng G,Guo Q,Si Y,Zhao H,Li H,Banes GL,Liu H,Nakamura Y,Kurita R,Huang Y,Wang X,Wang F,Fang G,Engel JD,Shi L,Zhang YE,Yu J
200-11 was used in Sample Preparation (FC/FACS) to investigate pseudogene phenotypic effects.
Mon Feb 22 00:00:00 EST 2021
Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses.
Cell reports
Yu K,Hammerschmidt SI,Permanyer M,Galla M,Rothe M,Zheng X,Werth K,Martens R,Lueder Y,Janssen A,Friedrichsen M,Bernhardt G,Förster R
Tue Jun 22 00:00:00 EDT 2021
Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production.
Developmental cell
Frame JM,Kubaczka C,Long TL,Esain V,Soto RA,Hachimi M,Jing R,Shwartz A,Goessling W,Daley GQ,North TE
200-11 was used in In vitro experiments to establish the inflammasome as a conserved metabolic sensor that expands HSPC production in vivo and in vitro.
Mon Oct 26 00:00:00 EDT 2020
Good Manufacturing Practice-Grade of Megakaryocytes Produced by a Novel Ex Vivo Culturing Platform.
Clinical and translational science
Guan X,Wang L,Wang H,Wang H,Dai W,Jiang Y
Sun Nov 01 00:00:00 EDT 2020
Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance.
Nature communications
Barbier V,Erbani J,Fiveash C,Davies JM,Tay J,Tallack MR,Lowe J,Magnani JL,Pattabiraman DR,Perkins AC,Lisle J,Rasko JEJ,Levesque JP,Winkler IG
Mon Apr 27 00:00:00 EDT 2020
Enabling Large-Scale Ex Vivo Production of Megakaryocytes from CD34+ Cells Using Gas-Permeable Surfaces.
Stem cells translational medicine
Martinez AF,Miller WM
Mon Jul 01 00:00:00 EDT 2019
Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid.
Developmental cell
Sozen B,Cox AL,De Jonghe J,Bao M,Hollfelder F,Glover DM,Zernicka-Goetz M
200-11 was used in Cell Culture to show that mouse embryonic stem cells cultured under extended pluripotent conditions (EPSCs) can be partnered with trophoblast stem cells to self-organize into blastocyst-like structures with all three embryonic and extra-embryonic lineages.
Mon Dec 16 00:00:00 EST 2019
Blastocyst-like structures generated solely from stem cells.
Nature
Rivron NC,Frias-Aldeguer J,Vrij EJ,Boisset JC,Korving J,Vivié J,Truckenmüller RK,van Oudenaarden A,van Blitterswijk CA,Geijsen N
Tue May 01 00:00:00 EDT 2018
Rhesus Macaque Myeloid-Derived Suppressor Cells Demonstrate T Cell Inhibitory Functions and Are Transiently Increased after Vaccination.
Journal of immunology (Baltimore, Md. : 1950)
Lin A,Liang F,Thompson EA,Vono M,Ols S,Lindgren G,Hassett K,Salter H,Ciaramella G,Loré K
Mon Jan 01 00:00:00 EST 2018
MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1.
Stem cell reports
Wang H,Liu C,Liu X,Wang M,Wu D,Gao J,Su P,Nakahata T,Zhou W,Xu Y,Shi L,Ma F,Zhou J
Tue Feb 13 00:00:00 EST 2018
Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In Vitro.
Stem cell reports
Garcia-Alegria E,Menegatti S,Fadlullah MZH,Menendez P,Lacaud G,Kouskoff V
Tue Nov 13 00:00:00 EST 2018
Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia.
Nature communications
Latham SL,Ehmke N,Reinke PYA,Taft MH,Eicke D,Reindl T,Stenzel W,Lyons MJ,Friez MJ,Lee JA,Hecker R,Frühwald MC,Becker K,Neuhann TM,Horn D,Schrock E,Niehaus I,Sarnow K,Grützmann K,Gawehn L,Klink B,Rump A,Chaponnier C,Figueiredo C,Knöfler R,Manstein DJ,Di Donato N
Fri Oct 12 00:00:00 EDT 2018
Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells.
Scientific reports
MacLean GA,McEldoon J,Huang J,Allred J,Canver MC,Orkin SH
Tue May 22 00:00:00 EDT 2018
Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells.
Stem cell reports
Kauts ML,De Leo B,Rodríguez-Seoane C,Ronn R,Glykofrydis F,Maglitto A,Kaimakis P,Basi M,Taylor H,Forrester L,Wilkinson AC,Göttgens B,Saunders P,Dzierzak E
Tue Oct 09 00:00:00 EDT 2018
JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.
The Journal of clinical investigation
Wang S,Liang K,Hu Q,Li P,Song J,Yang Y,Yao J,Mangala LS,Li C,Yang W,Park PK,Hawke DH,Zhou J,Zhou Y,Xia W,Hung MC,Marks JR,Gallick GE,Lopez-Berestein G,Flores ER,Sood AK,Huang S,Yu D,Yang L,Lin C
Fri Dec 01 00:00:00 EST 2017
JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.
The Journal of clinical investigation
Wang S,Liang K,Hu Q,Li P,Song J,Yang Y,Yao J,Mangala LS,Li C,Yang W,Park PK,Hawke DH,Zhou J,Zhou Y,Xia W,Hung MC,Marks JR,Gallick GE,Lopez-Berestein G,Flores ER,Sood AK,Huang S,Yu D,Yang L,Lin C
Fri Dec 01 00:00:00 EST 2017
ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans.
The Journal of experimental medicine
Lyons JJ,Liu Y,Ma CA,Yu X,O'Connell MP,Lawrence MG,Zhang Y,Karpe K,Zhao M,Siegel AM,Stone KD,Nelson C,Jones N,DiMaggio T,Darnell DN,Mendoza-Caamal E,Orozco L,Hughes JD,McElwee J,Hohman RJ,Frischmeyer-Guerrerio PA,Rothenberg ME,Freeman AF,Holland SM,Milner JD
Mon Mar 06 00:00:00 EST 2017
Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling.
Oncogene
Junk DJ,Bryson BL,Smigiel JM,Parameswaran N,Bartel CA,Jackson MW
200-11 was used in In vitro experiments to study the specific tumor microenvironment (TME) which most actively control cancer cell plasticity for metastasis.
Thu Jul 13 00:00:00 EDT 2017
Lin- CD34hi CD117int/hi FcεRI+ cells in human blood constitute a rare population of mast cell progenitors.
Blood
Dahlin JS,Malinovschi A,Öhrvik H,Sandelin M,Janson C,Alving K,Hallgren J
Thu Jan 28 00:00:00 EST 2016
Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.
Stem cells translational medicine
Jackson M,Ma R,Taylor AH,Axton RA,Easterbrook J,Kydonaki M,Olivier E,Marenah L,Stanley EG,Elefanty AG,Mountford JC,Forrester LM
200-11 was used in Cell Culture to investigate whether activation of exogenous HOXB4 promotes the production of more mature, definitive red blood cells.
Mon Aug 01 00:00:00 EDT 2016
Thrombopoietin/TGF-β1 Loop Regulates Megakaryocyte Extracellular Matrix Component Synthesis.
Stem cells (Dayton, Ohio)
Abbonante V,Di Buduo CA,Gruppi C,Malara A,Gianelli U,Celesti G,Anselmo A,Laghi L,Vercellino M,Visai L,Iurlo A,Moratti R,Barosi G,Rosti V,Balduini A
Fri Apr 01 00:00:00 EDT 2016
GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells.
Stem cell reports
D'Souza SS,Maufort J,Kumar A,Zhang J,Smuga-Otto K,Thomson JA,Slukvin II
Tue Feb 09 00:00:00 EST 2016
Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.
Nature communications
Grover A,Sanjuan-Pla A,Thongjuea S,Carrelha J,Giustacchini A,Gambardella A,Macaulay I,Mancini E,Luis TC,Mead A,Jacobsen SE,Nerlov C
Thu Mar 24 00:00:00 EDT 2016
Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor.
The Journal of biological chemistry
An B,Abbonante V,Xu H,Gavriilidou D,Yoshizumi A,Bihan D,Farndale RW,Kaplan DL,Balduini A,Leitinger B,Brodsky B
Fri Feb 26 00:00:00 EST 2016
Contrasting roles for C/EBPα and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects.
Stem cells (Dayton, Ohio)
Fleenor CJ,Rozhok AI,Zaberezhnyy V,Mathew D,Kim J,Tan AC,Bernstein ID,DeGregori J
Wed Apr 01 00:00:00 EDT 2015
Generation of a lentiviral vector producer cell clone for human Wiskott-Aldrich syndrome gene therapy.
Molecular therapy. Methods & clinical development
Wielgosz MM,Kim YS,Carney GG,Zhan J,Reddivari M,Coop T,Heath RJ,Brown SA,Nienhuis AW
200-11 was used in In vitro experiments to show that the producer cell line and the specific monoclonal antibody will facilitate the development of a clinical protocol for gene transfer into WAS protein deficient stem cells.
Mon Jun 08 00:00:00 EDT 2015
Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation.
The Journal of clinical investigation
Bluteau D,Balduini A,Balayn N,Currao M,Nurden P,Deswarte C,Leverger G,Noris P,Perrotta S,Solary E,Vainchenker W,Debili N,Favier R,Raslova H
Sat Feb 01 00:00:00 EST 2014
BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.
The Journal of experimental medicine
Berres ML,Lim KP,Peters T,Price J,Takizawa H,Salmon H,Idoyaga J,Ruzo A,Lupo PJ,Hicks MJ,Shih A,Simko SJ,Abhyankar H,Chakraborty R,Leboeuf M,Beltrão M,Lira SA,Heym KM,Bigley V,Collin M,Manz MG,McClain K,Merad M,Allen CE
Mon Apr 07 00:00:00 EDT 2014
Definition of the native and denatured type II collagen binding site for fibronectin using a recombinant collagen system.
The Journal of biological chemistry
An B,Abbonante V,Yigit S,Balduini A,Kaplan DL,Brodsky B
Fri Feb 21 00:00:00 EST 2014
The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model.
Blood
Sportoletti P,Varasano E,Rossi R,Bereshchenko O,Cecchini D,Gionfriddo I,Bolli N,Tiacci E,Intermesoli T,Zanghì P,Masciulli A,Martelli MP,Falzetti F,Martelli MF,Falini B
Thu Apr 25 00:00:00 EDT 2013
Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression.
Blood
Laperrousaz B,Jeanpierre S,Sagorny K,Voeltzel T,Ramas S,Kaniewski B,Ffrench M,Salesse S,Nicolini FE,Maguer-Satta V
Thu Nov 28 00:00:00 EST 2013
Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model.
Blood
Kubovcakova L,Lundberg P,Grisouard J,Hao-Shen H,Romanet V,Andraos R,Murakami M,Dirnhofer S,Wagner KU,Radimerski T,Skoda RC
Thu Feb 14 00:00:00 EST 2013
Bovine lactoferricin-induced anti-inflammation is, in part, via up-regulation of interleukin-11 by secondary activation of STAT3 in human articular cartilage.
The Journal of biological chemistry
Yan D,Kc R,Chen D,Xiao G,Im HJ
Fri Nov 01 00:00:00 EDT 2013
Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models.
The Journal of experimental medicine
Thiollier C,Lopez CK,Gerby B,Ignacimouttou C,Poglio S,Duffourd Y,Guégan J,Rivera-Munoz P,Bluteau O,Mabialah V,Diop M,Wen Q,Petit A,Bauchet AL,Reinhardt D,Bornhauser B,Gautheret D,Lecluse Y,Landman-Parker J,Radford I,Vainchenker W,Dastugue N,de Botton S,Dessen P,Bourquin JP,Crispino JD,Ballerini P,Bernard OA,Pflumio F,Mercher T
Mon Oct 22 00:00:00 EDT 2012
Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21.
Proceedings of the National Academy of Sciences of the United States of America
Roy A,Cowan G,Mead AJ,Filippi S,Bohn G,Chaidos A,Tunstall O,Chan JK,Choolani M,Bennett P,Kumar S,Atkinson D,Wyatt-Ashmead J,Hu M,Stumpf MP,Goudevenou K,O'Connor D,Chou ST,Weiss MJ,Karadimitris A,Jacobsen SE,Vyas P,Roberts I
Tue Oct 23 00:00:00 EDT 2012
Induced transgene expression for the treatment of solid tumors by hematopoietic stem cell-based gene therapy.
Cancer gene therapy
Noyan F,Díez IA,Hapke M,Klein C,Dewey RA
Tue May 01 00:00:00 EDT 2012
AP-1 transcription factors, mucin-type molecules and MMPs regulate the IL-11 mediated invasiveness of JEG-3 and HTR-8/SVneo trophoblastic cells.
PloS one
Suman P,Godbole G,Thakur R,Morales-Prieto DM,Modi DN,Markert UR,Gupta SK
Mon May 14 00:00:00 EDT 2012
A microRNA encoded by Kaposi sarcoma-associated herpesvirus promotes B-cell expansion in vivo.
PloS one
Dahlke C,Maul K,Christalla T,Walz N,Schult P,Stocking C,Grundhoff A
Wed May 22 00:00:00 EDT 2013
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Cell
Bock C,Kiskinis E,Verstappen G,Gu H,Boulting G,Smith ZD,Ziller M,Croft GF,Amoroso MW,Oakley DH,Gnirke A,Eggan K,Meissner A
Fri Feb 04 00:00:00 EST 2011
Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice.
Cell research
Lu SJ,Li F,Yin H,Feng Q,Kimbrel EA,Hahm E,Thon JN,Wang W,Italiano JE,Cho J,Lanza R
Tue Mar 01 00:00:00 EST 2011
Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells.
Blood
Maetzig T,Brugman MH,Bartels S,Heinz N,Kustikova OS,Modlich U,Li Z,Galla M,Schiedlmeier B,Schambach A,Baum C
Thu Mar 17 00:00:00 EDT 2011
Specificity for the tumor-associated self-antigen WT1 drives the development of fully functional memory T cells in the absence of vaccination.
Blood
Pospori C,Xue SA,Holler A,Voisine C,Perro M,King J,Fallah-Arani F,Flutter B,Chakraverty R,Stauss HJ,Morris EC
Thu Jun 23 00:00:00 EDT 2011
STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus-encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma.
Blood
Kis LL,Gerasimcik N,Salamon D,Persson EK,Nagy N,Klein G,Severinson E,Klein E
Thu Jan 06 00:00:00 EST 2011
In vitro megakaryocyte differentiation and proplatelet formation in Ph-negative classical myeloproliferative neoplasms: distinct patterns in the different clinical phenotypes.
PloS one
Balduini A,Badalucco S,Pugliano MT,Baev D,De Silvestri A,Cattaneo M,Rosti V,Barosi G
Mon Nov 07 00:00:00 EST 2011
Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors.
Blood
Wölfler A,Danen-van Oorschot AA,Haanstra JR,Valkhof M,Bodner C,Vroegindeweij E,van Strien P,Novak A,Cupedo T,Touw IP
Thu Nov 18 00:00:00 EST 2010
Inducible Fli-1 gene deletion in adult mice modifies several myeloid lineage commitment decisions and accelerates proliferation arrest and terminal erythrocytic differentiation.
Blood
Starck J,Weiss-Gayet M,Gonnet C,Guyot B,Vicat JM,Morlé F
Thu Dec 02 00:00:00 EST 2010
Retinoic acid enhances the generation of hematopoietic progenitors from human embryonic stem cell-derived hemato-vascular precursors.
Blood
Yu C,Liu Y,Miao Z,Yin M,Lu W,Lv Y,Ding M,Deng H
Thu Dec 02 00:00:00 EST 2010
Serum response factor is an essential transcription factor in megakaryocytic maturation.
Blood
Halene S,Gao Y,Hahn K,Massaro S,Italiano JE,Schulz V,Lin S,Kupfer GM,Krause DS
Thu Sep 16 00:00:00 EDT 2010
Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential.
Blood
Grassinger J,Haylock DN,Williams B,Olsen GH,Nilsson SK
Thu Oct 28 00:00:00 EDT 2010
Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera.
Blood
Perna F,Gurvich N,Hoya-Arias R,Abdel-Wahab O,Levine RL,Asai T,Voza F,Menendez S,Wang L,Liu F,Zhao X,Nimer SD
Thu Oct 14 00:00:00 EDT 2010
SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis.
The Journal of experimental medicine
Yu L,Ji W,Zhang H,Renda MJ,He Y,Lin S,Cheng EC,Chen H,Krause DS,Min W
Mon Jun 07 00:00:00 EDT 2010
Role for MKL1 in megakaryocytic maturation.
Blood
Cheng EC,Luo Q,Bruscia EM,Renda MJ,Troy JA,Massaro SA,Tuck D,Schulz V,Mane SM,Berliner N,Sun Y,Morris SW,Qiu C,Krause DS
Thu Mar 19 00:00:00 EDT 2009
Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy
Modlich U,Navarro S,Zychlinski D,Maetzig T,Knoess S,Brugman MH,Schambach A,Charrier S,Galy A,Thrasher AJ,Bueren J,Baum C
Sun Nov 01 00:00:00 EDT 2009
Cell-intrinsic and vector-related properties cooperate to determine the incidence and consequences of insertional mutagenesis.
Molecular therapy : the journal of the American Society of Gene Therapy
Kustikova OS,Schiedlmeier B,Brugman MH,Stahlhut M,Bartels S,Li Z,Baum C
Tue Sep 01 00:00:00 EDT 2009
Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21.
Journal of immunology (Baltimore, Md. : 1950)
Hagn M,Schwesinger E,Ebel V,Sontheimer K,Maier J,Beyer T,Syrovets T,Laumonnier Y,Fabricius D,Simmet T,Jahrsdörfer B
Sat Aug 01 00:00:00 EDT 2009
IL-11 regulates autoimmune demyelination.
Journal of immunology (Baltimore, Md. : 1950)
Gurfein BT,Zhang Y,López CB,Argaw AT,Zameer A,Moran TM,John GR
Thu Oct 01 00:00:00 EDT 2009
Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors.
Blood
Takayama N,Nishikii H,Usui J,Tsukui H,Sawaguchi A,Hiroyama T,Eto K,Nakauchi H
Sun Jun 01 00:00:00 EDT 2008
Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation.
Journal of immunology (Baltimore, Md. : 1950)
van Beek J,van Meurs M,'t Hart BA,Brok HP,Neal JW,Chatagner A,Harris CL,Omidvar N,Morgan BP,Laman JD,Gasque P
Tue Feb 15 00:00:00 EST 2005
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research
Hemminki A,Kanerva A,Liu B,Wang M,Alvarez RD,Siegal GP,Curiel DT
Sat Feb 15 00:00:00 EST 2003
Stem cell factor can stimulate the formation of eosinophils by two types of murine eosinophil progenitor cells.
Stem cells (Dayton, Ohio)
Metcalf D,Mifsud S,Di Rago L
Wed Mar 12 00:00:00 EST 2003
